indolizine-1,2,3-triyltris((4-nitrophenyl)methanone) | 143718-67-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: indolizine-1,2,3-triyltris((4-nitrophenyl)methanone)
• 英文别名: [2,3-Bis(4-nitrobenzoyl)indolizin-1-yl]-(4-nitrophenyl)methanone
• CAS: 143718-67-6
• 化学式: C₂₉H₁₆N₄O₉
• 分子量: 564.467
• InChiKey: YPQOPHPVGIKBRU-UHFFFAOYSA-N

物化性质

• 熔点：
  276-277 °C
• 密度：
  1.50±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  42
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  193
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  4-nitrophenacylpyridinium bromide 在 tetrakis(pyridine)cobalt(II) dichromate 、 Py₄Co(HCrO₄)2 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.5h， 以34%的产率得到indolizine-1,2,3-triyltris((4-nitrophenyl)methanone)
  参考文献：
  名称：

  A Facile Preparation of 1,2,3-Triaroylindolizines

  摘要：

  Fourteen 1,2,3-triaroylindolizines were prepared conveniently by oxidation of corresponding N-aracyl pyridinium or substituted pyridinium bromides with a versatile oxidant TPCD [(Py4Co(HCrO4)2, tetrakis-pyridino-cobalt (II) dichromate] in 12-42 % yields.

  DOI：

  10.1080/00397919208021344

文献信息

• Convergent domino synthesis of 1,2,3-triaroylindolizines from methyl ketones and pyridines via self-division of labor strategy
  作者：Yan Yang、Meng Gao、Dong-Xue Zhang、Liu-Ming Wu、Wen-Ming Shu、An-Xin Wu

  DOI：10.1016/j.tet.2012.06.091

  日期：2012.9

  A highly efficient method for the synthesis of 1,2,3-triaroylindolizines has been established from readily available methyl ketones and pyridines in the presence of iodine. This reaction also examplified the self-division of labor strategy in convergent domino synthesis. (C) 2012 Elsevier Ltd. All rights reserved.
• A Facile Preparation of 1,2,3-Triaroylindolizines
  作者：Xudong Wei、Yuefei Hu、Tingsheng Li、Hongwen Hu

  DOI：10.1080/00397919208021344

  日期：1992.7

  Fourteen 1,2,3-triaroylindolizines were prepared conveniently by oxidation of corresponding N-aracyl pyridinium or substituted pyridinium bromides with a versatile oxidant TPCD [(Py4Co(HCrO4)2, tetrakis-pyridino-cobalt (II) dichromate] in 12-42 % yields.