Tert-butyl 2-[3-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxy-2,2-bis[[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxymethyl]propoxy]acetate | 951260-39-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Tert-butyl 2-[3-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxy-2,2-bis[[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxymethyl]propoxy]acetate
• CAS: 951260-39-2
• 化学式: C₂₃H₁₉F₂₇O₆
• 分子量: 904.357
• InChiKey: SKCMGPIPNKLAEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.3
• 重原子数：
  56
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  33

反应信息

• 作为反应物：
  描述：

  Tert-butyl 2-[3-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxy-2,2-bis[[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxymethyl]propoxy]acetate 在 苯甲醚 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 2-[3-[1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propan-2-yl]oxy-2,2-bis[[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxymethyl]propoxy]acetic acid
  参考文献：
  名称：

  Jiang, Zhong-Xing; Liu, Xin; Jeong, Eun-Kee, Angewandte Chemie, International Edition, 2009, vol. 48, p. 4755 - 4758

  摘要：

  DOI：
• 作为产物：
  描述：

  溴乙酸叔丁酯 在 potassium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 0.17h， 以78%的产率得到Tert-butyl 2-[3-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxy-2,2-bis[[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]oxymethyl]propoxy]acetate
  参考文献：
  名称：

  WO2007/112100

  摘要：

  公开号：

文献信息

• HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME
  申请人：Yu Yihua

  公开号：US20090264397A1

  公开（公告）日：2009-10-22

  Disclosed are compounds comprising the structure: In one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US8252778B2
  申请人：——

  公开号：US8252778B2

  公开（公告）日：2012-08-28
• Jiang, Zhong-Xing; Liu, Xin; Jeong, Eun-Kee, Angewandte Chemie, International Edition, 2009, vol. 48, p. 4755 - 4758
  作者：Jiang, Zhong-Xing、Liu, Xin、Jeong, Eun-Kee、Yu, Yihua Bruce

  DOI：——

  日期：——
• WO2007/112100
  申请人：——

  公开号：——

  公开（公告）日：——
• Fluorous Mixture Synthesis of Asymmetric Dendrimers
  作者：Zhong-Xing Jiang、Yihua Bruce Yu

  DOI：10.1021/jo100102a

  日期：2010.3.19

  A divergent fluorous mixture synthesis (FMS) of asymmetric fluorinated dendrimers has been developed. Four generations of fluorinated dendrimers with the same fluorinated moiety were prepared with high efficiency, yield, and purity. Comparison of the physicochemical properties of these dendrimers provided Valuable information for their application and future optimization. This strategy has not only provided a practical method for the synthesis and purification of dendrimers, but also established the possibility of utilizing the same fluorinated moiety for FMS.