2-氧代戊二酸 | 27280-85-9

• 物质功能分类: 生物化工 - 生化试剂 - 维生素
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 2-氧代戊二酸
• 英文名称: 2-oxoglutaric acid, compound with 5-hydroxy-6-methylpyridine-3,4-dimethanol (1:1)
• 英文别名: Pyridoxin-α-oxoglutarat；Pyridoxine alpha-Ketoglutarate；4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;2-oxopentanedioic acid
• CAS: 27280-85-9
• 化学式: C₅H₆O₅*C₈H₁₁NO₃
• 分子量: 315.28
• InChiKey: MLAUVUHGQARGDU-UHFFFAOYSA-N

物化性质

• 熔点：
  120.5-121.5 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -0.41
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  165
• 氢给体数：
  5
• 氢受体数：
  9

安全信息

• 海关编码：
  2933399090

文献信息

• Method, composition and device for treating starch related diseases
  申请人：Arbab Sayed Mustafa Tarig

  公开号：US20050221406A1

  公开（公告）日：2005-10-06

  The present invention includes a method of diagnosing an insulin resistant mammal including the steps of obtaining one or more samples for testing; and determining the level of starch in the one or more samples, whereby the presence of starch correlates with insulin resistant.

  本发明包括一种诊断胰岛素抵抗哺乳动物的方法，包括以下步骤：获取一个或多个样本进行检测；确定一个或多个样本中的淀粉水平，其中淀粉的存在与胰岛素抵抗相关。
• FOOD AND FEEDSTUFF
  申请人：JUNGVID, Hans

  公开号：EP0541524B1

  公开（公告）日：1996-10-23
• IMPROVED SUSTAINED ENERGY AND ANABOLIC COMPOSITION
  申请人：METAGENICS, INC.

  公开号：EP0651617B1

  公开（公告）日：2000-10-25
• METHOD OF USE OF VITAMIN K AS ENERGY ENHANCER IN DIVERSE DISEASE STATES
  申请人：Viridis Biopharma Pvt Ltd.

  公开号：EP2405906A2

  公开（公告）日：2012-01-18
• Method of Use of Vitamin K as Energy Enhancer in Diverse Disease States
  申请人：Mehta Dilip S

  公开号：US20120149780A1

  公开（公告）日：2012-06-14

  The invention relates to Vitamin K, its derivatives and combinations to increase the energy levels in diverse disease states and life style disorders, which are characterized by low energy level due to inadequate VO2 max , and pO 2 and low availability of ATP molecules. VO 2max , peak oxygen uptake, is intimately connected to several diseases and life style disorders such as Metabolically Obese but Normal Weight (MONW), Overweight/Obese, diabetes mellitus, coronary artery disease, hypertension, cerebral vascular insufficiency, immune deficient states, cancer, aging-related disorders, reduced cardiopulmonary reserves and muscular fitness in athletics, high altitude climbing and exercise. The invention discloses that innovative blends of components that, in unique combination, synergistically bestow enhancement of VO 2max leading to higher energy level, less fatigability and energy adaptations to stressful stimuli in humans and animals. Thus, vitamin K, its derivatives and combinations enhance the energy availability, primarily by the activation of AMP protein kinase (AMPK).