2-氰基丙烯酸戊酯 | 6701-15-1

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-氰基丙烯酸戊酯
• 英文名称: n-pentyl 2-cyanoacrylate
• 英文别名: Pentyl 2-cyanoacrylate；pentyl 2-cyanoprop-2-enoate
• CAS: 6701-15-1
• 化学式: C₉H₁₃NO₂
• 分子量: 167.208
• InChiKey: SXRFXXNXVPFXDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHODS OF TREATING A BLOOD VESSEL
  申请人：Kerber Charles W.

  公开号：US20090137981A1

  公开（公告）日：2009-05-28

  Described herein are methods for treating a blood vessel. In an embodiment, the method of treating a blood vessel comprises providing at least one manipulable tool in a blood vessel, depositing a non-solid polymerizable material into a deposition area of the vessel, wherein the polymerizable liquid hardens over time upon contact with blood in the blood vessel, and altering the shape of the polymerizable material while it hardens by manipulating the tool.

  描述了治疗血管的方法。在一个实施例中，治疗血管的方法包括在血管中提供至少一个可操作的工具，将非固体聚合材料沉积到血管的沉积区，其中聚合液体在与血管中的血液接触后随时间硬化，并通过操作工具在材料硬化时改变其形状。
• SINGLE VIAL FORMULATION FOR MEDICAL GRADE CYANOACRYLATE
  申请人：Kerber Charles W.

  公开号：US20090257976A1

  公开（公告）日：2009-10-15

  Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.

  烷基氰基丙烯酸酯组合物及制备这些组合物的方法，利用高纯度单体起始材料，形成更粘稠的寡聚物，并与增塑剂和抑制剂结合，以提供单容器、储存稳定的医用氰基丙烯酸酯。
• RAPIDLY CURING CYANOACRYLATES AS ADHESIVES
  申请人：Swords Noeleen

  公开号：US20100029978A1

  公开（公告）日：2010-02-04

  The present invention relates to a polymerizable adhesive composition which comprises, at least as one constituent, a cyanacrylate component and which requires a comparitively short time for curing when used on surfaces. The present invention therefore also includes a method for the production of the cyanacrylate component described above, and the cyanacrylate component as such.

  本发明涉及一种聚合粘合剂组成物，至少包括一种氰基丙烯酸酯组分，并在表面使用时需要相对较短的固化时间。因此，本发明还包括上述氰基丙烯酸酯组分的制备方法以及氰基丙烯酸酯组分本身。
• CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL
  申请人：Salamone Beal Ann

  公开号：US20070041935A1

  公开（公告）日：2007-02-22

  Liquid hemostatic coating materials comprise a cyanoacrylate monomer and a solvent system comprising a volatile, non-reactive liquid that is non-stinging and non-irritating to a user. The material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.

  液态止血涂层材料包括氰基丙烯酸酯单体和溶剂体系，其中溶剂体系包括一种挥发性、非反应性液体，对用户无刺激性和无刺激性。该材料形成一种涂层或绷带形式的薄膜，当应用并粘附到表面或用户的皮肤上时，抑制应用表面与另一表面粘附。
• PROCESS FOR PREPARATION OF ALKYL AND ALCOXYALKYL-ALPHA-CYANOACRYLATES BY DEPOLYMERISATION OF POLY(ALKYL-ALPHA CYANOACRYLATES) OR POLY(ALCOXYALKYL-ALPHA-CYANOACRYLATES) AND ITS USAGE AS TECHNICAL AND/OR MEDICAL ADHESIVE
  申请人：Zlatev Denchev Zlatan

  公开号：US20090018360A1

  公开（公告）日：2009-01-15

  This invention is related to the preparation of alkyl or alkoxyalkyl-α-cyanoacrylates in monomeric form by depolymerisation of the corresponding poly(alkyl-α-cyanoacrylates) or poly(alkoxyalkyl-α-cyanoacrylates) (PCA). The PCA's are obtained preferably by base-catalyzed condensation of a cyanoacetate with formaldehyde (or a polymer of the latter). According to the invention, the poly(alkyl-α-cyanoacrylate) or poly(alkoxyalkyl-α-cyanoacrylate), the condensation product, is mixed with a depolymerisation system comprising phosphorus pentoxide P 2 O 5 , hydroquinone, ortho-phosphoric acid and para-toluenesulfonic acid. This process is realized in a batch reactor fitted with a condenser, heated at a temperature in the range of 100-300° C., under a vacuum of 0.5-50 Torr (7.10 −5 -7.10 −3 MPa) and gives rise to monomeric alkyl-α-cyanoacrylates or monomeric alkoxyalkyl-α-cyanoacrylates, being stable in both gaseous and liquid phase. After an additional purification by vacuum distillation, these cyanoacrylates can be used as fast setting technical or medical adhesives.

  本发明涉及通过降解相应的聚（烷基-α-氰基丙烯酸酯）或聚（烷氧基烷基-α-氰基丙烯酸酯）（PCA）制备单体形式的烷基或烷氧基烷基-α-氰基丙烯酸酯的方法。PCA首选是通过氰乙酸酯和甲醛（或后者的聚合物）的碱催化缩合反应得到的。根据本发明，将聚（烷基-α-氰基丙烯酸酯）或聚（烷氧基烷基-α-氰基丙烯酸酯）即缩合产物与包括五氧化二磷P2O5、对苯二酚、邻磷酸和对甲苯磺酸的降解系统混合。该过程在带有冷凝器的批式反应器中进行，在100-300℃的温度范围内加热，在0.5-50 Torr（7.10−5-7.10−3MPa）的真空下进行，并产生稳定的烷基-α-氰基丙烯酸酯单体或烷氧基烷基-α-氰基丙烯酸酯单体，无论是在气态还是液态下都稳定。经过真空蒸馏的额外纯化后，这些氰基丙烯酸酯可用作快速固化的技术或医用粘合剂。