3-(Hydroxymethyl)-5-octoxyphenol | 872576-14-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(Hydroxymethyl)-5-octoxyphenol
• CAS: 872576-14-2
• 化学式: C₁₅H₂₄O₃
• 分子量: 252.354
• InChiKey: ZQFAKBGVUOIGRA-UHFFFAOYSA-N

物化性质

• 沸点：
  418.2±30.0 °C(Predicted)
• 密度：
  1.046±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(Hydroxymethyl)-5-octoxyphenol 在 18-冠醚-6 、 potassium tert-butylate 、 potassium carbonate 、 pyridinium chlorochromate 、 sodium iodide 作用下， 以 四氢呋喃 、 二氯甲烷 、 丙酮 为溶剂， 反应 45.33h， 生成 (3-Octyloxy-5-vinyl-phenoxy)-acetic acid tert-butyl ester
  参考文献：
  名称：

  Homopolymer Micelles in Heterogeneous Solvent Mixtures

  摘要：

  Amphiphilic homopolymers containing a hydrophilic and a hydrophobic functionality in each monomer unit have been shown to form polar or apolar containers depending on the solvent environment. When presented with a mixture of solvents, these polymeric containers are capable of releasing certain guest molecules. The fundamental mechanism behind these properties is investigated, and the utility of these assemblies in separations has been demonstrated with an example.

  DOI：

  10.1021/ja056042a
• 作为产物：
  描述：

  二羟基苯甲酸乙酯 在 lithium aluminium tetrahydride 、 18-冠醚-6 、 potassium carbonate 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 19.5h， 生成 3-(Hydroxymethyl)-5-octoxyphenol
  参考文献：
  名称：

  Homopolymer Micelles in Heterogeneous Solvent Mixtures

  摘要：

  Amphiphilic homopolymers containing a hydrophilic and a hydrophobic functionality in each monomer unit have been shown to form polar or apolar containers depending on the solvent environment. When presented with a mixture of solvents, these polymeric containers are capable of releasing certain guest molecules. The fundamental mechanism behind these properties is investigated, and the utility of these assemblies in separations has been demonstrated with an example.

  DOI：

  10.1021/ja056042a

文献信息

• Invertible amphiphilic polymers
  申请人：Thayumanavan Sankaran

  公开号：US20070293669A1

  公开（公告）日：2007-12-20

  Amphiphilic monomeric compounds and corresponding homopolymers and copolymers capable of assembly and invertible configuration in introduction to and change in fluid medium.

  具有两性单体化合物及相应的同聚物和共聚物能够在流体介质中进行组装和可逆配置。
• US7687600B2
  申请人：——

  公开号：US7687600B2

  公开（公告）日：2010-03-30
• Homopolymer Micelles in Heterogeneous Solvent Mixtures
  作者：Subhadeep Basu、Dharma Rao Vutukuri、S. Thayumanavan

  DOI：10.1021/ja056042a

  日期：2005.12.1

  Amphiphilic homopolymers containing a hydrophilic and a hydrophobic functionality in each monomer unit have been shown to form polar or apolar containers depending on the solvent environment. When presented with a mixture of solvents, these polymeric containers are capable of releasing certain guest molecules. The fundamental mechanism behind these properties is investigated, and the utility of these assemblies in separations has been demonstrated with an example.