1,3-diphenyl-3-(dodecylsulfanyl)propan-1-one | 98665-61-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 1,3-diphenyl-3-(dodecylsulfanyl)propan-1-one
• 英文别名: 3-dodecylmercapto-1,3-diphenyl-propan-1-one；3-Dodecylmercapto-1,3-diphenyl-propan-1-on；3-Dodecylsulfanyl-1,3-diphenyl-propan-1-one；3-dodecylsulfanyl-1,3-diphenylpropan-1-one
• CAS: 98665-61-3
• 化学式: C₂₇H₃₈OS
• 分子量: 410.664
• InChiKey: PURSLCMNDAPDNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  29
• 可旋转键数：
  16
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯甲醛 在 KF/Al2O3 50% 作用下， 以 甘油 为溶剂， 反应 7.0h， 生成 1,3-diphenyl-3-(dodecylsulfanyl)propan-1-one
  参考文献：
  名称：

  Synthesis of β-Aryl-β-sulfanyl Ketones by a Sequential One-Pot Reaction Using KF/Al₂O₃ in Glycerol

  摘要：

  The title compounds were synthesized by a sequential one-pot reaction of aryl aldehydes, aryl-methyl ketones, and thiols promoted by KF/Al2O3. This methodology affords a large number of -aryl--sulfanyl ketone derivatives from aliphatic and aromatic thiols in good yields and is also applicable for solid substrates. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2013.788720

文献信息

• Aroyl disulfides as promoter-modifiers for copolymerization of butadiene and styrene
  作者：Robert L. Frank、James R. Blegen、Archie Deutschman

  DOI：10.1002/pol.1948.120030108

  日期：1948.2

  veratroyl, p-bromobenzoyl, p-phenylbenzoyl, p-benzoylbenzoyl, p-methylsulfonylbenzoyl, p(N,N-dimethylsulfonamido)-benzoyl and -naphthoyl disulfides are promoters of the emulsion copolymerization of butadiene and styrene, but exhibit little effect on the polymer properties. Furoyl, phenyl, p-chlorophenyl and p-bromophenyl disulfides are neither promoters nor modifiers.

  苯甲酰基、茴香酰基、藜芦酰基、对溴苯甲酰基、对苯基苯甲酰基、对苯甲酰基苯甲酰基、对甲磺酰基苯甲酰基、对(N,N-二甲基磺酰氨基)-苯甲酰基和-萘甲酰基二硫化物是丁二烯和苯乙烯乳液共聚的促进剂，但表现出很小对聚合物性能的影响。呋喃酰基、苯基、对氯苯基和对溴苯基二硫化物既不是促进剂也不是改性剂。
• β-Ketosulfides
  作者：Frank. Kipnis、John. Ornfelt

  DOI：10.1021/ja01178a518

  日期：1949.10
• Synthesis of <font>β</font>-Aryl-<font>β</font>-sulfanyl Ketones by a Sequential One-Pot Reaction Using KF/Al₂O₃ in Glycerol
  作者：Gelson Perin、Katiúcia Mesquita、Tainara P. Calheiro、Márcio S. Silva、Eder J. Lenardão、Diego Alves、Raquel G. Jacob

  DOI：10.1080/00397911.2013.788720

  日期：2014.1.2

  The title compounds were synthesized by a sequential one-pot reaction of aryl aldehydes, aryl-methyl ketones, and thiols promoted by KF/Al2O3. This methodology affords a large number of -aryl--sulfanyl ketone derivatives from aliphatic and aromatic thiols in good yields and is also applicable for solid substrates. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]