meta-Hoechst | 132869-83-1

• 物质功能分类: 生物化工 - 生化试剂 - 荧光成像
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: meta-Hoechst
• 英文别名: 3-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol
• CAS: 132869-83-1
• 化学式: C₂₅H₂₄N₆O
• 分子量: 424.5
• InChiKey: WOFDIDGQAOQHGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  84.1
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• RNA TARGETING COMPOUNDS AND METHODS FOR MAKING AND USING SAME
  申请人：The Research Foundation Of State University Of New York

  公开号：EP2129388B1

  公开（公告）日：2012-09-12
• RNA targeting compounds and methods for making and using same
  申请人：Disney Matthew D.

  公开号：US20080227213A1

  公开（公告）日：2008-09-18

  Disclosed are RNA targeting compounds having the formula: wherein j is an integer from 1 to 100; each i is the same or different and is zero or an integer from 1 to 100; each Z 1 represents the same or different linking moiety; each R 1 is the same or different and represents an alkyl group or an aryl group; each Q 1 represents the same or different RNA binding ligand; Q 2 is an alkyl group; Q 3 is a halogen, an alkyl group, an aryl group, or an amine. Also disclosed are RNA targeting compounds that include a polymer backbone and two or more pendant RNA binding ligands that are bound to the polymer backbone. Methods for using the subject RNA targeting compounds to treat myotonic dystrophy and other diseases are also disclosed, as are compounds that can be used to prepare the subject RNA targeting compounds.
• US9150612B2
  申请人：——

  公开号：US9150612B2

  公开（公告）日：2015-10-06