1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-methyl-3,4-dihydroisoquinoline | 109979-90-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢异喹啉
• 英文名称: 1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-methyl-3,4-dihydroisoquinoline
• 英文别名: 6,7-Dimethoxy-3-methyl-1-(3,4-dimethoxy-phenyl)-3,4-dihydro-isochinolin；6,7-Dimethoxy-3-methyl-1-(3,4-dimethoxyphenyl)-3,4-dihydrochinolin；1-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-3-methyl-3,4-dihydro-isochinolin
• CAS: 109979-90-0
• 化学式: C₂₀H₂₃NO₄
• 分子量: 341.407
• InChiKey: IIJWEBBQQJBEJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  49.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-methyl-3,4-dihydroisoquinoline 在 palladium on activated charcoal 、 1,2,3,4-四氢萘 作用下， 生成 1-(3,4-Dimethoxy-phenyl)-3-methyl-6,7-dimethoxy-chinolin
  参考文献：
  名称：

  N-Acyl-β-phenethylamines, and a New Isoquinoline Synthesis

  摘要：

  DOI：

  10.1021/ja01123a053
• 作为产物：
  描述：

  3,4-二甲氧基-Alpha-甲基苯乙胺 在 甲苯 、 三氯氧磷 作用下， 生成 1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-methyl-3,4-dihydroisoquinoline
  参考文献：
  名称：

  Regulatory role of DREB transcription factors in plant drought, salt and cold tolerance

  摘要：

  rd29A gene of Arabidopsis encodes a LEA-like hydrophilic protein, its expression is induced by drought, high-salt and cold stress. In the promoter region of rd29A gene, there are 2 DRE cis-acting elements involved in responses to these environmental stresses. 5 cDNAs (DREB1A similar to C and DREB2A similar to B) encoding DREB transcription factors, which specifically bind to DRE element and control the expression of reporter gene under drought, high-salt and stress, have been isolated by One-Hybrid screening method and with DRE element of rd29A promoter. DREB transcription factors and DRE element function in signal transduction of drought, high-salt and cold stress. One DREB transcription factor can control the expression of several target functional genes involved in plant tolerance to drought, high-salt and cold stress. Thus, it may be an effective strategy to achieve ideal, multiple and fundamental effect for improving plant stress-resistance by DREB gene transfer.

  DOI：

  10.1007/bf02884972

文献信息

• Lora-Tamayo; Madronero, Festschrift A.Stoll<Basel 1957>S.220,223,224
  作者：Lora-Tamayo、Madronero

  DOI：——

  日期：——
• Kametani, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1952, vol. 72, p. 1537
  作者：Kametani

  DOI：——

  日期：——
• Madronero et al., Anales de la Real Sociedad Espanola de Fisica y Quimica, Serie B: Quimica, 1955, vol. 51, p. 465,467, 468
  作者：Madronero et al.

  DOI：——

  日期：——
• Lora-Tamayo; Madronero, 1959, vol. 53, p. 527,536,538
  作者：Lora-Tamayo、Madronero

  DOI：——

  日期：——
• N-Acyl-β-phenethylamines, and a New Isoquinoline Synthesis
  作者：John J. Ritter、Francis X. Murphy

  DOI：10.1021/ja01123a053

  日期：1952.2