cis/trans-3-Methyl-1-cyclohexancarbaldehyd | 13076-16-9

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧化物
• 英文名称: cis/trans-3-Methyl-1-cyclohexancarbaldehyd
• 英文别名: 3-methyl-cyclohexanecarbaldehyde；3-Methyl-cyclohexancarbaldehyd；3-Methyl-1-formyl-cyclohexan；3-Methyl-1-methylal-cyclohexan；3-Methyl-hexahydrobenzaldehyd；Hexahydro-m-toluylaldehyd；3-Methylcyclohexane-1-carbaldehyde
• CAS: 13076-16-9
• 化学式: C₈H₁₄O
• mdl: MFCD20281401
• 分子量: 126.199
• InChiKey: VKKKNBBQMSBFCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.875
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  cis/trans-3-Methyl-1-cyclohexancarbaldehyd 、 三苯基丙基溴化 在 正丁基锂 作用下， 生成 1-甲基-3-(2-甲基-丙烯基)-环己烷 、 1-甲基-3-(2-甲基-丙烯基)-环己烷
  参考文献：
  名称：

  Hoepfner, Wolfgang; Weyerstahl, Peter, Liebigs Annalen der Chemie, 1986, # 1, p. 99 - 113

  摘要：

  DOI：
• 作为产物：
  描述：

  3-甲基环己酮 在 sodium ethanolate 作用下， 生成 cis/trans-3-Methyl-1-cyclohexancarbaldehyd
  参考文献：
  名称：

  Darzens; Lefebure, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1906, vol. 142, p. 715

  摘要：

  DOI：

文献信息

• ATPENINS
  申请人：ADELT Isabelle

  公开号：US20100168175A1

  公开（公告）日：2010-07-01

  The present invention relates to processes for preparing certain 2-pyridones and 2-pyridinols, to novel compounds of these two types and to their use as biologically active compounds, in particular for controlling harmful microorganisms in crop protection, in the medicinal field and in the protection of materials.

  本发明涉及制备特定2-吡啶酮和2-吡啶醇的过程，涉及这两种类型的新化合物以及它们作为生物活性化合物的用途，特别是用于控制农作物保护中的有害微生物，在医药领域和材料保护中。
• Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
  申请人：Peters Stefan

  公开号：US20110269791A1

  公开（公告）日：2011-11-03

  The present invention relates to compounds defined by Formula (I), wherein the groups A, B, X, m, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.

  本发明涉及由式（I）定义的化合物，其中A、B、X、m、n和o基团的定义如权利要求1中所述，具有有价值的药理活性。特别是这些化合物是11β-羟基类固醇脱氢酶（HSD）1的抑制剂，因此适用于治疗和预防可以受到该酶抑制影响的疾病，如代谢性疾病，特别是2型糖尿病、肥胖症和血脂异常。
• Antiallergy and antiinflammatory benzoxazolinones
  申请人：Pfizer Inc.

  公开号：US05086062A1

  公开（公告）日：1992-02-04

  This invention relates to certain benzoxazolinones which inhibit lipoxygenase and/or cyclooxygenase enzymes. Such compounds are useful in inhibiting such enzymes, per se, and are useful in treating allergic and inflammatory conditions in a mammal. This invention also relates to methods of inhibiting lipoxygenase and/or cyclooxygenase in a mammal with such benzoxazolinones; methods of treating an allergic condition in a mammal with such compounds; methods of treating an inflammatory condition in a mammal with such compounds; and pharmaceutical compositions comprising the benzoxazolinones hereof.

  该发明涉及一些抑制脂氧合酶和/或环氧合酶酶的苯并噁唑酮类化合物。这些化合物在抑制这些酶本身方面是有用的，并且在治疗哺乳动物的过敏和炎症症状方面也是有用的。该发明还涉及使用这种苯并噁唑酮类化合物来抑制哺乳动物中的脂氧合酶和/或环氧合酶的方法；使用这种化合物来治疗哺乳动物的过敏症状的方法；使用这种化合物来治疗哺乳动物的炎症症状的方法；以及包含这些苯并噁唑酮类化合物的药物组合物。
• [EN] 2-(N-SUBSTITUTED PIPERAZINYL) STEROID DERIVATIVES<br/>[FR] DÉRIVÉS DE STÉROÏDES DE TYPE 2-(PIPÉRAZINYLE N-SUBSTITUÉ)
  申请人：UNIV LAVAL

  公开号：WO2010060215A1

  公开（公告）日：2010-06-03

  Novel chemical agents of Formula I are described herein. More specifically, 2-(N-substituted piperazinyl) pregnane and 2-(N-substituted piperazinyl) androstane derivatives exhibiting cytotoxicity on a variety of cancer cell lines are disclosed herein. (I)

  本文描述了化学式I的新型化学试剂。更具体地，本文披露了对多种癌细胞系表现出细胞毒性的2-(N-取代哌嗪基)孕酮和2-(N-取代哌嗪基)雄烷衍生物。 (I)
• PROCESSES FOR PREPARING VINYLIDENE DIMER DERIVATIVES
  申请人：ExxonMobil Research and Engineering Company

  公开号：US20180086682A1

  公开（公告）日：2018-03-29

  This disclosure provides a process for producing vinylidene dimer derivatives by subjecting one or more vinylidene dimers and one or more carbonyl-containing compounds to a carbonyl-ene reaction, optionally in the presence of a catalyst, to produce one or more vinylidene dimer derived alcohols. This disclosure also provides a process for producing vinylidene dimer derivatives by reacting one or more vinylidene dimers with one or more carbonyl-containing compounds, optionally in the presence of a catalyst, to produce one or more vinylidene dimer derived alcohols. This disclosure further provides vinylidene dimer derivatives (e.g., vinylidene dimer derived alcohols and esters) produced by these processes. This disclosure still further provides for hydrogenating/reacting the vinylidene dimer derived alcohols with acids or anhydrides to produce vinylidene dimer derived esters. This disclosure yet further relates to lubricating ester oil base stocks, and lubricating oils containing the lubricating ester oil base stocks.

  本公开提供了一种通过将一个或多个乙烯二聚体和一个或多个含羰基化合物置于羰基-烯反应中，可选地在催化剂的存在下，生产一个或多个乙烯二聚体衍生醇的过程。本公开还提供了一种通过将一个或多个乙烯二聚体与一个或多个含羰基化合物反应，可选地在催化剂的存在下，生产一个或多个乙烯二聚体衍生醇的过程。本公开进一步提供了通过这些过程生产的乙烯二聚体衍生物（例如，乙烯二聚体衍生醇和酯）。本公开还提供了将乙烯二聚体衍生醇与酸或酐氧化/反应以生产乙烯二聚体衍生酯的方法。本公开还涉及润滑酯油基础油和含有润滑酯油基础油的润滑油。