7-dimethylamino-4-hydroxy-1-methyl-1H-quinolin-2-one | 31136-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-dimethylamino-4-hydroxy-1-methyl-1H-quinolin-2-one
• 英文别名: 7-Dimethylamino-4-hydroxy-1-methyl-chinolin-(2)；7-(dimethylamino)-4-hydroxy-1-methylquinolin-2(1H)-one；7-(dimethylamino)-4-hydroxy-1-methylquinolin-2-one
• CAS: 31136-95-5
• 化学式: C₁₂H₁₄N₂O₂
• 分子量: 218.255
• InChiKey: HIKUCHLSTUZMDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  7-dimethylamino-4-hydroxy-1-methyl-1H-quinolin-2-one 在 三氟化硼乙醚 、 乙酸酐 、 乙二醇 、 sodium hydroxide 作用下， 以 水 、 乙腈 为溶剂， 反应 14.0h， 生成 2,2-difluoro-4,6-dimethyl-5-oxo-(5H)-8-dimethylaminoquinolino[4,3-d]-1,3,2-(2H)-dioxaborine
  参考文献：
  名称：

  The structural criteria of hydrolytic stability in series of dioxaborine polymethine dyes

  摘要：

  The structural criteria that affect stability to the alkaline hydrolysis of dioxaborine dyes were analyzed Dyes with different electron-donor and electron-withdrawing groups conjugated with dioxaborine cycle and also having some stem effects were analyzed For this purpose some new dioxaborine dyes were synthesized It was shown that electron-donor substituents unlike electron-withdrawing ones increase the hydrolytic stability of the dioxaborine dyes The possible way of the basic hydrolysis of dioxaborine dyes was suggested The products of the partial hydrolysis of the symmetrical dioxaborine dyes were first obtained (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.dyepig.2010.09.007

文献信息

• Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses
  申请人：L'OREAL

  公开号：US20040231067A1

  公开（公告）日：2004-11-25

  The subject of the present application is a dyeing composition for dyeing keratinous fibres, in particular human keratinous fibres such as hair, comprising, in an appropriate dyeing medium, at least one cationic tertiary para-phenylenediamine containing a pyrrolidine ring, and at least one particular heterocyclic coupler. The subject of the invention is also the dyeing method using this composition.

  本申请的主题是一种染色组合物，用于染色角蛋白纤维，特别是人类角蛋白纤维，如头发，包括在适当的染料介质中，至少包含一种含有吡咯烷环的阳离子第三对苯二胺，以及至少一种特定的杂环偶合剂。本发明的主题还包括使用该组合物的染色方法。
• Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same
  申请人：COMBE INCORPORATED

  公开号：EP0593038A1

  公开（公告）日：1994-04-20

  A dyestuff composition for gradually dyeing hair by atmospheric oxidation wherein the dyestuff composition contains a dye component which becomes entrapped in hair fibers when the dyestuff composition is removed from the hair and which results in the gradual development of color in the hair due to atmospheric oxidation of the entrapped dye component. Also provided is a process of employing the dyestuff composition of this invention to gradually dye hair, the dyestuff composition being removed from the hair approximately 5 minutes after its application.

  一种用于通过大气氧化逐渐染发的染料组合物，其中染料组合物含有一种染料成分，当染料组合物从头发上去除时，该染料成分会被夹杂在头发纤维中，由于被夹杂的染料成分被大气氧化，导致头发逐渐显色。本发明还提供了一种使用本发明染料组合物逐渐染发的工艺，在使用本发明染料组合物约 5 分钟后，将其从头发上去除。
• Hair treatment composition
  申请人：Kao Corporation

  公开号：EP0890355A1

  公开（公告）日：1999-01-13

  The invention relates to a hair treatment composition comprising (a) a guanidium salt, (b) an alkalizing agent other than the guanidium salt and (c) a silicone. The use of the hair treatment composition permits brightening the color tone of the hair or dyeing the hair in good shades from a bright shade to a deep shade. The composition scarcely damages the hair, gives off little irritating odor and has low irritativeness to the scalp.

  本发明涉及一种头发处理组合物，其中包括：(a) 胍盐；(b) 除胍盐以外的碱化剂；(c) 硅氧烷。使用这种头发处理组合物可以提亮头发的色调，或将头发染成从亮色到深色的良好色调。这种组合物对头发几乎没有损害，几乎不散发刺激性气味，对头皮的刺激性也很低。
• Dye composition for keratinous fibers comprising a polymeric thickener
  申请人：Kao Corporation

  公开号：EP1133974A2

  公开（公告）日：2001-09-19

  Provided is a dye composition for keratinous fibers, which comprises (A) a hydrolyzate of a lower alkyl vinyl ether/maleic anhydride copolymer partially crosslinked with a terminal unsaturated diene compound, or a monoalkyl ester of the hydrolyzate; and (B) a dye. The dye composition for keratinous fibers according to the present invention has a stable and appropriate viscosity even in a wide pH range and even in a system containing a salt or solvent at a high concentration; and has excellent usability and dyeing properties. It is particularly suited for use with an acid dye.

  本发明提供了一种用于角质纤维的染料组合物，它包括 (A) 部分与末端不饱和二烯化合物交联的低级烷基乙烯基醚/马来酸酐共聚物的水解物，或水解物的单烷基酯；以及 (B) 染料。 根据本发明的用于角质纤维的染料组合物，即使在较宽的 pH 值范围内，甚至在含有高浓度盐或溶剂的体系中，也具有稳定和适当的粘度；并且具有优异的使用性能和染色性能。 它特别适合与酸性染料一起使用。
• Hair dyeing process
  申请人：Kao Corporation

  公开号：EP1325733A2

  公开（公告）日：2003-07-09

  Hair can be dyed by applying an oxidizing-agent-free, air-oxidative, one-pack hair dye composition to the hair without mixing the hair dye composition with an oxidizing agent and, after the hair is left over for 5 minutes to 1 hour, rinsing off the hair dye composition with water. The hair dye composition comprises: (a) a water soluble salt of a transition metal: 0.001 to 10 wt.% in terms of an anhydride based on the whole composition, (b) a chelating agent capable of coordinating on said transition metal: 0.001 to 10 wt.% based the whole composition, and (c) a color-developing substance: 0.001 to 10 wt.% based on the whole composition. According to the present invention, hair can be dyed by a convenient procedure without damage. The present invention is also excellent in dyeing properties and color variations.

  在头发上涂抹不含氧化剂的空气氧化型单组分染发剂组合物，而不将染发剂组合物与氧化剂混合，在头发上停留 5 分钟至 1 小时后，用水冲洗掉染发剂组合物，即可染发。染发组合物包括 (a) 一种过渡金属的水溶性盐：以酸酐计，占整个组合物的 0.001 至 10 wt.%、 (b) 能够与所述过渡金属配位的螯合剂：以整个组合物计，占 0.001 至 10 wt.%；以及 (c) 一种显色物质：(c) 显色物质：占整个组合物的 0.001 至 10 wt.%。 根据本发明，可以通过简便的程序染发而不会对头发造成损伤。本发明在染色性能和颜色变化方面也非常出色。