2-[(2R,3S,4S,5R,6S)-3,4,5,6-四羟基四氢吡喃-2-基]乙酸 | 34980-72-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-[(2R,3S,4S,5R,6S)-3,4,5,6-四羟基四氢吡喃-2-基]乙酸
• 英文名称: 6-Desoxy-α-D-gluco-hepturonsaeure
• 英文别名: α-D-gluco-6-deoxy-heptopyranuronic acid；α-D-gluco-6-Desoxy-heptopyranuronsaeure；6-Deoxy-alpha-gluco-heptopyranosyluronic acid；2-[(2R,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]acetic acid
• CAS: 34980-72-8
• 化学式: C₇H₁₂O₇
• 分子量: 208.168
• InChiKey: BZZCQGGHDQIPST-VCPFRWQBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  127
• 氢给体数：
  5
• 氢受体数：
  7

安全信息

• 海关编码：
  2932999099

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 硫酸 作用下， 生成 2-[(2R,3S,4S,5R,6S)-3,4,5,6-四羟基四氢吡喃-2-基]乙酸
  参考文献：
  名称：

  Zur darstellung der 6-desoxy-hepturons�ure

  摘要：

  DOI：

  10.1007/bf00898756

文献信息

• [EN] MIRROR AMIDE CORD FACTORS AND MIRROR THIOESTER CORD FACTORS FOR DIAGNOSIS OF TUBERCULOSIS<br/>[FR] ANALOGUES DE DIMYCOLATE-6,6' DE TREHALOSE D'AMIDE ET DE THIOESTER EN MIROIR, DESTINES AU DIAGNOSTIC DE LA TUBERCULOSE
  申请人：INFLAZYME PHARMACEUTICALS CANADA INC.

  公开号：WO1994022884A1

  公开（公告）日：1994-10-13

  (EN) A 'mirror' amide cord factor of 'mirror' thioester cord factor having generic formula (I) wherein T is nitrogen or sulphur and when T is nitrogen, R1 is an alkyl or alkoxy having 8 to 90 carbon atoms, 11 to 191 hydrogen atoms, and 0 to 10 oxygens, and R2 is hydrogen or the same as R1; and when T is sulphur, R1 is an alkyl or alkoxy group having 8 to 90 carbons, 11 to 181 hydrogens, 0 to 10 oxygens, and R2 is absent.(FR) On décrit un analogue de dimycolate-6,6' de tréhalose d'amide ou de thioester en miroir correspondant à la formule générale (I) où T représente azote ou soufre et, quand T représente azote, R1 représente un groupe alkyle ou alcoxy doté de 8 à 90 atomes de carbone, 11 à 191 atomes d'hydrogène et 0 à 10 atomes d'oxygène, et R2 représente hydrogène ou équivaut à R1; et, quand T représente soufre, R1 représente un groupe alkyle ou alcoxy doté de 8 à 90 atomes de carbone, 11 à 181 atomes d'hydrogène, 0 à 10 atomes d'oxygène, et R2 est absent.

  这是一个涉及镜像酰胺和镜像 thiostère 的化合物的翻译，符合具体的分子式和结构描述： (I) 其中 T 代表氮或硫。当 T 为氮时，R1为烷基或氧基，含 8 到 90 个碳原子，11 到 191 个氢原子，0 到 10 个氧原子，R2为氢或与 R1 相同；当 T 为硫时，R1为烷基或氧基，含8 到 90 个碳原子，11 到 181 个氢原子，0 到 10 个氧原子，R2为无。 (FR) 该化合物的法文本意为：它是镜像二糖的酰胺或 thiostère类化合物，对应通用分子式 (I)，其中 T 代表氮或硫。如T为氮，则R1为烷基或氧基，含 8至90 个碳原子，11至191 个氢原子，0至10 个氧原子，R2为氢或与 R1相同；若 T为硫，则R1为烷基或氧基，含8至90 个碳原子，11至181 个氢原子，0至10 个氧原子，R2为无。
• Capon; Walker, Journal of the Chemical Society. Perkin transactions I, vol. II, p. 1974,1600, 1608, 1609
  作者：Capon、Walker

  DOI：——

  日期：——
• Noninterfering Multipurpose Compositions for Collecting, Transporting and Storing Biological Samples
  申请人：Longhorn Vaccines and Diagnostics, LLC

  公开号：US20140186821A1

  公开（公告）日：2014-07-03

  The invention is directed to compositions and methods for collecting, transporting, and storing microorganisms obtained from samples of biological, clinical, forensic, and environmental origin. Compositions preserve the viability of the collected organisms, permit long-term storage, and are compatible with subsequent manipulation including propagation and culture of collected microorganisms, or isolation, purification, detection, and characterization of proteins, nucleic acids and macromolecules. When the compositions containing microorganisms and polynucleotides therein are further processed, such as by nucleic acid testing, there is an increased ability to detect, isolate, purify and/or characterize select microbes and their components, when compared to conventional microbial transport media that contain interfering substance(s). In particular formulations, the compositions allow biological samples to be collected, transported, and even stored for extended periods, and are compatible with nucleic acid extraction, identification, quantitation, PCR amplification, and genomic analysis methodologies.
• US5399683A
  申请人：——

  公开号：US5399683A

  公开（公告）日：1995-03-21
• [EN] NONINTERFERING MULTIPURPOSE COMPOSITIONS FOR COLLECTING, TRANSPORTING AND STORING BIOLOGICAL SAMPLES<br/>[FR] COMPOSITIONS POLYVALENTES SANS INTERFÉRENCE POUR LA COLLECTE, LE TRANSPORT ET LE STOCKAGE D'ÉCHANTILLONS BIOLOGIQUES
  申请人：LONGHORN VACCINES & DIAGNOSTICS LLC

  公开号：WO2014105722A1

  公开（公告）日：2014-07-03

  The invention is directed to compositions and methods for collecting, transporting, and storing microorganisms obtained from samples of biological, clinical, forensic, and environmental origin. Compositions preserve the viability of the collected organisms, permit long-term storage, and are compatible with subsequent manipulation including propagation and culture of collected microorganisms, or isolation, purification, detection, and characterization of proteins, nucleic acids and macromolecules. When the compositions containing microorganisms and polynucleotides therein are further processed, such as by nucleic acid testing, there is an increased ability to detect, isolate, purify and/or characterize select microbes and their components, when compared to conventional microbial transport media that contain interfering substance(s). In particular formulations, the compositions allow biological samples to be collected, transported, and even stored for extended periods, and are compatible with nucleic acid extraction, identification, quantitation, PCR amplification, and genomic analysis methodologies.