5-methoxy-1-azaanthracene-9,10-dione | 101402-88-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-methoxy-1-azaanthracene-9,10-dione
• 英文别名: 6-methoxybenzo[g]quinoline-5,10-dione
• CAS: 101402-88-4
• 化学式: C₁₄H₉NO₃
• 分子量: 239.23
• InChiKey: NLRHQAXUKWLSBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  56.3
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dichlorotricarbonylruthenium(II) dimer 、 5-methoxy-1-azaanthracene-9,10-dione 以 乙醇 为溶剂， 以34%的产率得到[Ru(CO)2Cl2(6-methoxybenzo[g]quinoline-5,10-dione)]
  参考文献：
  名称：

  Synthesis, structure and properties of ruthenium(II) complexes with quinolinedione derivatives as chelate ligands: Crystal structure of [Ru(CO)2Cl2(6-methoxybenzo[g]quinoline-5,10-dione)]

  摘要：

  The reaction of the dimer complex [{Ru(CO)(3)Cl-2}(2)] with the ligands 4,6-dichloroquinoline-5,8-dione and 6-methoxybenzo[g]quinoline-5, 10-dione in ethanol solution led to the neutral mononuclear complexes of general formula [Ru(CO)(2)Cl-2(kappa(2)-quinolinedione-N,O)]. The complexes were characterized by elemental analysis, IR and RMN spectroscopy, and the molecular structure of [Ru(CO)(2)Cl-2(6-methoxybenzo[g]quinoline-5,10-dione)] was determined by single-crystal X-ray diffraction. The redox chemistry of ligands and complexes was investigated by cyclic voltammetry, and their potential antitumor activity was also evaluated. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2007.08.014
• 作为产物：
  描述：

  5,8-喹啉二酮 、 1-甲氧基-1,3-环己二烯 生成 5-methoxy-1-azaanthracene-9,10-dione
  参考文献：
  名称：

  POTTS K. T.; BHATTACHARJEE D.; WALSH E. B., J. ORG. CHEM., 51,(1986) N 11, 2011-2021

  摘要：

  DOI：

文献信息

• Cycloaddition routes to azaanthraquinone derivatives. 1. Use of azadienophiles
  作者：kevin T. Potts、Debkumar Bhattacharjee、Eileen B. Walsh

  DOI：10.1021/jo00361a014

  日期：1986.5
• POTTS K. T.; BHATTACHARJEE D.; WALSH E. B., J. ORG. CHEM., 51,(1986) N 11, 2011-2021
  作者：POTTS K. T.、 BHATTACHARJEE D.、 WALSH E. B.

  DOI：——

  日期：——
• Synthesis, structure and properties of ruthenium(II) complexes with quinolinedione derivatives as chelate ligands: Crystal structure of [Ru(CO)2Cl2(6-methoxybenzo[g]quinoline-5,10-dione)]
  作者：Yolanda Prieto、Marcelo Muñoz、Verónica Arancibia、Mauricio Valderrama、Fernando J. Lahoz、M. Luisa Martín

  DOI：10.1016/j.poly.2007.08.014

  日期：2007.11

  The reaction of the dimer complex [Ru(CO)(3)Cl-2}(2)] with the ligands 4,6-dichloroquinoline-5,8-dione and 6-methoxybenzo[g]quinoline-5, 10-dione in ethanol solution led to the neutral mononuclear complexes of general formula [Ru(CO)(2)Cl-2(kappa(2)-quinolinedione-N,O)]. The complexes were characterized by elemental analysis, IR and RMN spectroscopy, and the molecular structure of [Ru(CO)(2)Cl-2(6-methoxybenzo[g]quinoline-5,10-dione)] was determined by single-crystal X-ray diffraction. The redox chemistry of ligands and complexes was investigated by cyclic voltammetry, and their potential antitumor activity was also evaluated. (C) 2007 Elsevier Ltd. All rights reserved.