2-乙基-3-甲基丁-2-烯酸 | 60582-21-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-乙基-3-甲基丁-2-烯酸
• 英文名称: 2-Ethyl-3-methyl-2-butenoic acid
• 英文别名: 2-Ethyl-3-methylbut-2-enoic acid
• CAS: 60582-21-0
• 化学式: C₇H₁₂O₂
• mdl: MFCD19228500
• 分子量: 128.171
• InChiKey: SUAWXOQFWMLUMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-乙基-3-甲基丁-2-烯酸 在 dirhodium tetraacetate 草酰氯 、 三乙胺 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 反应 4.0h， 生成 2-Ethyl-3-methyl-cyclopent-2-en-1-on
  参考文献：
  名称：

  Regioselectivity of rhodium(II)-catalyzed decomposition of 1-alkyl-1-(diazoacetyl)alkenes. Synthesis of 2-alkyl-2-cyclopentenones and 2-alkylidenecyclopentanones

  摘要：

  The synthesis of 1-alkyl-1-(diazoacetyl)alkenes and their dirhodium tetraacetate catalyzed transformation into 2-cyclopentenones and 2-alkylidenecyclopentanones are described. The competitive, intramolecular carbon-hydrogen insertion at two gamma-centers is discussed.

  DOI：

  10.1021/jo00025a022
• 作为产物：
  描述：

  3,3-二甲基丙烯酸甲酯 在 碘代三甲硅烷 、 氢溴酸 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 lithium diisopropyl amide 作用下， 以 四氯化碳 、 氯仿 、 苯 为溶剂， 反应 47.0h， 生成 2-乙基-3-甲基丁-2-烯酸
  参考文献：
  名称：

  Regioselectivity of rhodium(II)-catalyzed decomposition of 1-alkyl-1-(diazoacetyl)alkenes. Synthesis of 2-alkyl-2-cyclopentenones and 2-alkylidenecyclopentanones

  摘要：

  The synthesis of 1-alkyl-1-(diazoacetyl)alkenes and their dirhodium tetraacetate catalyzed transformation into 2-cyclopentenones and 2-alkylidenecyclopentanones are described. The competitive, intramolecular carbon-hydrogen insertion at two gamma-centers is discussed.

  DOI：

  10.1021/jo00025a022

文献信息

• STABILIZATION OF ACTIVE METAL CATALYSTS AT METAL-ORGANIC FRAMEWORK NODES FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS
  申请人：The University of Chicago

  公开号：US20180361370A1

  公开（公告）日：2018-12-20

  Metal-organic framework (MOFs) compositions based on post¬synthetic metalation of secondary building unit (SBU) terminal or bridging OH or OH 2 groups with metal precursors or other post-synthetic manipulations are described. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations, including the regioselective boryiation and siiylation of benzyiic C—H bonds, the hydrogenation of aikenes, imines, carbonyls, nitroarenes, and heterocycles, hydroboration, hydrophosphination, and cyclization reactions. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.

  基于后合成金属化的次级构建单元（SBU）端部或桥接的OH或OH2基团与金属前体或其他后合成操作的金属有机框架（MOFs）组成物被描述。这些MOFs提供了一系列多功能的可回收和可重复使用的单位固体催化剂，用于催化各种不对称有机转化，包括对苯基C—H键的区域选择性硼化和硅基化，烯烃、亚胺、醛酮、硝基芳烃和杂环化合物的加氢，氢硼化，氢磷化和环化反应。这些固体催化剂也可以集成到流动反应器或超临界流体反应器中。
• Method for producing anellated tetrahydro-{1h}-triazoles
  申请人：——

  公开号：US20040097728A1

  公开（公告）日：2004-05-20

  The present invention relates to a process for preparing fused tetrahydro-[ 1 H]-triazoles of the formula I 1 where the variables R a , Z, Z 1 , X, W, n and Q are as defined in claim 1, by cyclization of compounds of the formula II 2 where R is C(X)OR 2 or C(X)SR 2 , where X is oxygen or sulfur, and R 2 is as defined in claim 1, in the presence of a base. The invention also relates to compounds of the formula I where W is sulfur if Z is a methylene group optionally substituted by R a , and furthermore to compounds of the formula I where Q is a benzoxazole or benzothiazole radical, and to the use of these compounds as herbicides.

  本发明涉及一种制备公式I的熔融四氢咪唑的方法，其中变量Ra、Z、Z1、X、W、n和Q如权利要求1中定义，通过在碱存在下，将公式II的化合物环化得到，其中R为C(X)OR2或C(X)SR2，其中X为氧或硫，R2如权利要求1中定义。该发明还涉及公式I的化合物，其中如果Z是可选地由Ra取代的亚甲基基团，则W为硫，此外还涉及公式I的化合物，其中Q为苯并噁唑或苯并噻唑基团，并将这些化合物用作除草剂。
• Acid-Catalyzed Rearrangements of Vinylketene/Cyclopentadiene Adducts
  作者：Rima Huston、Max Rey、Andr� S. Drieding

  DOI：10.1002/hlca.19820650530

  日期：1982.7.28

  Säurekatalysierte Umlagerungen von Vinylketen/Cyciopentadien-Addukten

  SäurekatalysierteUmlagerungen von Vinylketen / Cyciopentadien-Addukten
• METHOD FOR PREPARING MICROCAPSULES BY DOUBLE EMULSION
  申请人：Calyxia

  公开号：EP3144058A1

  公开（公告）日：2017-03-22

  The present invention relates to a method for preparing solid microcapsules (20), comprising the steps of: a) adding under agitation a composition C1 comprising at least one active material to a cross-linkable liquid composition C2, wherein the active material is not an additive to be used in the lubricant, fuel or bitumen industries, or in drilling sludges or muds, or an additive to be used in oil exploration/production, composition C1 and composition C2 being immiscible with each other, so that a first emulsion is obtained, said first emulsion comprising droplets (1) of composition C1 dispersed in composition C2, b) adding under agitation the first emulsion obtained in step a) to a liquid composition C3, composition C3 and composition C2 being immiscible with each other, so that a second emulsion is obtained, said second emulsion comprising droplets (5) dispersed in composition C3, c) loading the second emulsion obtained in step b) in a mixer which applies a homogeneous controlled shear rate to said second emulsion, said shear rate being from 1 000 s-1 to 100 000 s-1, so that a third emulsion is obtained, said third emulsion comprising droplets (10) dispersed in composition C3, and d) cross-linking the droplets (10) obtained in step c), so that solid microcapsules (20) dispersed in composition C3 are obtained.

  本发明涉及一种制备固体微胶囊（20）的方法，包括以下步骤： a) 在搅拌下将包含至少一种活性材料的组合物 C1 加入到可交联的液体组合物 C2 中、 其中，活性材料不是用于润滑剂、燃料或沥青工业、钻井泥浆或泥浆中的添加剂，也不是用于石油勘探/生产中的添加剂、 组合物 C1 和组合物 C2 互不相溶、 从而得到第一乳液，所述第一乳液包括分散在成分 C2 中的成分 C1 液滴 (1)、 b) 在搅拌下将步骤 a) 中得到的第一乳液加入液体组合物 C3 中、 组合物 C3 和组合物 C2 互不相溶、 从而得到第二乳液，所述第二乳液包括分散在成分 C3 中的液滴 (5)、 c) 将步骤 b) 中得到的第二乳液装入混合器中，该混合器对第二乳液施加均匀可控的剪切速率，所述剪切速率为 1 000 s-1 至 100 000 s-1、 从而得到第三乳液，所述第三乳液包括分散在组合物 C3 中的液滴（10），以及 d) 交联步骤 c) 中得到的液滴（10）、 从而得到分散在组合物 C3 中的固体微胶囊（20）。
• Method for preparing microcapsules by double emulsion
  申请人：CALYXIA

  公开号：US10807060B2

  公开（公告）日：2020-10-20

  A method for preparing solid microcapsules, comprising the steps of adding under agitation a composition C1 comprising at least one active material to a cross-linkable liquid composition C2, the active material is not an additive to be used in the lubricant, fuel or bitumen industries, drilling sludges or muds, or oil exploration/production, compositions C1 and C2 being immiscible with each other. A first emulsion is obtained comprising droplets of composition C1 dispersed in composition C2, adding under agitation the first emulsion to a liquid composition C3, composition C3 and composition C2 being immiscible with each other, to obtain a second emulsion comprising droplets dispersed in composition C3. Loading the second emulsion in a mixer which applies a homogeneous controlled shear rate to said second emulsion, said shear rate being from 1 000 s-1 to 100 000 s-1, to obtain a third emulsion comprising droplets dispersed in composition C3, and cross-linking the droplets so that solid microcapsules dispersed in composition C3 are obtained.

  一种制备固体微胶囊的方法，包括以下步骤：在搅拌下将包含至少一种活性材料的组合物 C1 加入可交联的液体组合物 C2 中，活性材料不是用于润滑剂、燃料或沥青工业、钻井泥浆或泥浆或石油勘探/生产的添加剂，组合物 C1 和 C2 彼此不相溶。在搅拌下将第一乳液加入液体成分 C3（成分 C3 和成分 C2 互不相溶），得到由分散在成分 C3 中的液滴组成的第二乳液。将第二乳液装入混合器中，该混合器对所述第二乳液施加均匀可控的剪切速率，所述剪切速率为 1 000 s-1 至 100 000 s-1，以获得包含分散在组合物 C3 中的液滴的第三乳液，并使液滴交联，从而获得分散在组合物 C3 中的固体微胶囊。