ethyl (2Z)-4-(2-furyl)-4-oxobut-2-enoate | 117937-17-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ethyl (2Z)-4-(2-furyl)-4-oxobut-2-enoate
• 英文别名: ethyl (Z)-4-(furan-2-yl)-4-oxobut-2-enoate
• CAS: 117937-17-4
• 化学式: C₁₀H₁₀O₄
• 分子量: 194.187
• InChiKey: AYGGXIICBGOISY-WAYWQWQTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  呋喃甲酰氯 、 ethyl (Z)-3-iodo-3-(trimethylsilyl)propenoate 在 neophyllithium 、 CuCN 作用下， 以 四氢呋喃 、 N-甲基吡咯烷酮 、 乙醚 为溶剂， 反应 1.0h， 以75%的产率得到ethyl (2Z)-4-(2-furyl)-4-oxobut-2-enoate
  参考文献：
  名称：

  Research on a compact adsorption room air conditioner

  摘要：

  A novel compact adsorption room air conditioner with a cooling capacity of 1 kW has been designed, and two prototypes have been built. A two bed, continuous adsorption refrigeration cycle with heat recovery and mass recovery is adopted. Micropore spherical silica gel and water are selected as the working pair. A gravity heat pipe with methanol as working medium is designed to output the cooling. Experimental investigations have indicated that under typical air conditioning conditions, for the first prototype, a cooling capacity of 687 W and a COP (coefficient of performance) of 0.307 can be obtained. However, for the improved one, a cooling capacity of 790 W and a COP of 0.446 can be reached. It is also proved that the operating temperatures have strong influences on the performance. The designed room air conditioner can be driven by a low grade heat source (< 90 degrees C) and has small dimensions of 300 mm (depth), 500 mm (width) and 950 mm (height). (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.enconman.2005.12.005

文献信息

• The reaction of alkyl 4-hydroxy-2-alkynoates and 4-hydroxy-2-alkyn-1-ones with palladium tributylammonium formate and with tributylamine: Preparation of 1,4-dicarbonyl compounds
  作者：A. Arcadi、S. Cacchi、F. Marinelli、D. Misiti

  DOI：10.1016/s0040-4039(00)80324-x

  日期：1988.1

  Ethyl 4-oxo-2-alkenoates and 1,4-dioxo-2-alkenes are easily prepared by treating ethyl 4-hydroxy-2-alkynoates and 4-hydroxy-2-alkyn-1-ones with n-tributylamine. Treatment of ethyl 4-hydroxy-2-alkynoates and 4-hydroxy-2-alkyn-1-ones with palladium-tributylammonium formate produces ethyl 4-oxo-alkanoates and 1,4-alkandiones in good to high yield through a novel one-pot isomerization/hydrogenation reaction

  通过用正三丁胺处理4-羟基-2-炔基乙酯和4-羟基-2-炔基-1-酮，可以容易地制备4-氧代-2-链烯酸乙酯和1，4-二氧代-2-链烯。用甲酸钯-三丁基铵处理4-羟基-2-链烷酸乙酯和4-羟基-2-炔基-1-酮可通过新颖的单-羟基苯甲酸乙酯生成4-氧代链烷酸乙酯和1,4-链烷酮，收率高至高。锅异构化/氢化反​​应。
• The in situ oxidation–Wittig reaction of α-hydroxyketones
  作者：Karen A. Runcie、Richard J. K. Taylor

  DOI：10.1039/b201513g

  日期：2002.4.19

  In situ oxidation–Wittig methodology has been applied to α-hydroxyketones avoiding the problems normally associated with α-ketoaldehydes; the procedure is practically simple, and in many cases gives high yields of the product γ-ketocrotonates; the procedure has also been successfully utilised with ethyl glycolate and glycolaldehyde dimer.

  原位氧化-维蒂希法已被应用于α-羟基酮，避免了通常与α-酮醛相关的问题；该程序非常简单，在许多情况下能够获得高产率的产物γ-酮基克酮酸酯；该程序还成功地应用于乙基甘醇酸盐和甘醛二聚体。
• ARCADI, A.;CACCHI, S.;MARINELLI, F.;MISITI, D., TETRAHEDRON LETT., 29,(1988) N 12, 1457-1460
  作者：ARCADI, A.、CACCHI, S.、MARINELLI, F.、MISITI, D.

  DOI：——

  日期：——