7-Hydroxy-2-methyl-phenanthren | 111589-12-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 7-Hydroxy-2-methyl-phenanthren
• 英文别名: 7-Methyl-[2]phenanthrol；7-Methyl-phenanthren-2-ol；7-Methyl-2-phenanthrol；7-methylphenanthren-2-ol
• CAS: 111589-12-9
• 化学式: C₁₅H₁₂O
• 分子量: 208.26
• InChiKey: NXSDACJRKYMDLA-UHFFFAOYSA-N

物化性质

• 熔点：
  190-191 °C
• 沸点：
  416.4±14.0 °C(Predicted)
• 密度：
  1.208±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(3-甲氧基苯基)乙醇 在 碘 、 氧气 、 silver trifluoroacetate 、 三溴化硼 、 三苯基膦 、 nickel dichloride 、 锌 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 、 xylene 、 苯 为溶剂， 反应 20.0h， 生成 7-Hydroxy-2-methyl-phenanthren
  参考文献：
  名称：

  摘要：

  9,10-Dihydrophenanthrenes and phenanthrenes, mimics of natural compounds with strong antialgal activity, have been synthesized through cross-coupling of 1-(2-iodo-5-methoxy)-phenylethanol with variously substituted iodobenzenes. The synthetic compounds, bearing a hydroxyl or a methoxyl group at C-2 and a methyl in the C ring, were tested against the green alga Selenastrum capricornutum. All compounds, except 2-methoxy-7-methylphenanthrene, caused inhibition of algal growth by more than 70% at 10(-4) M, and many of them retained this strong activity at 10(-5) M.

  DOI：

  10.1023/a:1005463802388

文献信息

• PHOTOREACTIVE COMPOUNDS
  申请人：Lincker Frederic

  公开号：US20140192305A1

  公开（公告）日：2014-07-10

  The present invention relates to photoreactive compounds that are particularly useful in materials for the alignment of liquid crystals.

  本发明涉及光反应性化合物，特别适用于液晶对准材料的制作。
• Dane; Schmitt, Justus Liebigs Annalen der Chemie, 1938, vol. 536, p. 196,197,200
  作者：Dane、Schmitt

  DOI：——

  日期：——
• Condensation of 1-(2-a cetoxyvinyl)-3,4-dihydro-6 -methoxynaphthalene with citraconic anhydride and with 2, 5-dimethyl-p-benzoquinone
  作者：T. I. Sorkina、I. I. Zaretskaya、I. V. Torgov

  DOI：10.1007/bf00844488

  日期：1964.11
• US9366906B2
  申请人：——

  公开号：US9366906B2

  公开（公告）日：2016-06-14
• ——
  作者：M. Dellagreca、A. Fiorentino、P. Monaco、A. Pollio、L. Previtera、A. Zarrelli

  DOI：10.1023/a:1005463802388

  日期：——

  9,10-Dihydrophenanthrenes and phenanthrenes, mimics of natural compounds with strong antialgal activity, have been synthesized through cross-coupling of 1-(2-iodo-5-methoxy)-phenylethanol with variously substituted iodobenzenes. The synthetic compounds, bearing a hydroxyl or a methoxyl group at C-2 and a methyl in the C ring, were tested against the green alga Selenastrum capricornutum. All compounds, except 2-methoxy-7-methylphenanthrene, caused inhibition of algal growth by more than 70% at 10(-4) M, and many of them retained this strong activity at 10(-5) M.