2,7-dimethylocta-1,7-diene-3,6-dione | 474304-48-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,7-dimethylocta-1,7-diene-3,6-dione
• 英文别名: 1,2-Dimethacryloylethane
• CAS: 474304-48-8
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: ZZFOSRAYCXZDSR-UHFFFAOYSA-N

物化性质

• 沸点：
  267.3±23.0 °C(Predicted)
• 密度：
  0.935±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,3:6,7-diepoxy-2,7-dimethyl-3,6-di(p-tolylsulfinyl)octane 在 sodium hydride 、 间氯过氧苯甲酸 作用下， 以 乙醇 、 二氯甲烷 、 甲苯 为溶剂， 反应 4.5h， 生成 2,7-dimethylocta-1,7-diene-3,6-dione
  参考文献：
  名称：

  A synthesis of diketones from carbonyl compounds and α,ω-dichloro-α,ω-disulfinylalkanes with two carbon–carbon bond-formation via bis-sulfinyloxiranes

  摘要：

  Bis-sulfinyloxiranes were synthesized in two steps from carbonyl compounds and alpha,omega-dichloro-alpha,omega-disulfinylalkanes, which were synthesized from alpha,omega-dibromoalkanes in three steps, in good yields. Treatment of the bis-sulfinyloxiranes with sodium benzenethiolate and piperidine gave alpha,alpha'-di(phenylthio) diketones and alpha,alpha'-diamino diketones, respectively, in high yields. From these products, some kinds of diketones were synthesized in good to high yields. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00352-6

文献信息

• Synthesis of α,ω‐Bis‐Enones by the Double Addition of Alkenyl Grignard Reagents to Diacid Weinreb Amides
  作者：Stefan Wiesler、Michael A. Bau、Thomas Niepel、Sara L. Younas、Hieu‐Trinh Luu、Jan Streuff

  DOI：10.1002/ejoc.201901043

  日期：2019.9.30

  The synthesis of bis‐enones from alkenyl bromides and α,ω‐bis‐Weinreb amides via a double Grignard reaction is reported. The work contains reliable protocols for the double addition and the efficient generation of the required substituted alkenyl Grignard reagents from alkenyl bromide precursors.

  据报道，通过双格氏反应由链烯基溴化物和α，ω-双-Weinreb酰胺合成双烯酮。这项工作包含可靠的协议，可以从烯基溴化物前体中进行双添加并有效生成所需的取代烯基格利雅试剂。
• Enhanced Enantioselectivity of Molecularly Imprinted Polymers Formulated with Novel Cross-Linking Monomers
  作者：Martha Sibrian-Vazquez、David A. Spivak

  DOI：10.1021/ma025710z

  日期：2003.7.1

  To enhance the performance of molecularly imprinted polymers (MlPs), three new cross-linking monomers were designed, synthesized, and evaluated as matrix elements for molecularly imprinted polymers. Hybrid cross-linking monomers incorporating methacrylamide/methacrylate (NOBE), vinyl ketone/methacrylamide (NAG), and vinyl ketone/methacrylate (MVK) polymerizable groups, were synthesized and used to prepare MIPs and compared to a traditional MIP formulated with EGDMA. The resulting macroporous MIPs were evaluated by HPLC for their ability to separate the enantiomers of a chiral template. The MIP formulated with the cross-linking monomer NAG showed the highest enantioselectivity and complete baseline resolution for a racemic mixture of the template. Enhancement in selectivity in this MIP may be attributed to the presence of the amide group which can promote hydrogen bonding via favorable 1,3 donor-acceptor interactions with the template, the morphology of the polymeric material obtained due to differences in reactivity between the polymerizable groups and improved resolution in cavity formation as a consequence of shorter cross-linker size.
• LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME
  申请人：DIC CORPORATION

  公开号：US20160230096A1

  公开（公告）日：2016-08-11

  A liquid crystal display device with few drop marks left during manufacture is provided without degrading the image-sticking characteristics of the liquid crystal display device or other characteristics fundamental to liquid crystal display devices, such as dielectric anisotropy, viscosity, upper nematic phase temperature limit, and rotational viscosity (γ 1 ), and a method for manufacturing such a liquid crystal display device is also provided. A liquid crystal display device 10 according to the present invention includes a first substrate 11 , a second substrate 12 , a liquid crystal composition layer 13 disposed therebetween, and vertical alignment layers 16 and 17 containing a polymer of a monofunctional reactive-group-containing polymerizable compound and a polyfunctional reactive-group-containing polymerizable compound.
• US8741291B2
  申请人：——

  公开号：US8741291B2

  公开（公告）日：2014-06-03
• A synthesis of diketones from carbonyl compounds and α,ω-dichloro-α,ω-disulfinylalkanes with two carbon–carbon bond-formation via bis-sulfinyloxiranes
  作者：Tsuyoshi Satoh、Daisaku Taguchi、Aki Kurabayashi、Makiko Kanoto

  DOI：10.1016/s0040-4020(02)00352-6

  日期：2002.5

  Bis-sulfinyloxiranes were synthesized in two steps from carbonyl compounds and alpha,omega-dichloro-alpha,omega-disulfinylalkanes, which were synthesized from alpha,omega-dibromoalkanes in three steps, in good yields. Treatment of the bis-sulfinyloxiranes with sodium benzenethiolate and piperidine gave alpha,alpha'-di(phenylthio) diketones and alpha,alpha'-diamino diketones, respectively, in high yields. From these products, some kinds of diketones were synthesized in good to high yields. (C) 2002 Elsevier Science Ltd. All rights reserved.