2,2-dimethyl-4-(8-propoxyoctyl)-1,3-dioxolane | 1318779-86-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-dimethyl-4-(8-propoxyoctyl)-1,3-dioxolane
• 英文别名: 2,2-Dimethyl-4-(8-propoxyoctyl)-1,3-dioxolane
• CAS: 1318779-86-0
• 化学式: C₁₆H₃₂O₃
• 分子量: 272.428
• InChiKey: ANPMMEGWXXPPNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  、 丙酮 在 phosphotungstic acid 作用下， 反应 1.0h， 以89%的产率得到2,2-dimethyl-4-(8-propoxyoctyl)-1,3-dioxolane
  参考文献：
  名称：

  Useful methods for the synthesis of isopropylidenes and their chemoselective cleavage

  摘要：

  A catalytic amount of phosphotungstic acid (PTA) has been found to be a very effective catalyst for isopropylidenation of 1,2-diols and their deprotection at room temperature. The ease of handling, cost and activity of the catalyst, good to excellent yields and chemoselectivity for deprotection are some of the highlights of the reported method. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.050

文献信息

• Useful methods for the synthesis of isopropylidenes and their chemoselective cleavage
  作者：Khiangte Vanlaldinpuia、Ghanashyam Bez

  DOI：10.1016/j.tetlet.2011.05.050

  日期：2011.7

  A catalytic amount of phosphotungstic acid (PTA) has been found to be a very effective catalyst for isopropylidenation of 1,2-diols and their deprotection at room temperature. The ease of handling, cost and activity of the catalyst, good to excellent yields and chemoselectivity for deprotection are some of the highlights of the reported method. (C) 2011 Elsevier Ltd. All rights reserved.