2-乙氧基-6-甲基吡嗪 | 53163-97-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-乙氧基-6-甲基吡嗪
• 英文名称: 2-Ethoxy-6-methylpyrazine
• CAS: 53163-97-6
• 化学式: C₇H₁₀N₂O
• mdl: MFCD07787591
• 分子量: 138.17
• InChiKey: XBLZVFYOCZVABA-UHFFFAOYSA-N

物化性质

• LogP：
  1.74
• 保留指数：
  1048

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.428
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

文献信息

• Prevention of Illicit Manufacutre of Methamphetamine from Pseudoephedrine Using Food Flavor Excipients
  申请人：Satara Pharmaceuticals, LLC

  公开号：US20160089439A1

  公开（公告）日：2016-03-31

  The invention relates generally to ephedrine or pseudoephedrine compositions containing biocompatible organoleptic (food flavoring) excipients that would prevent the illicit manufacture of methamphetamine from ephedrine or pseudoephedrine.

  该发明通常涉及含有生物相容性感官（食品调味）赋形剂的麻黄碱或伪麻黄碱组合物，可防止从麻黄碱或伪麻黄碱制备冰毒。
• [EN] PREVENTION OF ILLICIT METHAMPHETAMINE MANUFACTURE FROM PSEUDOEPHEDRINE USING FOOD FLAVOR EXCIPIENTS<br/>[FR] PRÉVENTION DE LA FABRICATION ILLICITE DE MÉTHAMPHÉTAMINE À PARTIR DE PSEUDOÉPHÉDRINE À L'AIDE D'ARÔMES ALIMENTAIRES
  申请人：DAYA DRUG DISCOVERIES INC

  公开号：WO2015048597A1

  公开（公告）日：2015-04-02

  The invention relates generally to ephedrine or pseudoephedrine compositions containing biocompatible organoleptic excipients that would prevent the illicit manufacture of methamphetamine from ephedrine or pseudoephedrine. The organoleptic agents, typically used as food flavorings, are pyrazine based excipients, that when co-formulated with ephedrine or pseudoephedrine, prevent the isolation and converasion of pure methamphetamine.

  该发明通常涉及含有生物相容性感官助剂的麻黄碱或伪麻黄碱组合物，这些感官助剂可以防止从麻黄碱或伪麻黄碱制备冰毒。这些感官助剂通常用作食品香料，是基于吡嗪的助剂，与麻黄碱或伪麻黄碱共同配制时，可以防止纯冰毒的分离和转化。
• [EN] CTPS1 INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS DE CTPS1 ET LEURS UTILISATIONS
  申请人：NIMBUS CLOTHO INC

  公开号：WO2022087634A1

  公开（公告）日：2022-04-28

  The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CPTS1, and the treatment of CPTS1-mediated disorders.

  本发明提供了化合物、其组合物以及使用它们抑制CPTS1和治疗CPTS1介导的疾病的方法。
• HSP90 INHIBITORS
  申请人：Chen Young K.

  公开号：US20090305998A1

  公开（公告）日：2009-12-10

  The invention relates to HSP90 inhibiting compounds consisting of the formula: wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

  本发明涉及抑制HSP90的化合物，其由下式表示：其中变量如定义所述。本发明还涉及包括此类化合物的制药组合物、工具箱和制造物品；用于制备该化合物的方法和中间体；以及使用该化合物的方法。
• SOLID COMPOSITION COMPRISING IODINE AGENT AND SODIUM CHLORIDE HAVING IMPROVED WATER SOLUBILITY, AND ANTIVIRAL AND ANTIMICROBIAL COMPOSITION FOR EYE, ORAL CAVITY, NASAL CAVITY OR INHALATION CONTAINING AQUEOUS SOLUTION THEREOF
  申请人：Fluchem Ltd

  公开号：EP3650012A1

  公开（公告）日：2020-05-13

  The present invention relates to a solid composition comprising an iodine agent and sodium chloride having improved water solubility and to an antiviral and antimicrobial composition for an eye, oral cavity, nasal cavity or inhalation containing an aqueous solution thereof, wherein the solid composition comprises an iodine agent and sodium chloride or a mixture of an iodine agent, sodium chloride and a flavoring agent and is excellent in not only storage stability but also water solubility as a dissolution rate thereof for water is 30 seconds or less. In addition, the aqueous solution in which the solid composition is dissolved in water has an excellent effect of shielding from the unpleasant or irritating odor and taste of an iodine agent while also not causing pain or irritation, has an outstanding effect of preventing or treating infectious respiratory diseases such as a cold or influenza, and is applicable to all parts of a respiratory organ, such that the solution can be usefully used for the prevention or treatment of respiratory infectious diseases.

  本发明涉及一种由碘剂和氯化钠组成的固体组合物，该组合物具有更好的水溶性，还涉及一种用于眼部、口腔、鼻腔或吸入的含有其水溶液的抗病毒和抗菌组合物，其中固体组合物由碘剂和氯化钠或碘剂、氯化钠和调味剂的混合物组成，不仅具有出色的贮存稳定性，还具有出色的水溶性，因为其在水中的溶解速率为 30 秒或更短。此外，将固体组合物溶解于水的水溶液具有极佳的效果，既能屏蔽碘剂的难闻或刺激性气味和味道，又不会引起疼痛或刺激，在预防或治疗感冒或流感等呼吸道传染病方面效果显著，而且适用于呼吸器官的所有部位，因此该溶液可有效地用于预防或治疗呼吸道传染病。