cyclopropane-1r,2,3t-tricarboxylic acid | 877469-10-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: cyclopropane-1r,2,3t-tricarboxylic acid
• 英文别名: Cyclopropan-1r,2,3t-tricarbonsaeure；trans-Cyclopropan-tricarbonsaeure-(1.2.3)；trans-Cyclopropan-1,2,3-tricarbonsaeure；Cyclopropan-1,2,3-tricarbonsaeure；cyclopropane-1,2,3-tricarboxylic acid
• CAS: 877469-10-8
• 化学式: C₆H₆O₆
• mdl: MFCD00180923
• 分子量: 174.11
• InChiKey: UVIRSBTTXOHPDA-UHFFFAOYSA-N

物化性质

• 沸点：
  342.9±42.0 °C(Predicted)
• 密度：
  1.934±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  cyclopropane-1r,2,3t-tricarboxylic acid 在 乙酸酐 、 溶剂黄146 作用下， 生成 环丙烷-1,2,3-三羧酸酐
  参考文献：
  名称：

  Process for producing an intermediate of a new quinolone compound

  摘要：

  提供了一种高效的生产过程，适用于合成新的喹诺酮类抗真菌剂CP-99219的合成中间体。该生产过程的中间体由公式（IV）表示，其中R.sup.3表示苄基、二苯甲基等，R.sup.4表示1至8C的线性或支链烷基、环烷基等，该过程采用环丙烷三羧酸三酯作为起始物质，该三酯由公式（I）表示，其中R.sup.1和R.sup.2表示线性或支链烷基、环烷基、芳基或芳基烷基，并经过七个步骤。

  公开号：

  US05623078A1
• 作为产物：
  描述：

  Ethyl hexacyclopropan-carboxylat 在 barium dihydroxide 作用下， 生成 cyclopropane-1r,2,3t-tricarboxylic acid
  参考文献：
  名称：

  Koetz; Stahlmann, Journal fur praktische Chemie (Leipzig 1954), 1903, vol. <2>68, p. 163

  摘要：

  DOI：

文献信息

• Reactions of cycloalkanecarboxylic acids with SF4. I. Fluorination of cyclopropanepolycarboxylic acids with SF4
  作者：Yu.M. Pustovit、P.I. Ogojko、V.P. Nazaretian、L.B. Faryat'eva

  DOI：10.1016/0022-1139(93)02996-r

  日期：1994.12

  Cyclopropanecarboxylic acids possessing more than one carboxylic group readily undergo fluorination when treated with SF4 to yield the corresponding poly(trifluoromethyl)cyclopropanes and bicyclic ethers.

  当用SF 4处理时，具有一个以上羧基的环丙烷羧酸容易发生氟化反应，生成相应的聚（三氟甲基）环丙烷和双环醚。
• Process for producing an intermediate of a new quinolone compound
  申请人：Chisso Corporation

  公开号：US05623078A1

  公开（公告）日：1997-04-22

  A production process with good efficiency, and applicable to production of a synthetic intermediate of a new quinolone anti-fungus agent CP-99219, is provided. A production process of an intermediate of a new quinolone compound expressed by the formula (IV) ##STR1## wherein R.sup.3 represents a benzyl group, a diphenylmethyl group, etc. and R.sup.4 represents a linear or branched alkyl group of 1 to 8C, a cycloalkyl group, etc. which process employs as a starting substance, a cyclopropanetricarboxylic acid triester expressed by the formula (I) ##STR2## wherein R.sup.1 and R.sup.2 represent a linear or branched alkyl group, a cycloalkyl group, an aryl group or an aralkyl group, and passes through seven steps.

  提供一种高效的生产过程，适用于合成新的喹诺酮类抗真菌剂CP-99219的合成中间体。该生产过程是一种新的喹诺酮化合物的中间体的生产过程，该化合物由公式（IV）表示，其中R.sup.3代表苄基，二苯甲基等，R.sup.4代表1至8C的线性或支链烷基，环烷基等。该过程以环丙烷三羧酸三酯为起始物质，该三酯由公式（I）表示，其中R.sup.1和R.sup.2代表线性或支链烷基，环烷基，芳基或芳基烷基，并经过七个步骤。
• WATER-SOLUBLE FLAME-RETARDANT POLYESTER RESIN, RESIN COMPOSITION CONTAINING THE RESIN, AND FABRIC PRODUCT TREATED WITH THE RESIN COMPOSITION
  申请人：Goo Chemical Co., Ltd.

  公开号：EP1541611A1

  公开（公告）日：2005-06-15

  A water-soluble, flame retardant polyester resin is obtained by a condensation reaction or a polycondensation reaction of a dicarboxylic-acid component, a glycol component, a water-solubility imparting component and a reactive phosphorus-containing compound such that a ratio of the water-solubility imparting component in a total of the dicarboxylic-acid component and the water-solubility imparting component is in a range of 1 to 60 mol%. Since this polyester resin can be dissolved in a solvent by allowing a halogen-free, phosphorus-containing polyester with excellent flame resistance to have water solubility, it is possible to improve applicability and eliminate problems of working environment and environmental destruction resulting from organic solvents. In addition, even when treating substrates such as fibers and PET films with the polyester resin, there is no deterioration of these substrates.

  通过二羧酸组分、乙二醇组分、水溶性赋予组分和活性含磷化合物的缩合反应或缩聚反应，使水溶性赋予组分在二羧酸组分和水溶性赋予组分的总和中所占比例在 1 至 60 摩尔%的范围内，从而获得一种水溶性阻燃聚酯树脂。由于这种聚酯树脂可以溶解在溶剂中，使具有优异阻燃性的无卤含磷聚酯具有水溶性，因此可以提高适用性，消除有机溶剂造成的工作环境和环境破坏问题。此外，即使用聚酯树脂处理纤维和 PET 薄膜等基材，这些基材也不会变质。
• Hair cosmetic composition
  申请人：KAO CORPORATION

  公开号：EP1579842A2

  公开（公告）日：2005-09-28

  Provided is a hair cosmetic composition, which contains the following components (A) and (B): (A) a hydroxy-free tricarboxylic acid having from 4 to 20 carbon atoms in total, or salt thereof, and (B) at least one or more organic solvents selected from the group consisting of aromatic alcohols, N-alkylpyrrolidones, alkylene carbonates, polypropylene glycols, lactones and cyclic ketones, wherein the organic solvent has a ClogP of from -2 to 3; and wherein the hair cosmetic composition has a pH of from 2 to 5 at 25°C when diluted to 20 times the weight with water. Provided also is a hair quality improving method which comprises treating the hair with the hair cosmetic composition. The hair cosmetic composition of the present invention can for example give strength/body, manageability, and set retention property to the hair which is apt to be dry and moistureless owing to the damage by coloring, permanent waving, or repetition of excessive blow drying.

  本发明提供了一种头发化妆品组合物，它包含以下成分 (A) 和 (B)： (A) 总碳原子数为 4 至 20 的不含羟基的三羧酸或其盐，以及 (B) 至少一种或多种有机溶剂，这些有机溶剂选自由芳香醇、N-烷基吡咯烷酮、碳酸亚烷基酯、聚丙二醇、内酯和环酮组成的组，其中有机溶剂的 ClogP 值为-2 至 3；并且当用水稀释至 20 倍重量时，头发化妆品组合物在 25°C 时的 pH 值为 2 至 5。本发明还提供了一种改善发质的方法，该方法包括用头发化妆品组合物处理头发。 例如，本发明的头发化妆品组合物可以使由于染发、永久性烫发或反复过度吹干而容易干枯和失去水分的头发具有强韧/丰盈、易于打理和定型的特性。
• HEAT CARRIER COMPOSITION
  申请人：Shishiai-Kabushikigaisha

  公开号：EP1698678A1

  公开（公告）日：2006-09-06

  The present invention relates to a heat transfer medium composition which contains water, a glycol, alcohol and/or glycol ether as a main ingredient and a pH buffering agent. The composition provides improved and long lasting buffering in actual use to maintain the pH value of the medium within the appropriate range of pH 6 to pH 10. The pH buffering agent is prepared of an alicyclic compound where two members selected from among carboxyl and its salts are bonded to a ring-constituting carbon atom, or at least two members selected from the group are respectively bonded to as many neighboring carbon atoms. Alternatively, the pH buffering agent is prepared of a heterocyclic compound in which at least one ring-constituting carbon atom of the alicyclic compound is substituted by a nitrogen or oxygen atom, where two members selected from the group are bonded to a ring-constituting carbon atom, or at least two members selected from the group are respectively bonded to as many neighboring carbon atoms.

  本发明涉及一种导热介质组合物，其主要成分包括水、乙二醇、醇和/或乙二醇醚以及 pH 缓冲剂。在实际使用中，该组合物具有更好的持久缓冲作用，可将介质的 pH 值保持在 pH 6 至 pH 10 的适当范围内。pH 缓冲剂是由脂环族化合物制备的，其中从羧基及其盐类中选出的两个成员键合到一个构成环的碳原子上，或者从该基团中选出的至少两个成员分别键合到尽可能多的相邻碳原子上。或者，pH 缓冲剂由杂环化合物制备而成，其中脂环族化合物的至少一个构环碳原子被氮原子或氧原子取代，从该组中选出的两个成员与一个构环碳原子键合，或从该组中选出的至少两个成员分别与相邻的多个碳原子键合。