1,5-bis-(2,4,6-trihydroxy-phenyl)-pentane-1,5-dione | 16093-48-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,5-bis-(2,4,6-trihydroxy-phenyl)-pentane-1,5-dione
• 英文别名: 1,5-Bis-(2,4,6-trihydroxy-phenyl)-pentan-1,5-dion；1,5-Bis-<2,4,6-trihydroxy-phenyl>-pentan-1,5-dion；1,5-Bis(2,4,6-trihydroxyphenyl)-1,5-pentanedione；1,5-bis(2,4,6-trihydroxyphenyl)pentane-1,5-dione
• CAS: 16093-48-4
• 化学式: C₁₇H₁₆O₈
• 分子量: 348.309
• InChiKey: CCRFYPWXKWHTRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  156
• 氢给体数：
  6
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  间苯三酚 、 戊二腈 在 盐酸 、 乙醚 、 zinc(II) chloride 作用下， 生成 1,5-bis-(2,4,6-trihydroxy-phenyl)-pentane-1,5-dione 、 5-oxo-5-(2,4,6-trihydroxy-phenyl)-valeric acid
  参考文献：
  名称：

  An exception to the rule: Ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst

  摘要：

  Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the problem behaved more like pituitary-dependent Cushing's disease and this is discussed. Furthermore, this case is one of familial dermoid cysts, another unusual phenomenon. (C) 2001, Editrice Kurtis.

  DOI：

  10.1007/bf03343930

文献信息

• An exception to the rule: Ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst
  作者：J. Watson、M. Taylor、J. Pampiglione、S. Rasbridge、Mary Armitage

  DOI：10.1007/bf03343930

  日期：2001.11

  Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the problem behaved more like pituitary-dependent Cushing's disease and this is discussed. Furthermore, this case is one of familial dermoid cysts, another unusual phenomenon. (C) 2001, Editrice Kurtis.