1-cyanocarbazole | 31892-43-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-cyanocarbazole
• 英文别名: 4-cyanocarbazole；carbazole-4-carbonitrile；4-Carbazol-carbonitril；Carbazol-4-carbonitril；9H-Carbazole-4-carbonitrile
• CAS: 31892-43-0
• 化学式: C₁₃H₈N₂
• 分子量: 192.22
• InChiKey: FXFRNGBHSNZMQR-UHFFFAOYSA-N

物化性质

• 沸点：
  437.8±18.0 °C(Predicted)
• 密度：
  1.29±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.6
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-cyanocarbazole 在 titanium(IV) isopropylate 、 盐酸 、 4-二甲氨基吡啶 、 1-羟基苯并三唑 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三乙胺 作用下， 以 四氢呋喃 、 乙醚 、 二氯甲烷 、 乙酸乙酯 为溶剂， 反应 22.33h， 生成 N-(1-(9H-carbazol-4-yl)cyclopropyl)-5-(2-(dimethylamino)ethoxy)-2-methylbenzamide hydrochloride
  参考文献：
  名称：

  [EN] COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES
  [FR] COMPOSÉS ET MÉTHODES DE TRAITEMENT DES CORONAVIRUS

  摘要：

  This invention provides compounds for the inhibition of papain-like proteases (PLpros) for the inhibition of viruses, including compounds of formula (I"), and pharmaceutically acceptable salts thereof.

  公开号：

  WO2023064493A1
• 作为产物：
  描述：

  9-azidophenanthridine 生成 1-cyanocarbazole
  参考文献：
  名称：

  WENTRUP C.; WINTER H.-W., J. AMER. CHEM. SOC., 1980, 102, NO 19, 6159-6161

  摘要：

  DOI：

文献信息

• One-electron photooxidation of carbazole in the presence of carbon tetrachloride. Part II. Carbon tetrachloride as a reaction medium. Use of ammonia after irradiation and during irradiation
  作者：Bogumil Zelent、Gilles Durocher

  DOI：10.1139/v82-353

  日期：1982.10.1

  In part I of this series of papers we proposed the mechanism of electron transfer as the primary photochemical reaction in the carbazole – carbon tetrachloride system along with a secondary photochemical reaction initiated by transformations of the radical cation of carbazole in the solvent cage resulting in intermediates:In this paper we discuss the influence of ammonia, used after and during irradiation

  在本系列论文的第一部分中，我们提出了电子转移的机理，作为咔唑 - 四氯化碳体系中的主要光化学反应，以及由咔唑自由基阳离子在溶剂笼中的转化引发的二次光化学反应，产生中间体：在本文中，我们讨论了辐照后和辐照期间使用的氨对二次转化机制和所研究系统中热力学稳定产物形成的影响。N-氰基咔唑、1-氰基咔唑和3-氰基咔唑等化合物已作为氨气中和光电解液的主要产物形成。这些化合物的形成机制可以通过氨与阳离子α和γi的化学反应来解释。
• Seven-membered ring compounds
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：US10968229B2

  公开（公告）日：2021-04-06

  The present invention relates to compounds of formula (I); a process for their production and their use in electronic devices, especially electroluminescent devices. When used as charge transport material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency, stability, manufacturability and/or spectral characteristics of electroluminescent devices.

  本发明涉及式（I）化合物；其生产工艺及其在电子设备，特别是电致发光设备中的用途。当用作电致发光器件中电荷传输材料和/或磷光发光体的主材料时，式 I 化合物可提高电致发光器件的效率、稳定性、可制造性和/或光谱特性。
• 9-Azidoacridine and 9-acridinylnitrene
  作者：Avat Arman Taherpour、David Kvaskoff、Paul V. Bernhardt、Curt Wentrup

  DOI：10.1002/poc.1657

  日期：——

  AbstractMatrix photolysis as well as flash vacuum thermolysis (FVT) of 9‐azidoacridine affords 9‐acridinylnitrene, which is characterized by its IR and ESR spectra and is photochemically inert. FVT above 600 °C yields a mixture of the five isomeric cyanocarbazoles. Microwave‐assisted reaction with diethyl‐ and dipropylamines in solution affords acridinylformamidine and acridinylpropionamidine, respectively. Microwave‐assisted reaction with dimethylamine causes nucleophilic displacement of the azido group. Microwave‐assisted 1,3‐dipolar cycloaddition with phenylacetylene yields the two regioisomeric 9‐(4‐ and 5‐phenyl‐1,2,3‐triazol‐1‐yl)acridines, whose structures were established by X‐ray crystallography. Copyright © 2010 John Wiley & Sons, Ltd.
• Microwave-assisted synthesis of functionalized carbazoles <i>via</i> palladium-catalyzed aryl C–H activation and study of their interactions with calf-thymus DNA
  作者：Safiul Alam、Rejaul Karim、Aminur Khan、Asifur Rahaman Mallick、Nayim Sepay、Soumen Ghosh

  DOI：10.1080/00397911.2022.2116344

  日期：2022.9.17
• 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS)
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：US20170362241A1

  公开（公告）日：2017-12-21

  The present invention relates to compounds of formula(I), a process for their production and their use in electronic devices, especially electroluminescent devices. When used as charge transport material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency and reduced driving voltage of electroluminescent devices.