4-O-n-dodecylbutan-1-ol | 112570-39-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-O-n-dodecylbutan-1-ol
• 英文别名: 5-Oxaheptadecanol-1；4-dodecyloxy-butan-1-ol；4-Dodecoxybutan-1-ol
• CAS: 112570-39-5
• 化学式: C₁₆H₃₄O₂
• 分子量: 258.445
• InChiKey: HLSOYQHAXQXBHT-UHFFFAOYSA-N

物化性质

• 沸点：
  339.7±10.0 °C(Predicted)
• 密度：
  0.871±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-O-n-dodecylbutan-1-ol 在 4-二甲氨基吡啶 、 potassium hydroxide 作用下， 以 二氯甲烷 、 二甲基亚砜 、 甲苯 为溶剂， 反应 23.0h， 生成 6-O-(4-O-n-dodecylbut-1-yl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose
  参考文献：
  名称：

  Synthesis, surface tension properties and antibacterial activities of amphiphilic d -galactopyranose derivatives

  摘要：

  Several amphiphilic D-galactopyranose derivatives were synthesized in which the glycosidic moiety was separated from the hydrophobic alkyl chain (along 8 or 12 carbon atoms) by a spacer arm (butyl, butynyl or benzyl) in order to increase their surfactant properties and to obtain new antibacterial compounds. The surface tensions of the products were analyzed by Critical Micelle Concentration (CMC) and gamma(CMC) measurements and the antimicrobial activities were assayed against 10 bacterial species by Minimum Inhibitory Concentration (MIC) determination in liquid broth. The introduction of an aliphatic spacer arm increased the amphiphilic properties of the compounds and the CMC values were 40-500 times lower than their analogs without spacer arm. In the same manner, the spacer arms significantly increased the antibacterial power of the compounds. The products 4d and 4e exhibiting a C12 alkyl chain and an aliphatic spacer arm (butyl and butynyl) were the best surfactants (CMC = 0.023 and 0.032 mmol/L, respectively) and presented also the best antibacterial activities (MIC = 15.62 and 3.91 mu g/mL for Micrococcus luteus, respectively). But the antibacterial activity of the newly synthesized products seemed to depend more on the cell wall composition of the bacteria than only on the amphiphilic character of the compounds. (C) 2012 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2012.12.032
• 作为产物：
  描述：

  2-Dodecyloxy-tetrahydro-furan 在 二甲基溴化硼 、 三乙基硼氢化锂 作用下， 以 二氯甲烷 为溶剂， 以67%的产率得到4-O-n-dodecylbutan-1-ol
  参考文献：
  名称：

  使用二甲基溴化硼对THP和THF醚进行环裂解

  摘要：

  研究了溴化二甲基硼与THP和THF醚的反应。在动力学控制的条件下，这些反应通过选择性裂解环碳-氧键进行，得到无环α-溴醚。用各种亲核试剂处理这些中间体可得到开环产物。

  DOI：

  10.1016/s0040-4039(00)96086-6

文献信息

• LIPOPHILIC, HIGHLY BRANCHED POLYMER, AND PHOTOPOLYMERIZABLE COMPOSITION CONTAINING THE SAME
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2687549A1

  公开（公告）日：2014-01-22

  There is provided a highly branched lipophilic polymer that is excellent in blending and dispersing properties in a matrix resin, and is possible to provide surface modification properties such as excellent lipophilicity (anti-fingerprint property) and the like to a coating that is obtained from the resin composition while the intrinsic transparency of the resin is not impaired; and a photopolymeizable composition comprising the highly branched lipophilic polymer. A highly branched lipophilic polymer obtained by polymerizing a monomer A containing two or more radically polymerizable double bonds per molecule and a monomer B containing a C6-30 alkyl group or a C3-30 alicyclic group and at least one radically polymerizable double bond per molecule in the presence of 5 to 200 mol% of a polymerization initiator C relative to the number of moles of the monomer A. A photopolymeizable composition comprising the highly branched lipophilic polymer.

  本发明提供了一种高支化亲脂性聚合物，该聚合物在基体树脂中具有优异的混合性和分散性，并且可以在不影响树脂固有透明度的情况下，为从树脂组合物中获得的涂层提供优异的亲脂性（抗指纹性）等表面改性特性；以及一种包含该高支化亲脂性聚合物的可光渗透组合物。一种高支化亲脂性聚合物，它是由每分子含有两个或两个以上可辐射聚合双键的单体 A 和每分子含有 C6-30 烷基或 C3-30 脂环基和至少一个可辐射聚合双键的单体 B 在聚合引发剂 C（相对于单体 A 的摩尔数）为 5 至 200 摩尔的存在下聚合而成。
• HIGHLY BRANCHED LIPOPHILIC POLYMER, AND PHOTOPOLYMERIZABLE COMPOSITION CONTAINING THE SAME
  申请人：Matsuyama Motonobu

  公开号：US20140088216A1

  公开（公告）日：2014-03-27

  There is provided a highly branched lipophilic polymer that is excellent in blending and dispersing properties in a matrix resin, and is possible to provide surface modification properties such as excellent lipophilicity (anti-fingerprint property) and the like to a coating that is obtained from the resin composition while the intrinsic transparency of the resin is not impaired; and a photopolymeizable composition comprising the highly branched lipophilic polymer. A highly branched lipophilic polymer obtained by polymerizing a monomer A containing two or more radically polymerizable double bonds per molecule and a monomer B containing a C 6-30 alkyl group or a C 3-30 alicyclic group and at least one radically polymerizable double bond per molecule in the presence of 5 to 200 mol % of a polymerization initiator C relative to the number of moles of the monomer A. A photopolymeizable composition comprising the highly branched lipophilic polymer.
• US4408084A
  申请人：——

  公开号：US4408084A

  公开（公告）日：1983-10-04
• US9334400B2
  申请人：——

  公开号：US9334400B2

  公开（公告）日：2016-05-10
• US9708486B2
  申请人：——

  公开号：US9708486B2

  公开（公告）日：2017-07-18