2-bromo-9-(3-nitrophenyl)-9H-carbazole | 1313900-06-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-bromo-9-(3-nitrophenyl)-9H-carbazole
• 英文别名: 2-Bromo-9-(3-nitrophenyl)carbazole；2-bromo-9-(3-nitrophenyl)carbazole
• CAS: 1313900-06-9
• 化学式: C₁₈H₁₁BrN₂O₂
• 分子量: 367.202
• InChiKey: POOWLLGUJGPJBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  50.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-溴咔唑 、 1-碘-3-硝基苯 在 copper(l) iodide 、 caesium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 以85%的产率得到2-bromo-9-(3-nitrophenyl)-9H-carbazole
  参考文献：
  名称：

  N-Arylation of carbazole by microwave-assisted ligand-free catalytic CuI reaction

  摘要：

  N-Arylation of carbazole has been achieved in high yields within 1 h using a microwave-assisted catalytic CuI reaction with no organic ligand. The N-arylation can be performed by various arylhalides, such as phenyl, pyridine, thiophene, and thiazole moieties. Specifically, N-arylated bromocarbazoles were converted into useful synthetic intermediates for functionalized carbazole materials. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.05.022

文献信息

• N-Arylation of carbazole by microwave-assisted ligand-free catalytic CuI reaction
  作者：Jae Kwan Kwon、Joong Hyun Cho、Young-Sil Ryu、Se Hwan Oh、Eul Kgun Yum

  DOI：10.1016/j.tet.2011.05.022

  日期：2011.7

  N-Arylation of carbazole has been achieved in high yields within 1 h using a microwave-assisted catalytic CuI reaction with no organic ligand. The N-arylation can be performed by various arylhalides, such as phenyl, pyridine, thiophene, and thiazole moieties. Specifically, N-arylated bromocarbazoles were converted into useful synthetic intermediates for functionalized carbazole materials. (C) 2011 Elsevier Ltd. All rights reserved.