N-(4-methyl-1-nitroacridin-9-yl)-N-propylhydroxylamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(4-methyl-1-nitroacridin-9-yl)-N-propylhydroxylamine
• 化学式: C17H17N3O3
• 分子量: 311.33
• InChiKey: LCWRPFRCWNBHRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  82.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• NITROACRIDINE/TUMOR INHIBITOR COMPOSITIONS
  申请人：NEW YORK MEDICAL COLLEGE

  公开号：EP1261325A2

  公开（公告）日：2002-12-04
• 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES
  申请人：NEW YORK MEDICAL COLLEGE

  公开号：EP1257538A2

  公开（公告）日：2002-11-20
• [EN] NITROACRIDINE/TUMOR INHIBITOR COMPOSITIONS<br/>[FR] COMPOSITIONS INHIBITRICES DE TUMEURS A BASE DE 1-NITROACRIDINE
  申请人：NEW YORK MEDICAL COLLEGE

  公开号：WO2001060351A2

  公开（公告）日：2001-08-23

  The invention is directed to 1-nitroacridine derivative(s)/tumor inhibitor(s) compositions as well as methods for using said compositions for inhibiting or preventing tumor growth, particularly, prostate cancer cells growth and metastases.
• [EN] 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES<br/>[FR] DERIVES DE 9-ALKYLAMINO-1-NITROACRIDINE
  申请人：NEW YORK MEDICAL COLLEGE

  公开号：WO2001060801A2

  公开（公告）日：2001-08-23

  The invention is directed to novel 9-hydroxyalkylamino-, 9-alkoxyalkylamino-1-nitroacridine derivatives. Methods of preparation, pharmaceutical compositions comprising said derivatives and their medical use are also encompassed by this invention.