7-Azido-6-(2-methylaziridin-1-yl)quinoline-5,8-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-Azido-6-(2-methylaziridin-1-yl)quinoline-5,8-dione
• 化学式: C12H9N5O2
• 分子量: 255.23
• InChiKey: GJIZRICTSPFJCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  64.4
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• [EN] AZIRIDINYLQUINOLINEDIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION<br/>[FR] DERIVES D'AZIRIDINYLQUINOLINEDIONE ET LEUR PROCEDE DE PREPARATION
  申请人：KOREA INST SCI & TECH

  公开号：WO2002034742A1

  公开（公告）日：2002-05-02

  The present invention relates to aziridinylquinolinedione derivatives having an anti-tumor effect of formula (1), a process for their preparation and their use as an anti-cancer agent, wherein R1 is a hydrogen atom or C¿1?-C4 alkyl; one of R?2 and R3¿ is an aziridinyl or 2-methylaziridinyl and the other one is a halogen atom, C¿1?-C4 alkoxy, azido, or amino.