2-(乙烯氧基)乙胺 | 7336-29-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-(乙烯氧基)乙胺
• 中文别名: 3-乙烯氧基丙胺；2-氨基乙基乙烯基醚
• 英文名称: 2-aminoethyl vinyl ether
• 英文别名: monoethanolamine vinyl ether；2-vinyloxyethylamine；2-(Vinyloxy)ethanamine；2-ethenoxyethanamine
• CAS: 7336-29-0
• 化学式: C₄H₉NO
• mdl: MFCD01862888
• 分子量: 87.1216
• InChiKey: CEYHHQSTMVVZQP-UHFFFAOYSA-N

物化性质

• 沸点：
  113-116 °C(lit.)
• 密度：
  0.908 g/mL at 20 °C(lit.)
• 闪点：
  29 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  6
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xn
• 安全说明：
  S16,S26,S33,S36
• 危险类别码：
  R20/21/22,R34,R36/37

反应信息

• 作为反应物：
  描述：

  2-(乙烯氧基)乙胺 在 mercury(II) diacetate 作用下， 以 various solvent(s) 为溶剂， 以48%的产率得到2-甲基-1,3-恶唑烷
  参考文献：
  名称：

  恶唑烷。2.通过1，2-氨基醇的乙烯基醚的环化合成2-甲基恶唑烷

  摘要：

  DOI：

  10.1007/bf00542787
• 作为产物：
  描述：

  [1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-(2-vinyloxy-ethyl)-amine 在 水 作用下， 生成 2-(乙烯氧基)乙胺
  参考文献：
  名称：

  Reaction of monoethanolamine vinyl ether with aldehydes

  摘要：

  DOI：

  10.1007/bf00929034

文献信息

• Four-Component Reaction between Secondary Phosphines, Primary Amines, Aldehydes, and Chalcogens: A Facile Access to Functionalized α-Aminophosphine Chalcogenides
  作者：Boris Trofimov、Alexander Artem’ev、Nikita Kolyvanov、Ludmila Oparina、Nina Gusarova、Anastasiya Sutyrina、Irina Bagryanskaya

  DOI：10.1055/s-0036-1588127

  日期：——

  original four-component reaction between secondary phosphines, primary amines, aldehydes, and elemental sulfur or selenium occurs chemoselectively under mild conditions (60 °C, benzene, 3–9 h) to afford the hitherto unknown functionalized α-aminophosphine sulfides and selenides in good to excellent yields. The original four-component reaction between secondary phosphines, primary amines, aldehydes, and elemental

  摘要 仲膦，伯胺，醛和元素硫或硒之间的原始四组分反应在温和条件（60°C，苯，3–9 h）下发生化学选择性，从而提供了迄今未知的官能化α-氨基膦硫化物和硒化物好到极好的产量。 仲膦，伯胺，醛和元素硫或硒之间的原始四组分反应在温和条件（60°C，苯，3–9 h）下发生化学选择性，从而提供了迄今未知的官能化α-氨基膦硫化物和硒化物好到极好的产量。
• [EN] CLEAVABLE NUCLEOTIDE ANALOGS AND USES THEREOF<br/>[FR] ANALOGUES NUCLÉOTIDIQUES CLIVABLES ET LEURS UTILISATIONS
  申请人：HARVARD COLLEGE

  公开号：WO2018102554A1

  公开（公告）日：2018-06-07

  Cleavable nucleotide analogs are provided. The nucleotide analog includes a nucleotide molecule attached to a cleavable moiety wherein the cleavable moiety comprises a protective group and/or a linker attached to a fluorophore. The cleavable moiety is linked to the oxygen atom of the 3'-OH of the pentose of the nucleotide molecule. The nucleotide analogs can be used in making polynucleotide molecules using template independent polymerases. The nucleotide analogs can act as reversible terminators during DNA sequencing by synthesis. The cleavage of the cleavable moiety restores a free 3'-OH functional group allowing growth of the polynucleotide molecule. The general structures as well as proposed synthetic schemes for the nucleotide analogs are also provided.

  可切割的核苷酸类似物已提供。该核苷酸类似物包括连接到可切割基团的核苷酸分子，其中可切割基团包括保护基团和/或连接到荧光团的连接物。可切割基团连接到核苷酸分子的五碳糖的3'-OH的氧原子。这些核苷酸类似物可用于使用模板无关聚合酶制备多核苷酸分子。这些核苷酸类似物在DNA合成测序过程中可作为可逆终止子。切割可切割基团恢复自由的3'-OH官能团，从而促进多核苷酸分子的生长。还提供了核苷酸类似物的一般结构以及拟议的合成方案。
• Liquid core capsules and methods of synthesis thereof through interfacial polymerization
  申请人：Wu Dan

  公开号：US20060127490A1

  公开（公告）日：2006-06-15

  A process for the encapsulation of liquid particles within nanometer thick polymer shells utilizes an interfacial free radical alternating copolymerization process. Encapsulating a liquid material includes providing a mixture comprising the liquid material to be encapsulated, a hydrophobic monomer in a non-polar solution and a hydrophilic monomer in a polar solution. The liquid material is compatible in either the polar solution or the non-polar solution. The polar solution and the non-polar solution are not miscible in each other. The mixture is homogenized to form an emulsion, and then polymerized by an initiator which initiates an interfacial free radical alternating copolymerization process. The copolymerization process is optimally constrained to proceed only at the hydrophobic and hydrophilic interface thus forming a polymer around the liquid material.

  一种用于在纳米厚度聚合物壳内封装液体颗粒的过程利用界面自由基交替共聚合过程。封装液体材料包括提供包括待封装的液体材料、疏水单体在非极性溶液中和亲水单体在极性溶液中的混合物。液体材料与极性溶液或非极性溶液中的任一种兼容。极性溶液和非极性溶液在彼此中不互溶。混合物经均质化形成乳液，然后由引发剂聚合，引发界面自由基交替共聚合过程。共聚合过程在最佳条件下仅受限于在疏水和亲水界面进行，从而形成液体材料周围的聚合物。
• Condensation of 2- and 4-fluorobenzaldehydes with vinyl ethers derived from amino alcohols
  作者：B. F. Kukharev、V. K. Stankevich、E. Kh. Sadykov、G. R. Klimenko

  DOI：10.1134/s1070428011120074

  日期：2011.12

  2- and 4-Fluorobenzaldehydes reacted with amino alcohol vinyl ethers to give Schiff bases, oxazolidines, and imidazolidines containing a vinyloxy group. The products attract interest as potential biologically active compounds.

  2-和4-氟苯甲醛与氨基醇乙烯基醚反应生成席夫碱，恶唑烷和含乙烯基氧基的咪唑烷。该产品作为潜在的生物活性化合物引起了人们的兴趣。
• Unsaturated thioureido ethers, polymers thereof and process of making them
  申请人：ROHM &

  公开号：US02858295A1

  公开（公告）日：1958-10-28

  Compounds of formula CH2=C(R)COO-A-NH-CO-NH2 wherein R is hydrogen or a methyl group and A represents a saturated, divalent, aliphatic or cycloaliphatic hydrocarbon group, may be polymerized or copolymerized with compounds containing at least one vinylidene group. A is preferably an alkylene group containing 2-14 carbon atoms, e.g. an ethylene, propylene or trimethylene group. The polymerization can be carried out in bulk or in solution or emulsion, and may be accelerated by the use of heat, ultraviolet light and free-radical catalysts, e.g. a : a1 - bis - azoisobutyronitrile, methyl azoisobutyrate, ascaridol, tertiary-butyl and cumene hydroperoxides, benzoyl, acetyl, lauroyl, ditertiary-butyl and stearyl peroxides, tertiary-butyl perbenzoate and "per salts" such as ammonium persulphate and ammonium perborate. Specified vinylidene compounds are N-dialkyl acrylamides, e.g. dimethyl and diethyl acrylamide; esters of acrylic, methacrylic and a-chloroacrylic acids, e.g. methyl, ethyl, butyl, octyl and 2-ethylhexyl acrylate, methyl, tertiary-butyl and octyl methacrylate; butyl and lauryl chloroacrylate; vinyl hydrocarbons, e.g. styrene, a-methylstyrene, vinylnaphthalene, vinyltoluene, di- and trivinylbenzene; vinyl and vinylidene chloride; diallyl phthalate and allyl and methallyl esters of saturated aliphatic carboxylic acids, e.g. allyl acetate and methallyl propionate; acrylonitrile and vinylpyridine. Specified ureido esters are b-ureidoethyl acrylate and methacrylate. At least 1 per cent molar and preferably 2-20 per cent of ureido ester is used in the preparation of copolymers. In an example beta-ureidoethyl acrylate and methacrylate are copolymerized with ethyl, butyl and octyl acrylates in an aqueous emulsion containing tert.-octylphenoxypolyethoxyethanol as a dispersing agent and a mixture of ammonium persulphate and sodium hydrosulphite as a catalyst. The copolymer emulsions produced are used in the shrink-proofing of woolen fabric. Specification 759,860 is referred to. ALSO: The invention comprises compounds of formula CH2 = C(R)COO-A-NH-CO-NH2 wherein R represents hydrogen or a methyl group and A represents a saturated, divalent, aliphatic or cycloaliphatic hydrocarbon group preferably containing 2-14 carbon atoms, e.g. ethylene, propylene and trimethylene. The compounds are prepared by reacting ammonia with a isocyanato ester of acrylic or methacrylic acid having the formula CH2 = C(R)COO-A-NCO The reaction is conducted at temperatures of 0-50 DEG C. and preferably in presence of an inert solvent. The examples describe the preparation of b-ureidoethyl acrylate and methacrylate. Specification 759,860 is referred to. ALSO: Woollen fabrics are shrink-proofed by padding them with an aqueous emulsion of a copolymer comprising at least 1 per cent (on a molar basis) of a copolymerized ureido ester of formula:-CH2=C(R)COO-A-NH-CO-NH2 wherein R is hydrogen or a methyl group and A is a saturated, divalent, aliphatic or cycloaliphatic hydrocarbon group, and at most 99 per cent of a copolymerized compound containing a vinyl or vinylidene group, and heating the treated fabric to at least 240 DEG F. Specified vinyl or vinyliden compounds are N-dialkyl acrylamides, e.g. dimethyl and diethyl acrylamide; esters of acrylic, methacrylic and a-chloroacrylic acids, e.g. methyl, ethyl, butyl, octyl or 2 - ethyhexyl acrylate, methyl, tertiary-butyl or octyl methacrylate, or butyl or lauryl chloroacrylate; vinyl hydrocarbons, e.g. styrene, a-methylstyrene, vinylnaphthalene, vinyltoluene or di- and trivinylbenzene; vinyl and vinylidene chloride; diallylphthalate and allyl and methallyl esters of saturated aliphatic carboxylic acids, e.g. allyl acetate or methallyl propionate; acrylonitrile and vinylpyridine. Specified ureido esters are b-ureidoethylacrylate and methacrylate. Specification 759,860 is referred to.

  化学式为CH2=C(R)COO-A-NH-CO-NH2的化合物中，其中R为氢或甲基基团，A代表饱和的、二价的、脂肪族或环脂族碳氢基团，可以与含有至少一个乙烯基团的化合物聚合或共聚。 A最好是含有2-14个碳原子的烷基基团，例如乙烯基、丙烯基或三甲基基团。聚合可以在块状、溶液或乳液中进行，并且可以通过使用热量、紫外线和自由基催化剂加速，例如双(2-氰基)丙酰二(2-氰基)丙烯酰胺、丙烯酸异丁酯、阿斯卡里酮、叔丁基过氧化氢和叔丁基烯基过氧化氢、苯甲酰、乙酰、月桂酰、双叔丁基过氧化氢和硬脂酰过氧化氢、叔丁基过苯甲酸酯和过盐，如过硫酸铵和过硼酸铵。指定的乙烯基化合物包括N-二烷基丙烯酰胺，例如二甲基丙烯酰胺和二乙基丙烯酰胺；丙烯酸、甲基丙烯酸和α-氯丙烯酸的酯类，例如甲基丙烯酸酯、乙基丙烯酸酯、丁基丙烯酸酯、辛基丙烯酸酯和2-乙基己基丙烯酸酯、甲基、叔丁基和辛基甲基丙烯酸酯；丙烯酸丁酯和月桂基氯丙烯酸酯；乙烯烃类化合物，例如苯乙烯、α-甲基苯乙烯、乙烯基萘、乙烯基甲苯、二乙烯基苯和三乙烯基苯；乙烯基和乙烯基氯；邻苯二甲酸二烯丙酯和饱和脂族羧酸醇酯的烯丙基和甲基烯丙基酯，例如丙烯酸烯丙酯和丙烯酸丙酯；丙烯腈和乙烯吡啶。指定的尿素酯是β-尿素乙基丙烯酸酯和甲基丙烯酸酯。在共聚物的制备中至少使用1摩尔百分比，最好是2-20摩尔百分比的尿素酯。在一个示例中，β-尿素乙基丙烯酸酯和甲基丙烯酸酯与乙酸、丁酸和辛酸丙烯酸酯在含有叔辛基酚聚乙氧乙醇作为分散剂和过硫酸铵和亚硫酸氢钠混合物作为催化剂的水乳液中共聚。生产的共聚物乳液用于羊毛织物的防缩处理。参考规范759,860。 此外：该发明涉及化学式为CH2 = C(R)COO-A-NH-CO-NH2的化合物，其中R代表氢或甲基基团，A代表饱和的、二价的、脂肪族或环脂族碳氢基团，最好含有2-14个碳原子，例如乙烯、丙烯和三甲基基团。这些化合物是通过将氨与丙烯酸或甲基丙烯酸的异氰酸酯反应制备的，其化学式为CH2 = C(R)COO-A-NCO。反应在0-50摄氏度的温度下进行，最好在惰性溶剂的存在下进行。示例描述了β-尿素乙基丙烯酸酯和甲基丙烯酸酯的制备。参考规范759,860。 此外：羊毛织物通过使用至少含有1%（以摩尔基础计）共聚化的尿素酯乳液进行填料处理，其中尿素酯的化学式为-CH2=C(R)COO-A-NH-CO-NH2，其中R为氢或甲基基团，A为饱和的、二价的、脂肪族或环脂族碳氢基团，最多含有99%的共聚化合物，其中包含乙烯基或乙烯基基团，然后将处理过的织物加热至至少240华氏度。指定的乙烯或乙烯基化合物包括N-二烷基丙烯酰胺，例如二甲基丙烯酰胺和二乙基丙烯酰胺；丙烯酸、甲基丙烯酸和α-氯丙烯酸的酯类，例如甲基丙烯酸酯、乙基丙烯酸酯、丁基丙烯酸酯、辛基丙烯酸酯和2-乙基己基丙烯酸酯、甲基、叔丁基和辛基甲基丙烯酸酯，或丁基或月桂基氯丙烯酸酯；乙烯烃类化合物，例如苯乙烯、α-甲基苯乙烯、乙烯基萘、乙烯基甲苯或二-和三乙烯基苯；乙烯和乙烯基氯；邻苯二甲酸二烯丙酯和饱和脂族羧酸醇酯的烯丙基和甲基烯丙基酯，例如丙烯酸烯丙酯和丙烯酸丙酯；丙烯腈和乙烯吡啶。指定的尿素酯是β-尿素乙基丙烯酸酯和甲基丙烯酸酯。参考规范759,860。