threo-10,11-dimethyleicosane | 50687-89-3

• 分子结构分类: 有机化合物 - 碳氢化合物 - 饱和烃
• 英文名称: threo-10,11-dimethyleicosane
• 英文别名: (10R,11R)-10,11-dimethylicosane
• CAS: 50687-89-3；124052-63-7；137035-74-6
• 化学式: C₂₂H₄₆
• 分子量: 310.607
• InChiKey: FQUKLYIORXDPRI-FGZHOGPDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.54
• 重原子数：
  22.0
• 可旋转键数：
  17.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  1-十一烯 在 二氯二茂锆 、 (C₁₁H₂₃)3Al 、 oxonium 作用下， 生成 threo-10,11-dimethyleicosane
  参考文献：
  名称：

  新型有机铝化合物的取代基和立体选择性合成-取代的氧化铝环戊烷和氧化铝环戊烯

  摘要：

  A novel regio- and stereoselective method has been developed for the catalytic cyclometallation of olefins and acetylenes with alkylalanes in the presence of Cp(2)ZrCl(2), to give in one stage high yields of 3-substituted aluminacyclopentanes and aluminacyclopentenes. Applications of these reactions to a wide range of linear and cyclic olefins and to those containing functional substituents have been studied. The transformation of the aluminacyclopentanes thus produced, into five-membered heterocycles, mono- and di-substituted cyclobutanes and cyclopropanes, has been demonstrated.

  DOI：

  10.1016/0022-328x(94)88022-0

文献信息

• Synthesis and conversions of metallocycles. 7. A novel approach to the synthesis of 3,4-dialkyl-substituted aluminacyclopentanes in the presence of Cp2ZrCl2
  作者：U. M. Dzhemilev、A. G. Ibragimov、A. B. Morozov、R. R. Muslukhov、G. A. Tolstikov

  DOI：10.1007/bf00961245

  日期：1991.7

  A novel approach was developed for the stereoselective synthesis of trans-3,4-dialkyl-substituted aluminacyclopentanes from alpha-olefins, metallic magnesium, and EtAlCl2 in the presence of catalytic amounts of CP2ZrCl2. The hydrolysis and deuterolysis products of the 3,4-dialkyl-substituted aluminacyclopentanes obtained are only in the trans configuration.