trans-1-(1-Methylethylidene)-2-isopropyl-3-methylcyclopropane | 24524-51-4

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: trans-1-(1-Methylethylidene)-2-isopropyl-3-methylcyclopropane
• 英文别名: Propane, 2-(2-isopropylidene-3-methylcyclopropyl)-, trans-；(1R,2R)-1-methyl-2-propan-2-yl-3-propan-2-ylidenecyclopropane
• CAS: 24524-51-4
• 化学式: C₁₀H₁₈
• 分子量: 138.253
• InChiKey: YMHRHZGFRVCIFH-RKDXNWHRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  反-4-甲基-2-戊烯 、 Phenyl-(2-methylprop-1-enyl)iodonium tetrafluoroborate 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 以12%的产率得到trans-1-(1-Methylethylidene)-2-isopropyl-3-methylcyclopropane
  参考文献：
  名称：

  Nature of Alkylidenecarbenes Generated from Alkenylphenyliodonium Tetrafluoroborates via Base-Induced .alpha.-Elimination

  摘要：

  DOI：

  10.1021/jo00113a051

文献信息

• Reaction of dimethylethylidenecarbene with olefins
  作者：Melvin S. Newman、Timothy B. Patrick

  DOI：10.1021/ja01051a048

  日期：1969.11
• Alkylidenecarbenes from 1-diazo-1-alkenes: their electrophilicity and stereochemistry of [2 + 2]-cycloaddition
  作者：John C. Gilbert、David H. Giamalva

  DOI：10.1021/jo00041a024

  日期：1992.7

  Determination of the rho-value for the [2 + 2]-cycloaddition of the alkylidenecarbene derived from 1-diazo-2-methyl-1-propene shows that the carbene has an electrophilicity comparable to that of the species derived from alpha-elimination of the corresponding vinyl triflate. Measurements of rho as a function of solvent indicate that the carbene is free of encumbrance with solvent molecules, at least in the sense that the latter are functioning as Lewis bases. The observed stereochemistry of the [2 + 2]-cycloaddition is consistent with the alkylidenecarbene being produced in a singlet electronic state.
• Nature of Alkylidenecarbenes Generated from Alkenylphenyliodonium Tetrafluoroborates via Base-Induced .alpha.-Elimination
  作者：Masahito Ochiai、Takuya Sueda、Koji Uemura、Yukio Masaki

  DOI：10.1021/jo00113a051

  日期：1995.4