2-methyl-hept-3-en-2-ol | 116668-45-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-methyl-hept-3-en-2-ol
• 英文别名: 2-methylhept-3-en-2-ol
• CAS: 116668-45-2
• 化学式: C₈H₁₆O
• 分子量: 128.214
• InChiKey: CTYHBWWYKXFNAV-UHFFFAOYSA-N

物化性质

• 熔点：
  -31.5°C (estimate)
• 沸点：
  202.67°C (estimate)
• 密度：
  0.8646 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-甲基-2-庚烯 在 oxygen 、 硫堇(劳氏紫) 、 三苯基膦 作用下， 以 正己烷 为溶剂， 反应 3.0h， 生成 2-甲基-1-庚烯-3-醇 、 2-methyl-hept-3-en-2-ol
  参考文献：
  名称：

  沸石基质辅助单线态氧敏化剂在光氧化过程中的分解

  摘要：

  噻嗪染料，如硫氨酸，亚甲基蓝和亚甲基绿在单价阳离子交换Y型沸石中交换。取决于水含量，染料分子以单体（“干”）或二聚体（“湿”）的形式存在。单体染料可有效地通过沸石腔内的能量转移过程产生单线态氧。在诸如LiY的极性沸石中，NaY的能量转移占主导地位，而在诸如CsY的碱性沸石中，电子转移会超过能量转移，从而导致染料的光解。虽然在短时间照射下，能量转移到氧气上会导致产物分布的选择性，但在长时间照射下，通过电子转移破坏染料是主要结果。

  DOI：

  10.1016/j.jphotochem.2016.02.010

文献信息

• γ-Alumina-supported [60]fullerene catalysts: Synthesis, properties and applications in the photooxidation of alkenes
  作者：Manolis D. Tzirakis、John Vakros、Loukia Loukatzikou、Vasilis Amargianitakis、Michael Orfanopoulos、Christos Kordulis、Alexis Lycourghiotis

  DOI：10.1016/j.molcata.2009.10.001

  日期：2010.2.1

  Immobilization of [60]fullerene onto gamma-Al2O3 surface provides new heterogeneous photocatalysts for the oxidation of organic Compounds under oxygen atmosphere. These catalysts have been prepared by simple or Successive incipient wetness impregnation (using an organic solvent) followed by air-heating at 180 degrees C. In the C-60/Al2O3 system. C-60 loading was varied in the range of 1-4% (w/w). Several experimental techniques including BET. XRD, DRS, TGA, microelectrophoresis, photoluminescence and kinetic extraction, have been used to characterize these catalytic materials. It was found that the quite high surface exposed by the supported C-60 increases with the amount of the supported C-60, while the dispersion of the supported C-60 decreases. The quite stable supported [60]fullerene phase is comprised from C-60 clusters, small and large aggregates. This non-uniform size distribution is reflected to a non-uniform distribution concerning the 'supported phase-support' interactions. These interactions decrease with the amount of the supported C-60. The photocatalysts prepared may be safely used Lip to 200 degrees C. Above this temperature the supported C-60 is sublimated/combusted in air.The photocatalytic activity of the so-obtained catalytic systems has been evaluated in terms of substrate conversion in the singlet oxygen 'ene' reaction of alkenes. The photooxygenation of 2-methyl-2-heptene has been examined as a probe reaction. It was round that the catalytic activity increases with the increasing amount of the supported C-60 up to the value of 3% (w/w) and then decreases. The intrinsic activity expressed as TON or TOF decreased monotonically with C-60. In all cases, however. the photocatalytic activity of the Al2O3-supported C-60 catalysts was substantially increased compared to the unsupported C-60 precursor, exhibiting quantitative conversion yields after short reaction times. The catalytic behavior was attributed to the aforementioned opposite trends which follow the surface exposed by the supported C-60 on one hand and the 'supported C-60-support' interactions and the C-60 dispersion on the other hand. The easy separation of these solid catalysts from the reaction mixture, the high activity and stability as well as the retained activity in subsequent catalytic cycles. make these supported catalysts suitable for a small-scale synthesis. (C) 2009 Elsevier B.V. All rights reserved.
• Compositions and Methods for Cancer Treatment
  申请人：Swamy Narasimha

  公开号：US20100144671A1

  公开（公告）日：2010-06-10

  Bromoacetoxycalcidiol (B3CD), which is structurally related to calcidiol, exhibits cytotoxic and apoptotic activity toward cancer cells, including highly aggressive neuroblastoma cells. A series of small molecules designed around the structure of B3CD is expected to have growth inhibitory and apoptogenic activities toward a wide range of malignancies. B3CD shows no apparent toxicity in vivo, indicating potential value as a chemotherapeutic agent which will be particularly useful in treating highly aggressive tumors.
• Zeolite matrix assisted decomposition of singlet oxygen sensitizers during photooxidation
  作者：J. Shailaja、J. Sivaguru、V. Ramamurthy

  DOI：10.1016/j.jphotochem.2016.02.010

  日期：2016.12

  monomeric dye is effective in producing singlet oxygen by energy transfer process inside the zeolite cavity. In polar zeolites like LiY, NaY energy transfer predominates whereas in basic zeolites like CsY electron transfer overtakes the energy transfer leading to the photo-destruction of the dye. While on short time of irradiation, energy transfer to oxygen led to selectivity in the product distribution

  噻嗪染料，如硫氨酸，亚甲基蓝和亚甲基绿在单价阳离子交换Y型沸石中交换。取决于水含量，染料分子以单体（“干”）或二聚体（“湿”）的形式存在。单体染料可有效地通过沸石腔内的能量转移过程产生单线态氧。在诸如LiY的极性沸石中，NaY的能量转移占主导地位，而在诸如CsY的碱性沸石中，电子转移会超过能量转移，从而导致染料的光解。虽然在短时间照射下，能量转移到氧气上会导致产物分布的选择性，但在长时间照射下，通过电子转移破坏染料是主要结果。