2,6-diphenyl-4-(1H-imidazol-1-yl)aniline | 647835-37-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-diphenyl-4-(1H-imidazol-1-yl)aniline
• 英文别名: [1,1':3',1''-Terphenyl]-2'-amine, 5'-(1H-imidazol-1-yl)-；4-imidazol-1-yl-2,6-diphenylaniline
• CAS: 647835-37-8
• 化学式: C₂₁H₁₇N₃
• 分子量: 311.386
• InChiKey: MGSKMMKGAMTOCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  过氧化苯甲酸叔丁酯 、 2,6-diphenyl-4-(1H-imidazol-1-yl)aniline 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以14%的产率得到N-tert-butoxy-4-(1H-imidazol-1-yl)-2,6-diphenylphenylaminyl
  参考文献：
  名称：

  Isolation and Magnetic Properties of Heterocycle-Carrying N-Alkoxyarylaminyl Radicals¹

  摘要：

  Two N-tert-butoxy-2,6-diaryl-4-(4-pyridyl)phenylaminyls (1) and three N-tert-butoxy-2,6-diaryl-4-(1H-imidazol-1-yl)phenylaminyls (2) were prepared by the reaction of the lithium salts of the corresponding anilines with tertbutyl peroxybenzoate. Although 1 could not be isolated as radical crystals, 2 was successfully obtained as red crystals. The X-ray crystallographic analysis and magnetic susceptibility measurements were performed for one isolated radical.

  DOI：

  10.1021/jo0302105
• 作为产物：
  描述：

  4-(1H-咪唑-1-基)苯胺 在 四(三苯基膦)钯 benzyltrimethylammonium tribromide 、 potassium carbonate 、 calcium carbonate 作用下， 以 甲醇 、 乙醇 、 二氯甲烷 、 水 、 苯 为溶剂， 反应 26.0h， 生成 2,6-diphenyl-4-(1H-imidazol-1-yl)aniline
  参考文献：
  名称：

  Isolation and Magnetic Properties of Heterocycle-Carrying N-Alkoxyarylaminyl Radicals¹

  摘要：

  Two N-tert-butoxy-2,6-diaryl-4-(4-pyridyl)phenylaminyls (1) and three N-tert-butoxy-2,6-diaryl-4-(1H-imidazol-1-yl)phenylaminyls (2) were prepared by the reaction of the lithium salts of the corresponding anilines with tertbutyl peroxybenzoate. Although 1 could not be isolated as radical crystals, 2 was successfully obtained as red crystals. The X-ray crystallographic analysis and magnetic susceptibility measurements were performed for one isolated radical.

  DOI：

  10.1021/jo0302105

文献信息

• Isolation and Magnetic Properties of Heterocycle-Carrying <i>N</i>-Alkoxyarylaminyl Radicals¹
  作者：Yozo Miura、Toshiyuki Nishi、Yoshio Teki

  DOI：10.1021/jo0302105

  日期：2003.12.1

  Two N-tert-butoxy-2,6-diaryl-4-(4-pyridyl)phenylaminyls (1) and three N-tert-butoxy-2,6-diaryl-4-(1H-imidazol-1-yl)phenylaminyls (2) were prepared by the reaction of the lithium salts of the corresponding anilines with tertbutyl peroxybenzoate. Although 1 could not be isolated as radical crystals, 2 was successfully obtained as red crystals. The X-ray crystallographic analysis and magnetic susceptibility measurements were performed for one isolated radical.