3,4-dimethyl-hex-1-yn-3-ol | 52187-77-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-dimethyl-hex-1-yn-3-ol
• 英文别名: 3,4-Dimethyl-hex-1-in-3-ol；Methyl-sek.-butyl-aethinyl-carbinol；3,4-Dimethylhex-1-yn-3-ol
• CAS: 52187-77-6
• 化学式: C₈H₁₄O
• 分子量: 126.199
• InChiKey: POXXEBWIHAYJMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,4-dimethyl-hex-1-yn-3-ol 在 mercury(II) sulfate 作用下， 生成 3-hydroxy-3,4-dimethyl-hexan-2-one
  参考文献：
  名称：

  Colonge, Bulletin de la Societe Chimique de France, 1931, vol. <4>49, p. 432

  摘要：

  DOI：
• 作为产物：
  描述：

  3-甲基-2-戊酮 在 sodium amide 作用下， 生成 3,4-dimethyl-hex-1-yn-3-ol
  参考文献：
  名称：

  Colonge, Bulletin de la Societe Chimique de France, 1931, vol. <4>49, p. 432

  摘要：

  DOI：

文献信息

• LiO^<i>t</i>Bu-Promoted <i>trans</i>-Stereoselective and β-Regioselective Hydroboration of Propargyl Alcohols
  作者：Xia Tian、Yu-Kun Zhang、Ya-Xin You、Jian-Rong Han、Qiu-Shi Cheng、Shi-Ming Fan、Di-Di Chen、Ting-Ting Wang、Shouxin Liu、Wei Su

  DOI：10.1021/acs.orglett.3c02411

  日期：2023.9.1

  (Bpin)2 as the boron reagent in dimethyl sulfoxide at room temperature. Both terminal and internal propargyl alcohols with diverse structures and functional groups underwent the transformation smoothly to produce β-Bpin-substituted (E)-allylic alcohols, of which the synthetic potentials were demonstrated by the downstream conversions of boronate, alkenyl, and hydroxyl groups.

  在室温下，仅以 LiOtBu 为碱，以 （Bpin）2 为硼试剂，即可在室温下在二甲基亚砜中实现方便高效的炔丙醇反式立体选择性和β区选择性硼氢化。具有不同结构和官能团的末端和内部炔丙醇都顺利地发生转化，生成 β-Bpin 取代 （E）-烯丙醇，其中合成潜力通过硼酸盐、烯基和羟基的下游转化得到证明。
• Room temperature stable, heat activated organopolysiloxane compositions
  申请人：Toray Silicone Company Limited

  公开号：EP0091291A2

  公开（公告）日：1983-10-12

  Organopolysiloxane compositions which react byway of a hydrosilylation reaction to undergo an increase in viscosity have improved resistance to reaction at room temperature (longer pot life) and/or an improved reaction rate at elevated temperature (shorter cure time) than analogous compositions of the art by incorporating therein an unsaturated hydrocarbon having from 6 to 10 carbon atoms, a terminal acetylenic linkage and an olefinic linkage conjugated therewith. The resulting compositions are useful for preparing various cured siloxanes such as resins, elastomers, gels and foams.

  通过氢硅烷化反应使粘度增加的有机聚硅氧烷组合物与本领域的类似组合物相比，在室温下具有更好的耐反应性（更长的固化寿命）和/或在高温下具有更好的反应速率（更短的固化时间），其方法是在组合物中加入具有 6 至 10 个碳原子的不饱和碳氢化合物、末端乙炔基连接和与之共轭的烯烃基连接。 由此产生的组合物可用于制备各种固化硅氧烷，如树脂、弹性体、凝胶和泡沫。
• Storage stable polyorganosiloxane compositions
  申请人：Toray Silicone Company Limited

  公开号：EP0117056A2

  公开（公告）日：1984-08-29

  The storage stability at ambient temperature of heat curable polyorganosiloxane compositions comprising a vinyl containing polyorganosiloxane, a polyorganosiloxane containing silicon-bonded hydrogen atoms and a platinum, palladium, or rhodium catalyst is improved using specified monohydrocarbyltrialkynyloxysilanes as storage stabilizers. The stabilizers do not interfere with curing of the compositions at elevated temperatures.

  使用特定的单羟基羰基三炔基氧基硅烷作为贮存稳定剂，可提高热固化聚有机硅氧烷组合物在环境温度下的贮存稳定性，该组合物由含乙烯基的聚有机硅氧烷、含硅键合氢原子的聚有机硅氧烷和铂、钯或铑催化剂组成。 稳定剂不会干扰组合物在高温下的固化。
• Heat-curable silicone compositions, use thereof and stabilizer therefor
  申请人：DOW CORNING CORPORATION

  公开号：EP0186439A2

  公开（公告）日：1986-07-02

  Organosilicon compositions which cure by way of a metal-catalyzed reaction of silicon-bonded hydroxyl radicals and/or silicon-bonded olefinic hydrocarbon radicals with silicon-bonded hydrogen atoms are stabilized for hours at room temperature by the incorporation of a hydrocarbonoxy-alkyl maleate. However, the stablized compositions are rapidly curable at low elevated temperature. Liquid organopolysiloxane compositions of this invention are particularly useful for coating operations, particularly paper coating operations to prepare an adhesive-releasing layer.

  通过金属催化硅键羟基自由基和/或硅键烯烃自由基与硅键氢原子发生反应而固化的有机硅组合物，可通过加入烃氧烷基马来酸盐在室温下稳定数小时。然而，稳定化后的组合物在低温升温条件下可快速固化。本发明的液态有机聚硅氧烷组合物特别适用于涂布作业，尤其是纸张涂布作业，以制备粘合剂释放层。
• Dental composition containing glass beads, process for production and use thereof
  申请人：3M Innovative Properties Company

  公开号：EP2044923A1

  公开（公告）日：2009-04-08

  The invention relates to a dental composition comprising a hardenable matrix and glass beads having a particle size (d50/µm) equal or below about 60 µm. The invention also relates to a method of producing this composition and its use.

  本发明涉及一种牙科组合物，包括可硬化基质和粒径（d50/µm）等于或小于约 60 µm 的玻璃珠。本发明还涉及生产这种组合物的方法及其用途。