1,6-bis(pyridine-4-yloxy)-hexane | 726697-45-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,6-bis(pyridine-4-yloxy)-hexane
• 英文别名: 1,6-di-(4-pyridyloxy)hexane；4-(6-Pyridin-4-yloxyhexoxy)pyridine
• CAS: 726697-45-6
• 化学式: C₁₆H₂₀N₂O₂
• 分子量: 272.347
• InChiKey: DCSMWSSYGRIPBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  44.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,6-bis(pyridine-4-yloxy)-hexane 、 2-溴甲基萘 以 乙腈 为溶剂， 反应 12.0h， 以90%的产率得到
  参考文献：
  名称：

  Cucurbit[8]uril-based supramolecular polymers: promoting supramolecular polymerization by metal-coordination

  摘要：

  通过采用瓜环[8]脲基主客体相互作用作为驱动力，在线 性超分子聚合物的得到了在水溶液中的获得.的可溶于水的单体通过直接金属配位准备.刚性的和大的三联吡啶–Fe连接剂可以有效地提高单体的溶解度并抑制其环化，从而促进超分子聚合。

  DOI：

  10.1039/c3cc41864b
• 作为产物：
  描述：

  1,6-己二醇 、 4-氯吡啶盐酸盐 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 mineral oil 为溶剂， 反应 49.0h， 以49%的产率得到1,6-bis(pyridine-4-yloxy)-hexane
  参考文献：
  名称：

  Hard Phase Crystallization Directs the Phase Segregation of Hydrogen-Bonded Supramolecular Polymers

  摘要：

  A growing body of work shows that the phase behavior of supramolecular polymers assembled from telechelic building blocks featuring binding motifs at the two termini is quite similar to that of conventional block copolymers. However, it remains unclear how crystallization of the phase formed by the binding motifs, which occurs in many supramolecular polymers, affects the phase morphology of such materials. Here we report a systematic investigation of a series of supramolecular polymers based on poly(ethylene-co-butylene) (PEB) telechelics and the complementary H-bonding pair isophthalic acid-pyridine (IPA-Py). These polymers were designed to feature two blocks that assemble into an amorphous low-glass-transition phase formed by the PEB segments and crystalline domains consisting of the binding motifs. The nature of the latter was systematically varied via the choice of the pyridine employed. The influence of the binding motif on the phase morphology and thereby properties of these supramolecular polymers was investigated by means of thermal analysis, polarized optical microscopy, (dynamic) mechanical analyses, small-angle X-ray scattering, and transmission electron microscopy. In the melted state, all materials assembled into hexagonal phases. However, when cooled below the crystallization temperature of the IPA-Py domains, three different scenarios were observed: breakout crystallization resulting in complex morphologies, retention of the melt morphology, and the formation of a lamellar phase.

  DOI：

  10.1021/acs.macromol.8b02502

文献信息

• Supramolecular liquid crystals displaying competitive hydrogen bonding: Mesogenic associative chain structures using rigid and flexible pyridyl groups
  作者：Eric A. John、Michael D. Heltne、Evan C. Bornowski、David J. Lindberg、Joshua D. Carli、Seth B. Legare、John T. Carli、Kurt N. Wiegel

  DOI：10.1080/15421406.2019.1685740

  日期：2019.9.22

  A series of liquid-crystalline supramolecular copolymers formed through hydrogen bonding has been created. These polymers are composed of a bis-benzoic acid and two different pyridyl species - a small rigid bispyridyl capable of forming a mesophase when assembled and one of a pair of flexible bis pyridyl non-mesogenic "disruptor" species. The latter set of molecules consist of the pyridyl functionality separated by six or ten methylene units (6BPD and 10BPD, respectively). It was found that the associative chain polymers display monotropic characteristics depending upon the length of the methylene spacer group. The hexamethylene chain produced smectic phases up to 15% composition and cleared nematic characteristics at 70% loading. The decamethylene species eliminated smectic phases at 5% loading and displayed nematic phases up to 40% inclusion. It is believed that the increased length and flexibility of the alkyl chain allows for too much conformational mobility and freedom to efficiently form liquid-crystalline phases at high concentrations.