1-Methyl-1-(1-methylethenyl)cyclohexane | 16580-19-1

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 1-Methyl-1-(1-methylethenyl)cyclohexane
• 英文别名: 1-methyl-1-prop-1-en-2-ylcyclohexane
• CAS: 16580-19-1
• 化学式: C₁₀H₁₈
• 分子量: 138.253
• InChiKey: GRWRWBPVDAEEOO-UHFFFAOYSA-N

物化性质

• 沸点：
  172.3 °C
• 密度：
  0.84475 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-Methyl-1-(1-methylethenyl)cyclohexane 在 kieselguhr 、 镍 作用下， 生成 1-异丙基-1-甲基环己烷
  参考文献：
  名称：

  Study in the Terpene Series. XXII.^1a Synthesis, Physical Constants and Catalytic Dehydrogenation of 1-Methyl-1-ethyl-, 1-Methyl-1-n-propyl- and 1-Methyl-1-isopropylcyclohexane^1b

  摘要：

  DOI：

  10.1021/ja01615a044
• 作为产物：
  描述：

  1-(1-甲基环己基)乙酮 在 乙醚 作用下， 生成 1-Methyl-1-(1-methylethenyl)cyclohexane
  参考文献：
  名称：

  Study in the Terpene Series. XXII.^1a Synthesis, Physical Constants and Catalytic Dehydrogenation of 1-Methyl-1-ethyl-, 1-Methyl-1-n-propyl- and 1-Methyl-1-isopropylcyclohexane^1b

  摘要：

  DOI：

  10.1021/ja01615a044

文献信息

• Organocalcium chemistry: preparation and reactions of highly reactive calcium
  作者：Tse Chong Wu、Heping Xiong、Reuben D. Rieke

  DOI：10.1021/jo00304a016

  日期：1990.8
• Chemistry of substituted (2-butene-1,4-diyl)magnesium: a facile approach to complex carbocycles, functionalized ketones and alcohols, and silicon-containing heterocycles
  作者：Reuben D. Rieke、Heping Xiong

  DOI：10.1021/jo00009a034

  日期：1991.4

  Highly reactive magnesium reacts with a wide variety of substituted 1,3-dienes to give the corresponding substituted (2-butene-1,4-diyl)magnesium complexes. Reactions of symmetrical (2-butene-1,4-diyl)magnesium with alpha,omega-alkylene dihalides form three-, four-, five-, and six-membered carbocycles. Significantly, the cyclizations are always stereospecific and completely regioselective. Depending on the initial 1,3-diene and specific electrophiles, uncyclized products can be obtained. Stepwise reactions of (2,3-dimethyl-2-butene-1,4-diyl)magnesium with two different electrophiles afford polyfunctionalized ketones with the generation of a quaternary center. Formal 1,2-additions can be effected in this manner. Substituted five- and six-membered cyclic ketones can also be synthesized in one step by this approach. Treatment of unsymmetrical (2-butene-1,4-diyl)magnesium complexes with triorganosilyl chlorides followed by cyclohexanone results in additions across a terminal double bond with high regioselectivity. Silicon-containing heterocycles or spiro compounds can be readily synthesized by using the bis-Grignard reagents.
• Facile formation of substituted 2-butene-1,4-diylmagnesium using highly reactive magnesium. A simple approach to complex carbocycles and functionalized ketones
  作者：Heping Xiong、Reuben D. Rieke

  DOI：10.1021/jo00275a001

  日期：1989.7
• Skelatal rearrangements in the reaction of trichlorosilane with t-butylcyclohexenes
  作者：Robert A. Benkeser、Robert F. Cunico

  DOI：10.1016/s0022-328x(00)81532-6

  日期：1966.10
• Study in the Terpene Series. XXII.^1a Synthesis, Physical Constants and Catalytic Dehydrogenation of 1-Methyl-1-ethyl-, 1-Methyl-1-n-propyl- and 1-Methyl-1-isopropylcyclohexane^1b
  作者：Herman Pines、Joseph Maréchal

  DOI：10.1021/ja01615a044

  日期：1955.5