2-methyl-6-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl)imidazo[1,2-a]pyrazin-3(7H)-one | 1262331-11-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-methyl-6-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl)imidazo[1,2-a]pyrazin-3(7H)-one
• 英文别名: 6-(1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one
• CAS: 1262331-11-2
• 化学式: C₁₉H₂₀N₄O
• 分子量: 320.394
• InChiKey: BOKZPUHBJBGAFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.67
• 重原子数：
  24.0
• 可旋转键数：
  1.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  53.92
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  1,1-二甲氧基丙酮 、 2-amino-5-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl)pyrazine hydrochloride 以 1,4-二氧六环 、 水 为溶剂， 反应 240.0h， 以12%的产率得到2-methyl-6-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl)imidazo[1,2-a]pyrazin-3(7H)-one
  参考文献：
  名称：

  Non-CRET-Based Green Chemiluminescence of Imidazopyrazinone Modified by 2,3,6,7-Tetrahydro-1H,5H-benzo[i,j]quinolizine as a Strong Electron-Donating Unit

  摘要：

  A new imidazopyrazinone derivative, 1, having a 2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl (julolidin-9-yl) group at the 6-position, was synthesized and exhibited a largely red-shifted chemiluminescence in diglyme containing acetate buffer caused by a strong electron donation from the julolidin-9-yl group. The maximum wavelength was observed at 523 nm, which represents the most red-shifted light achieved only by the electron-donating effect from the 6-position of the imidazopyrazinone skeleton without any aids of extended at-conjugation systems or longer-wavelength-light emitting fluorophores.

  DOI：

  10.3987/com-10-12024

文献信息

• Non-CRET-Based Green Chemiluminescence of Imidazopyrazinone Modified by 2,3,6,7-Tetrahydro-1H,5H-benzo[i,j]quinolizine as a Strong Electron-Donating Unit
  作者：Ryota Saito

  DOI：10.3987/com-10-12024

  日期：——

  A new imidazopyrazinone derivative, 1, having a 2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl (julolidin-9-yl) group at the 6-position, was synthesized and exhibited a largely red-shifted chemiluminescence in diglyme containing acetate buffer caused by a strong electron donation from the julolidin-9-yl group. The maximum wavelength was observed at 523 nm, which represents the most red-shifted light achieved only by the electron-donating effect from the 6-position of the imidazopyrazinone skeleton without any aids of extended at-conjugation systems or longer-wavelength-light emitting fluorophores.