9-(Methoxycarbonyl)-3,6-dioxanonanol | 143528-03-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-(Methoxycarbonyl)-3,6-dioxanonanol
• 英文别名: Methyl 4-[2-(2-hydroxyethoxy)ethoxy]butanoate；methyl 4-[2-(2-hydroxyethoxy)ethoxy]butanoate
• CAS: 143528-03-4
• 化学式: C₉H₁₈O₅
• 分子量: 206.239
• InChiKey: QSZLKKBZXHEPMI-UHFFFAOYSA-N

物化性质

• 沸点：
  294.6±25.0 °C(Predicted)
• 密度：
  1.080±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  9-(Methoxycarbonyl)-3,6-dioxanonanol 在 甲醇 、 sodium tetrahydroborate 、 乙醇 、 silver silicate 、 4 A molecular sieve 、 sodium methylate 、 nickel dichloride 作用下， 以 甲苯 为溶剂， 反应 6.0h， 生成 9-(Methoxycarbonyl)-3,6-dioxanonyl 2-acetamido-2-deoxy-α-D-mannopyranoside
  参考文献：
  名称：

  Synthesis of ω-(methoxycarbonyl)alkyl and 9-(methoxycarbonyl)-3,6-dioxanonyl glycopyranosides for the preparation of carbohydrate-protein conjugates

  摘要：

  Omega-(Methoxycarbonyl)alkyl glycopyranosides of D-mannose having C4, C-7, C-9, C-12, and C-15 carbon chains, L-fucose and 2-acetamido-2-deoxy-D-mannose having C-7 and C-9 carbon chains. D-xylose and 2-acetamido-2-deoxy-L-fucose having a C-9 carbon chian, and 9-(methoxycarbonyl)-3,6-dioxanoyl glycopyranosides of D-mannose. 2-acetamido-2-deoxy-D-mannose, and L-fucose were' synthesized as intermediates for coupling to human serum albumin in order to examine the effect of chain length and hydrophobicity of the spacer arm on the binding specificity of lectins. 8-(Methoxycarbonyl)octyl glycosides of beta-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-ManNAc-(1 --> 2)-alpha-D-Man, beta-D-GlcNAc-(1 --> 2)-alpha-D-Man, and their 6-O-positional isomers, beta-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-ManNAc-(1 --> 6)-alpha-D-Man, and beta-D-GlcNAc-(1 --> 6)-alpha-D-Man, were also synthesized.

  DOI：

  10.1016/s0008-6215(00)90517-2
• 作为产物：
  描述：

  三甘醇单苄醚 在 palladium on activated charcoal 水 、 氢气 、 三溴化磷 、 sodium hydride 、 sodium chloride 作用下， 以 甲醇 、 乙醚 、 二甲基亚砜 为溶剂， 反应 17.0h， 生成 9-(Methoxycarbonyl)-3,6-dioxanonanol
  参考文献：
  名称：

  Synthesis of ω-(methoxycarbonyl)alkyl and 9-(methoxycarbonyl)-3,6-dioxanonyl glycopyranosides for the preparation of carbohydrate-protein conjugates

  摘要：

  Omega-(Methoxycarbonyl)alkyl glycopyranosides of D-mannose having C4, C-7, C-9, C-12, and C-15 carbon chains, L-fucose and 2-acetamido-2-deoxy-D-mannose having C-7 and C-9 carbon chains. D-xylose and 2-acetamido-2-deoxy-L-fucose having a C-9 carbon chian, and 9-(methoxycarbonyl)-3,6-dioxanoyl glycopyranosides of D-mannose. 2-acetamido-2-deoxy-D-mannose, and L-fucose were' synthesized as intermediates for coupling to human serum albumin in order to examine the effect of chain length and hydrophobicity of the spacer arm on the binding specificity of lectins. 8-(Methoxycarbonyl)octyl glycosides of beta-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-ManNAc-(1 --> 2)-alpha-D-Man, beta-D-GlcNAc-(1 --> 2)-alpha-D-Man, and their 6-O-positional isomers, beta-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-ManNAc-(1 --> 6)-alpha-D-Man, and beta-D-GlcNAc-(1 --> 6)-alpha-D-Man, were also synthesized.

  DOI：

  10.1016/s0008-6215(00)90517-2

文献信息

• Ink, inkjet recording method, ink cartridge, and image recording device
  申请人：Hirade Tomohiro

  公开号：US10544321B2

  公开（公告）日：2020-01-28

  An ink includes a volatile solvent, an inorganic hollow particle, and a calcium ion, wherein the calcium ion has a proportion of from 0.5 to 250 ppm in the ink and the inorganic hollow particle has a 50 percent cumulative particle diameter of from 50 to 350 nm.

  一种油墨包括挥发性溶剂、无机空心颗粒和钙离子，其中钙离子在油墨中的比例为 0.5 至 250 ppm，无机空心颗粒 50% 的累积颗粒直径为 50 至 350 nm。
• JPH09118699A
  申请人：——

  公开号：JPH09118699A

  公开（公告）日：1997-05-06
• INK, INKJET RECORDING METHOD, INK CARTRIDGE, AND IMAGE RECORDING DEVICE
  申请人：HIRADE Tomohiro

  公开号：US20170349772A1

  公开（公告）日：2017-12-07

  An ink includes a volatile solvent, an inorganic hollow particle, and a calcium ion, wherein the calcium ion has a proportion of from 0.5 to 250 ppm in the ink and the inorganic hollow particle has a 50 percent cumulative particle diameter of from 50 to 350 nm.
• INK, INK ACCOMMODATING UNIT, RECORDING METHOD, RECORDING DEVICE, AND RECORDED MATTER
  申请人：Hirade Tomohiro

  公开号：US20190031897A1

  公开（公告）日：2019-01-31

  An ink contains a volatile solvent, a pigment including an inorganic hollow particle having a spherical form, and a resin particle.
• Synthesis of ω-(methoxycarbonyl)alkyl and 9-(methoxycarbonyl)-3,6-dioxanonyl glycopyranosides for the preparation of carbohydrate-protein conjugates
  作者：Tamio Sugawara、Kunihiko Irie、Hiroyuki Iwasawa、Takayoshi Yoshikawa、Satoshi Okuno、Hiroshi K. Watanabe、Takashi Kato、Mitsuru Shibukawa、Yukio Ito

  DOI：10.1016/s0008-6215(00)90517-2

  日期：1992.6

  Omega-(Methoxycarbonyl)alkyl glycopyranosides of D-mannose having C4, C-7, C-9, C-12, and C-15 carbon chains, L-fucose and 2-acetamido-2-deoxy-D-mannose having C-7 and C-9 carbon chains. D-xylose and 2-acetamido-2-deoxy-L-fucose having a C-9 carbon chian, and 9-(methoxycarbonyl)-3,6-dioxanoyl glycopyranosides of D-mannose. 2-acetamido-2-deoxy-D-mannose, and L-fucose were' synthesized as intermediates for coupling to human serum albumin in order to examine the effect of chain length and hydrophobicity of the spacer arm on the binding specificity of lectins. 8-(Methoxycarbonyl)octyl glycosides of beta-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-Man-(1 --> 2)-alpha-D-Man, alpha-D-ManNAc-(1 --> 2)-alpha-D-Man, beta-D-GlcNAc-(1 --> 2)-alpha-D-Man, and their 6-O-positional isomers, beta-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-Man-(1 --> 6)-alpha-D-Man, alpha-D-ManNAc-(1 --> 6)-alpha-D-Man, and beta-D-GlcNAc-(1 --> 6)-alpha-D-Man, were also synthesized.