2,5-bis[2-(4-methoxyphenyl)ethenyl]pyrazine | 102441-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,5-bis[2-(4-methoxyphenyl)ethenyl]pyrazine
• 英文别名: 2,5-bis(4-methoxystyryl)pyrazine；2,5-bis-(4-methoxy-styryl)-pyrazine；2,5-Bis-(4-methoxy-styryl)-pyrazin；2,5-bis[(E)-2-(4-methoxyphenyl)ethenyl]pyrazine
• CAS: 102441-65-6
• 化学式: C₂₂H₂₀N₂O₂
• 分子量: 344.413
• InChiKey: ZGXQLVRLPJXTIK-LQIBPGRFSA-N

物化性质

• 沸点：
  525.7±38.0 °C(Predicted)
• 密度：
  1.186±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  44.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,5-二甲基吡嗪 、 4-甲氧基苯甲醛 在 sodium hydroxide 、 四丁基硫酸氢铵 作用下， 反应 3.0h， 以20%的产率得到2,5-bis[2-(4-methoxyphenyl)ethenyl]pyrazine
  参考文献：
  名称：

  季铵盐辅助合成来自甲基二嗪和芳香醛的扩展 π 系统1

  摘要：

  4-甲基-和4,6-二甲基嘧啶、甲基-和2,5-二甲基吡嗪以及3-甲基哒嗪在催化量的季铵盐存在下，在氢氧化钠的热溶液中很容易与芳香醛反应并且在不存在任何有机溶剂的情况下产生相应的缩合产物。

  DOI：

  10.1081/scc-100105893

文献信息

• COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM
  申请人：Schmidt Boris

  公开号：US20130287700A1

  公开（公告）日：2013-10-31

  Subject of the present invention are compounds with high affinity for the Aβ protein, α-synuclein or for Tau-PHF aggregates, which are suitable as preferably fluorescent probes for the in vivo diagnosis of neurodegenerative disorders like e.g. Alzheimer's disease and Parkinson's disease. The compounds are characterized by suitable physicochemical properties (excitation wavelength, emission wavelength, Stokes shift, extinction) as well as a high affinity and selectivity for the target proteins.

  本发明的主题是具有高亲和力的化合物，用于Aβ蛋白、α-突触核蛋白或Tau-PHF聚集物，适用于作为体内诊断神经退行性疾病（如阿尔茨海默病和帕金森病）的首选荧光探针。这些化合物具有适当的物理化学性质（激发波长、发射波长、斯托克斯位移、消光），以及对目标蛋白的高亲和力和选择性。
• Silanamine derivative and process for the production thereof, and organical EL device using the said silanamine derivative
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0563811A1

  公开（公告）日：1993-10-06

  Silanamine derivatives which have the formula (I),    wherein each of Ar¹s and Ar³s is an optionally substituted aryl group and Ar² is an optionally substituted arylene group, and which are used as a material for producing an organic EL device.

  具有公式（I）的Silanamine衍生物，其中Ar¹s和Ar³s各自是可选取代的芳基基团，Ar²是可选取代的芳烃基团，并且用作制造有机EL器件的材料。
• A New Series of Electroluminescent Organic Compounds
  作者：Masao Nohara、Masaki Hasegawa、Chishio Hosokawa、Hiroshi Tokailin、Tadashi Kusumoto

  DOI：10.1246/cl.1990.189

  日期：1990.2

  A new series of electroluminescent organic compounds, 2,5-distyrylpyrazine derivatives, were prepared and investigated on EL properties. The high brightness was achieved in some of these compounds at a low dc voltage of about 10 V.

  制备了一系列新的电致发光有机化合物 2,5-二苯乙烯基吡嗪衍生物并研究了 EL 特性。其中一些化合物在约 10 V 的低直流电压下实现了高亮度。
• ORGANIC ELECTROLUMINESCENT ELEMENT AND ARYLENEDIAMINE DERIVATIVE
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0721935A1

  公开（公告）日：1996-07-17

  Organic electroluminescence devices having the life of light emission superior to those of conventional electroluminescence devices, and novel arylenediamine derivatives which can remarkably improve the life of light emission of an organic electroluminescence device when the derivatives are used as a component of the device, are disclosed. The organic electroluminescence devices of the present invention at least contain a p-phenylenediamine derivative having 6 or more benzene ring skeletons, or at least a 4,4'-biphenylenediamine derivative having 5 biphenyl groups. The arylenediamine derivatives of the present invention include p-phenylenediamine derivatives having 4 biphenyl groups and 4,4'-biphenylenediamine derivatives having 5 biphenyl groups.

  本发明公开了发光寿命优于传统电致发光器件的有机电致发光器件，以及新型芳基二胺衍生物，当该衍生物用作有机电致发光器件的组件时，可显著提高该器件的发光寿命。 本发明的有机电致发光器件至少含有一种具有 6 个或更多苯环骨架的对苯二胺衍生物，或至少含有一种具有 5 个联苯基团的 4,4'-联苯二胺衍生物。 本发明的芳基二胺衍生物包括具有 4 个联苯基团的对苯二胺衍生物和具有 5 个联苯基团的 4,4'-联苯二胺衍生物。
• Acrylenediamine derivatives and organic electroluminescence device containing the same
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP1162193A1

  公开（公告）日：2001-12-12

  Organic electroluminescence devices having the life of light emission superior to those of conventional electroluminescence devices, and novel arylenediamine derivatives which can remarkably improve the life of light emission of an organic electroluminescence device when the derivatives are used as a component of the device, are disclosed. The organic electroluminescence devices of the present invention at least contain a 4,4'-biphenylenediamine derivative having 5 biphenyl groups. The arylenediamine derivatives of the present invention include 4,4'-biphenylenediamine derivatives having 5 biphenyl groups.

  本发明公开了发光寿命优于传统电致发光器件的有机电致发光器件，以及新型芳基二胺衍生物，当该衍生物用作有机电致发光器件的组成部分时，可显著提高该器件的发光寿命。 本发明的有机电致发光器件至少含有一种具有 5 个联苯基团的 4,4'-联苯二胺衍生物。 本发明的芳基二胺衍生物包括具有 5 个联苯基团的 4,4'-联苯二胺衍生物。