2,7,8-三甲基-4-喹啉胺 | 147147-70-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 2,7,8-三甲基-4-喹啉胺
• 英文名称: 2,7,8-Trimethylquinolin-4-amine
• CAS: 147147-70-4
• 化学式: C₁₂H₁₄N₂
• 分子量: 186.25
• InChiKey: STEFEHAUBRHNNM-UHFFFAOYSA-N

物化性质

• 沸点：
  360.5±37.0 °C(Predicted)
• 密度：
  1.109±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  38.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Bone Modulators And Methods Therewith
  申请人：Espina Virginia

  公开号：US20120065166A1

  公开（公告）日：2012-03-15

  THE INVENTION RELATES TO compositions, compounds, proteins and methods of treatment therewith. Aspects of embodiments also relate to a method of treating a patient by delivering to the tissues of said patient or administering to said patient a therapeutically effective amount of one or more compounds. Aspects of embodiments also relate to a method of detecting the presence of bone disease by machine-assaying detectable serotonin. Aspects of embodiments also relate to methods of treating disease in subjects.
• [EN] 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF
  申请人：THE UPJOHN COMPANY

  公开号：WO1992022533A1

  公开（公告）日：1992-12-23

  (EN) The present invention provides a compound represented by general formula (1), or a pharmacologically acceptable ester or salt thereof, as well as a composition for preventing or treating hypertension or congestive heart failure which comprises the compound as an active ingredient. These compounds are well absorbed and have long-lasting action.(FR) L'invention concerne un composé de formule générale (1) ou un ester ou un sel pharmacologiquement acceptable, ainsi qu'une composition permettant de prévenir ou de traiter l'hypertension ou l'insuffisance cardiaque et comprenant le composé comme ingrédient actif. Ces composés sont bien absorbés et ont une action durable.