1,3-bis(n-octylthio)-2-propanol | 32338-88-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3-bis(n-octylthio)-2-propanol
• 英文别名: 1,3-bis-octylsulfanyl-propan-2-ol；1,3-Bis(octylsulfanyl)-2-propanol；1,3-bis(octylsulfanyl)propan-2-ol
• CAS: 32338-88-8
• 化学式: C₁₉H₄₀OS₂
• 分子量: 348.658
• InChiKey: JRVSMEUYHGMMSU-UHFFFAOYSA-N

物化性质

• 沸点：
  472.4±30.0 °C(Predicted)
• 密度：
  0.947±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  70.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-溴-3-氯-2-丙醇 、 1-辛硫醇 生成 1,3-bis(n-octylthio)-2-propanol
  参考文献：
  名称：

  Study of some?-hydroxyalkyl sulfides and bis-(?-hydroxyalkyl) disulfides

  摘要：

  DOI：

  10.1007/bf00930049

文献信息

• Sulfoxides or sulfones grafted onto polymers
  申请人：——

  公开号：US20040152836A1

  公开（公告）日：2004-08-05

  Polymers grafted with a compound of formula I, formula (I) wherein the general symbols are as defined in claim 1, have outstanding stability against oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation. [R 1 13 SO m &Brketclosest; n —R—SO p —R 2 (I)

  用式(I)化合物接枝的聚合物，式(I)中的通式符号如权利要求 1 所定义，对氧化、热、动态、光诱导和/或臭氧诱导的降解具有出色的稳定性。 [R 1 13 SO m &Brketclosest； n -R-SO p -R 2 (I)
• The reaction of thiolates with 2,3-dibromo-1-propanol revisited: application to the synthesis of bis(fattyalkylthio)propanols
  作者：Michael D Gernon、Joseph G Turcotte、Robert H Notter、Min Wu、Yvonne Lear、Jennifer L Snelgrove、Adrian L Schwan

  DOI：10.1016/s0009-3084(99)00048-1

  日期：1999.9

  This work compares two reaction schemes for preparing 2,3-bis(fattyalkylthio)-1-propanols for further synthetic adaptation as hydrophobic analogs of lung surfactant phosphatidylcholines. An attempt to prepare 2,3-bis(fattyalkylthio)-1-propanols based on the previously published methods of Bell and co-workers (B.R. Ganong, C.R. Loomis, Y.A. Hannun, R.M. Bell, 1986. Proc. Natl. Acad. Sci. USA 83, 1184-1188; B.R. Ganong, R.M. Bell, 1987. Methods Enzymol. 141, 313-320; J.P. Walsh, L. Fahrner, R.M. Bell, 1990. J. Biol. Chem. 265, 4374-4381) was found to give the rearranged 1,3-bis(fattyalkylthio)-2-propanols as major products. As a reliable alternative, the reaction of ethyl 2,3-dibromopropionate with 2 equivalents of long chain sodium n-alkanethioates gave the corresponding ethyl 2,3-bis(n-alkylthio)propionates, which were then reduced with LiAlH4 to yield the desired 2,3-bis(fattyalkylthio)-1-propanols. Both 13C and 1H NMR spectroscopy were used to differentiate the two possible 1,3- and 2,3-dithio substituted alcohol products and to rigorously assign their structures.
• NIYAZYMBETOV, M. E.;KONYUSHKIN, L. D.;NIYAZYMBETOVA, Z. I.;LITVINOV, V. P+, IZV. AN CCCP. CEP. XIM.,(1990) N0, S. 2459-2460
  作者：NIYAZYMBETOV, M. E.、KONYUSHKIN, L. D.、NIYAZYMBETOVA, Z. I.、LITVINOV, V. P+

  DOI：——

  日期：——
• SULFOXIDES OR SULFONES GRAFTED ONTO POLYMERS
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1373196A2

  公开（公告）日：2004-01-02
• US7160955B2
  申请人：——

  公开号：US7160955B2

  公开（公告）日：2007-01-09