3-perfluorohexyl propanoyl chloride | 127526-16-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 3-perfluorohexyl propanoyl chloride
• 英文别名: 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononan-1-oyl chloride；4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononanoyl Chloride
• CAS: 127526-16-3
• 化学式: C₉H₄ClF₁₃O
• 分子量: 410.562
• InChiKey: NNQFVPKMNPOCBP-UHFFFAOYSA-N

物化性质

• 沸点：
  183.1±35.0 °C(Predicted)
• 密度：
  1.599±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  3-perfluorohexyl propanoyl chloride 在 叠氮基三甲基硅烷 作用下， 生成 2-perfluorohexyl ethyl isocyanate
  参考文献：
  名称：

  在微图案金基底上通过电聚合产生的仿生玫瑰花瓣样基底。

  摘要：

  具有高水粘附性的表面是用于水处理和管理领域中不同应用的有前途的材料，例如用于集水系统或油/水分离膜。在这里，我们开发了玫瑰花瓣状的底物，表现出有趣的疏水性。这种生物启发的材料通过两个制造步骤的组合来模仿天然基材：（1）进行微图案化以形成由方柱组成的微结构镀金基材；（2）电聚合过程在微柱上产生纳米结构。明智地选择微图案化规格（柱直径和螺距），可电聚合单体的类型以及电化学参数，可制成既具有极高的水接触角（高达160°）的材料，同时保持了很高的水附着力。我们的研究表明，如我们在接触角测量中所观察到的，复合界面由微柱上的Wenzel状态和柱之间的Cassie-Baxter状态（“ Cassie填充的纳米结构”）表示。实际上，我们表明，节距应该很小，以获得最佳的微柱表面密度。此外，为了仅用纳米结构涂覆方柱，优选约50mCcm-2的相对低的沉积电荷。如我们在接触角测量中所观察到的。实际上，我们表明，节

  DOI：

  10.1002/cplu.201600387
• 作为产物：
  描述：

  4,4,5,5,6,6,7,7,8,8,9,9,9-十三氟壬酸 在 氯化亚砜 作用下， 反应 12.0h， 生成 3-perfluorohexyl propanoyl chloride
  参考文献：
  名称：

  热晶形金属清除剂：高度氟化的酮的合成和多核NMR研究及其在重金属去除中的应用

  摘要：

  通过全氟烷基锌试剂与全氟酰氯的偶合反应报道了具有两个长链全氟烷基的酮的制备。在从水溶液中异质去除重金属M 2+（M = Sn，Cd，Pb，Hg）和As 5+以及使用氟代酮独特的热定型性质从有机溶剂中去除这些金属的过程中，已经研究了该酮。 。此外，对合成中的一种中间体2H，2H，3H，3H-全氟酸的全面13 C NMR研究使得所有1 J C–F和2 J C–F的测定都得以进行。耦合常数。还报告了酸CF 3（CF 2）5 CH 2 CH 2 CO 2 H的晶体结构。

  DOI：

  10.1016/j.jfluchem.2010.02.004

文献信息

• Selective mono- and di{(perfluoroalkyl)acylation} of ferrocene
  作者：David Hazafy、Marie Sobociková、Petr Štěpnička、Jiřı́ Ludvı́k、Martin Kotora

  DOI：10.1016/j.jfluchem.2003.08.002

  日期：2003.12

  The selective synthesis of mono- and 1,1′-di(perfluoroalkyl)acylated} ferrocenes by Friedel–Crafts acylation with (perfluoroalkyl)acyl halides is described. The acyl derivatives were further converted to the corresponding (perfluoroalkyl)alkyl ferrocenes by reduction of the carbonyl group with LiAlH4/AlCl3. Electrochemical studies of all the obtained substituted ferrocenes were carried out to assess

  描述了通过用（全氟烷基）酰基卤进行的弗瑞德-克拉夫茨（Friedel-Crafts）酰化作用来选择性合成单-和1,1'-二（全氟烷基）酰化}二茂铁。通过用LiAlH 4 / AlCl 3还原羰基，将酰基衍生物进一步转化为相应的（全氟烷基）烷基二茂铁。对所有获得的取代的二茂铁进行了电化学研究，以评估全氟烷基马尾辫对其氧化还原行为的影响。
• Bifunctionalized Monomers for Surfaces with Controlled Hydrophobicity
  作者：Rawia Ben Trad、Emna El Kout、Mejda El Kateb、Mohammed Beji、Jean-Pierre Laugier、Guilhem Godeau、Frédéric Guittard、Thierry Darmanin

  DOI：10.1002/cplu.201700256

  日期：2017.10

  The control of surface wettability is a key parameter for many application fields (materials, biomedical engineering, etc.). In this work, a new and efficient strategy to synthesize monomers suitable for hydrophobic surface elaboration is reported. This original approach allows the preparation of monomers and, as a consequence, surfaces bearing two different substituents by using the Staudinger reductive

  表面润湿性的控制是许多应用领域（材料，生物医学工程等）的关键参数。在这项工作中，报告了一种新的有效策略来合成适用于疏水表面修饰的单体。该原始方法允许通过使用施陶丁格还原胺化和酰胺化来制备单体，并因此制备带有两个不同取代基的表面。通过电聚合制备粗糙的导电聚合物膜。此处报道的原始表面是具有可调疏水特征的高度结构化表面。根据接枝链的不同，表面是亲水的（PEDOT-Benz-Ph，θ= 80°； PEDOT =聚（3,4-乙撑二氧噻吩）），疏水的（PEDOT-Benz-C12，θ= 132°），甚至超疏水性（PEDOT-Benz-F8，θ= 152°（α= 5.0°，H = 0.3°）。
• Synthesis of Polymerizable Double-Chain Glycolipids derived from Tris. Polymerization in aqueous Media. Preliminary Investigation of their Colloidal Behavior
  作者：Ange Polidori、Olivier Braun、Nathalie Mora、Bernard Pucci*

  DOI：10.1016/s0040-4039(97)00413-9

  日期：1997.4

  A series of mono and double tailed hydro and perfluorocarbon surfactant derived from Tris(hydroxymethyl)aminomethane and bearing an acryloyl moiety on the hydrophilic head have been prepared. The bicodal surfactants dispersed in water by ultrasonication formed vesicles which precipitated after UV irradiation. We describe a new method to stabilize these vesicular dispersions during the polymerization

  制备了一系列衍生自三（羟甲基）氨基甲烷并在亲水头上带有丙烯酰基部分的单尾和双尾氢和全氟化碳表面活性剂。通过超声处理分散在水中的双水合表面活性剂形成囊泡，该囊泡在紫外线照射后沉淀。我们描述了一种通过添加单壳两亲物来稳定聚合过程中稳定这些水泡分散体的新方法。©1997由Elsevier Science Ltd发布。
• Enhanced activity of fluorinated quaternary ammonium surfactants against Pseudomonas aeruginosa
  作者：Lionel Massi、Frederic Guittard、Richard Levy、S. Géribaldi

  DOI：10.1016/j.ejmech.2008.07.032

  日期：2009.4

  A novel series of fluorinated quaternary bisammonium surfactants has been synthesized in view to optimize their antimicrobial activities against Pseudomonas aeruginosa. As compared with commercial references, most of the new surfactants synthesized exhibit an enhanced activity which is discussed as a function of the nature of the spacer group between the quaternized nitrogen atoms and of the nature of the connector function between the nitrogen atoms and the perfluorinated carbon chains. It appears that the fluorinated "Gemini" surfactants bearing an amide connector can be an interesting alternative to hydrocarbon ammonium salts as preservatives and disinfectants against R aeruginosa. (c) 2008 Elsevier Masson SAS. All rights reserved.
• Stabilization of polymerized vesicular systems: an application of the dynamic molecular shape concept
  作者：Michel Wathier、Ange Polidori、Karine Ruiz、Anne-Sylvie Fabiano、Bernard Pucci

  DOI：10.1016/s0009-3084(02)00006-3

  日期：2002.5

  A series of glycolipid surfactants derived from Tris(hydroxymethyl)acrylamidomethane (THAM) and bearing hydrocarbon or perfluorocarbon tails and an acryloyl group attached to their polar head was prepared to explore the aqueous behavior of the supramolecular systems they form. The dispersion Of surfactants was achieved in water under ultrasonication conditions. Hydrocarbon Compounds give heterogeneous vesicular assemblies. In the case of perfluorocarbon derivatives homogeneous vesicles were obtained. However after Way storage, all these systems fuse. To stabilize these vesicles, polymerization by ultra violet (UV) irradiation was carried Out. During this reaction, a precipitation in water was observed for the hydrocarbon surfactants, whereas fluorocarbon Structures provide stable vesicles Without any alteration of their size. According to these results, the polymerization process was achieved, in the case of hydrocarbon glycolipid, in the presence of different cosurfactants bearing a single hydrocarbon tail or a polyhydroxylated head and a cholesterol terminus. In Such conditions, homogeneous stable vesicles were prepared. Moreover, the THAM derived telomers bearing a cholesterol terminus were able to stabilize and reduce the size of vesicles formed with synthetic glycolipid surfactants. The drug encapsulation ability of these systems was investigated by measurement of the release kinetics of a fluorescent dye, carboxyfluorescein (CF), before and after polymerization. (C) 2002 Published by Elsevier Science Ireland Ltd.