α-D-glucosyl pyrophosphate | 92642-57-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-D-glucosyl pyrophosphate
• 英文别名: Diphosphoric acid 1-alpha-d-glucopyranosyl ester；phosphono [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
• CAS: 92642-57-4
• 化学式: C₆H₁₄O₁₂P₂
• 分子量: 340.117
• InChiKey: GHRQAEPJQRJDHX-VFUOTHLCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.8
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  203
• 氢给体数：
  7
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  alpha-D-半乳糖 生成 α-D-glucosyl pyrophosphate
  参考文献：
  名称：

  TSUHAKO, MITSUTOMO;SUEYOSHI, CHIYOKO;BABA, YOSHINOBU;MIYAJIMA, TOHORU;OHA+, CHEM. LETT.,(1987) N 7, 1431-1434

  摘要：

  DOI：

文献信息

• Synthesis of polyprenyl pyrophosphate sugars from unprotected mono- and oligo-saccharide phosphates
  作者：Leonid L. Danilov、Sergei D. Maltsev、Vladimir N. Shibaev、Nikolai K. Kochetkov

  DOI：10.1016/s0008-6215(00)85534-2

  日期：1981.2
• TSUHAKO, MITSUTOMO;SUEYOSHI, CHIYOKO;BABA, YOSHINOBU;MIYAJIMA, TOHORU;OHA+, CHEM. LETT.,(1987) N 7, 1431-1434
  作者：TSUHAKO, MITSUTOMO、SUEYOSHI, CHIYOKO、BABA, YOSHINOBU、MIYAJIMA, TOHORU、OHA+

  DOI：——

  日期：——
• [EN] GLYCORANDOMIZATION AND THE PRODUCTION OF NOVEL ERYTHRONOLIDE AND COUMARIN ANALOGS<br/>[FR] GLYCORANDOMISATION ET PRODUCTION DE NOUVEAUX ANALOGUES D'ERYTHRONOLIDE ET DE COUMARINE
  申请人：SLOAN KETTERING INST CANCER

  公开号：WO2002079150A2

  公开（公告）日：2002-10-10

  The present invention provides combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural secondary metabolites, or one which is putatively associated with or involved in production of natural secondary metabolites. The glycosyltransferase may show significant flexibility with respect to its NDP-sugar donors and/or its aglycons. NDP-sugar donors may be commercially available, or may be produced by utilizing mutant or wild type nucleotidyltransferases significant flexibility with respect to their substrates.