2-Deoxy-DL-ribo-hexopyranose | 61-58-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Deoxy-DL-ribo-hexopyranose
• 英文别名: (4R,5R)-6-(hydroxymethyl)oxane-2,4,5-triol
• CAS: 61-58-5；13299-15-5；13299-16-6；14215-77-1；14215-78-2；20789-85-9；23568-30-1；25494-04-6；34339-39-4；34339-40-7；34339-46-3；34339-47-4；114717-20-3；114717-21-4；137491-75-9；137491-76-0
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: PMMURAAUARKVCB-YLZRJQLMSA-N

物化性质

• 熔点：
  175 °C
• 沸点：
  411.0±45.0 °C(Predicted)
• 密度：
  1.533±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.2
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS
  申请人：Ionis Pharmaceuticals, Inc.

  公开号：EP2992097B1

  公开（公告）日：2019-11-06
• Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives
  申请人：Tamerlani Giancarlo

  公开号：US20070083041A1

  公开（公告）日：2007-04-12

  Herein described is a process for the preparation of 1-chloro-3,5-di-O-acyl-2-de-oxy-L-ribofuranoside derivatives of general formula (I) useful as intermediates in processes for preparing nucleotides of the L series having antiviral activity.
• NEOGLYCORANDOMIZATION AND DIGITOXIN ANALOGS
  申请人：Langenhan Joseph M.

  公开号：US20090075842A1

  公开（公告）日：2009-03-19

  The present invention provides methods of producing libraries of compounds with enhanced desirable properties and diminished side effects as well as the compounds produced by the methods. In preferred embodiments, methods of the present invention use a universal chemical glycosylation method that employs reducing sugars and requires no protection or activation. In a preferred embodiment, the invention provides a library of neoglycoside digitoxin analogs that includes compounds with significantly enhanced cytotoxic potency toward human cancer cells and tumor-specificity, but are less potent Na + /K + -ATPase inhibitors in a human cell line than digitoxin.
• CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS
  申请人：The Regents of the University of California

  公开号：US20170016040A1

  公开（公告）日：2017-01-19

  The present invention provides a one-pot multi-enzyme method for preparing UDP-sugars from simple sugar starting materials. The invention also provides a one-pot multi-enzyme method for preparing oligosaccharides from simple sugar starting materials.
• US7361745B2
  申请人：——

  公开号：US7361745B2

  公开（公告）日：2008-04-22