(E)-ethyl 3-(4-(perfluorooctyl)phenyl)but-2-enoate | 1343512-42-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-ethyl 3-(4-(perfluorooctyl)phenyl)but-2-enoate
• 英文别名: ethyl (E)-3-[4-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)phenyl]but-2-enoate
• CAS: 1343512-42-4
• 化学式: C₂₀H₁₃F₁₇O₂
• 分子量: 608.295
• InChiKey: MUDQHIVFDFBOGB-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  39
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  19

反应信息

• 作为产物：
  描述：

  4-(perfluorooctyl)benzenediazonium trifluoroacetate 、 反式-2-丁烯酸乙酯 在 di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium(II) dimer 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以35%的产率得到(E)-ethyl 3-(4-(perfluorooctyl)phenyl)but-2-enoate
  参考文献：
  名称：

  Fluorous aryl compounds by Matsuda–Heck reaction

  摘要：

  Fluorous aryl compounds are obtained through the arylation of different electron-rich and electron-poor olefins with an arenediazonium salt bearing a fully fluorinated octyl-ponytail at the para position. The Matsuda-Heck reactions are catalyzed by Pd(OAc)(2) or 4-hydroxyacetophenone oxime-derived palladacycle as efficient sources of Pd nanoparticles, with loadings of 1 mol % Pd, at room temperature, in methanol and without the need to add external base. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.09.046

文献信息

• Fluorous aryl compounds by Matsuda–Heck reaction
  作者：Jordi Salabert、Rosa María Sebastián、Adelina Vallribera、Anna Roglans、Carmen Nájera

  DOI：10.1016/j.tet.2011.09.046

  日期：2011.11

  Fluorous aryl compounds are obtained through the arylation of different electron-rich and electron-poor olefins with an arenediazonium salt bearing a fully fluorinated octyl-ponytail at the para position. The Matsuda-Heck reactions are catalyzed by Pd(OAc)(2) or 4-hydroxyacetophenone oxime-derived palladacycle as efficient sources of Pd nanoparticles, with loadings of 1 mol % Pd, at room temperature, in methanol and without the need to add external base. (C) 2011 Elsevier Ltd. All rights reserved.