2-庚醇,2,5-二甲基- | 1561-18-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-庚醇,2,5-二甲基-
• 英文名称: 2,5-dimethylheptan-2-ol
• 英文别名: 2,5-dimethyl-2-heptan-1-ol；2-Heptanol, 2,5-dimethyl-
• CAS: 1561-18-8
• 化学式: C₉H₂₀O
• 分子量: 144.257
• InChiKey: LVIFBEPHIBJBEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  反式-2-甲基-4-己烯-2-醇 、 乙基溴化镁 在 titanium(IV) isopropylate 作用下， 以 乙醚 为溶剂， 反应 1.0h， 生成 2-庚醇,2,5-二甲基-
  参考文献：
  名称：

  Reductive ethylation of homoallyl alcohols with a disubstituted double bond with ethylmagnesium bromide in the presence of titanium(IV) isopropoxide

  摘要：

  Homoallyl and bishomoallyl alcohols with a disubstituted double bond treated with ethylmagnesium bromide in the presence of titanium(IV) isopropoxide are converted into the products of a reductive ethylation of the olefin fragment. Under similar conditions esters of beta,gamma-unsaturated carboxylic acids undergo a successive cyclopropanation of the ester group and reductive ethylation of the double carbon-carbon bond and yield 1-(3-ethylalkyl)cyclopropanols. The features of the observed reactions are explained in the framework of the carbometallation mechanism of the double carbon-carbon bond by the action of dialkoxytitanacyclopropane reagents.

  DOI：

  10.1134/s1070428006050034

文献信息

• Perfumed hypochlorite bleaching compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0622451B1

  公开（公告）日：1998-12-02
• ALKOXYLIERTE DUFTALKOHOLE UND IHRE VERWENDUNG
  申请人：Henkel Kommanditgesellschaft auf Aktien

  公开号：EP1268382A2

  公开（公告）日：2003-01-02
• INDOLE AND BENZOXAZINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
  申请人：Janssen Pharmaceuticals, Inc.

  公开号：EP2373649B1

  公开（公告）日：2013-01-23
• DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3
  申请人：Wisconsin Alumni Research Foundation

  公开号：EP2556054B1

  公开（公告）日：2017-09-27
• Process for hydrogenation of conjugated diene polymer
  申请人：——

  公开号：US20040082727A1

  公开（公告）日：2004-04-29

  A process for hydrogenation of a conjugated diene polymer. The conjugated diene polymer in an inert organic solvent is brought into contact with hydrogen in the presence of a hydrogenation catalyst composition to selectively hydrogenate the unsaturated double bonds in the conjugated diene units of the conjugated diene polymer. The hydrogenation catalyst composition includes: (I) a titanium compound; (II) a compound represented by formula (II): 1 wherein L is a Group IVB element, R is C 1 -C 12 alkyl or C 1 -C 12 cycloalkyl, X can be the same or different and is C 1 -C 12 alkyl, C 1 -C 12 alkoxy, C 1 -C 12 cycloalkoxy, halogen, or carbonyl; and (III) a trialkylaluminum compound.