9-[Bis(methylsulfanyl)methylidene]-10-methylacridine | 555152-95-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 9-[Bis(methylsulfanyl)methylidene]-10-methylacridine
• CAS: 555152-95-9
• 化学式: C₁₇H₁₇NS₂
• 分子量: 299.5
• InChiKey: PHAAOKTXPVIHOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  53.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase
  申请人：LUMIGEN, INC.

  公开号：EP2096110A1

  公开（公告）日：2009-09-02

  Novel compounds comprising a C-C double bound substituted at one carbon with two sulphur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a peroxide. The chemiluminescence thus produced can be used as a detactable signal in assays for peroxidase enzymes or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.

  本发明公开了由一个碳上被两个含硫原子基团取代的 C-C 双键组成的新型化合物。这些化合物适用于通过与过氧化物酶和过氧化物反应快速产生化学发光的方法和组合物。由此产生的化学发光可在过氧化物酶或产生过氧化物的酶的检测中以及在采用酶标记的特异性结合对的检测中用作可检测信号。
• IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE
  申请人：LUMIGEN, INC.

  公开号：EP1456176B1

  公开（公告）日：2009-03-18
• Assay Methods Using Chemiluminescent Detection of Peroxidase
  申请人：Akhavan-Tafti Hashem

  公开号：US20090246819A1

  公开（公告）日：2009-10-01

  Methods for generating chemiluminescence rapidly by reaction of at least one compound comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups with a peroxidase enzyme and a peroxide are disclosed. The chemiluminescence thus produced can be used as a detectable signal in assays for peroxidase enzymes or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs. Use of the methods provides rapid signal generation, achieving a plateau intensity in under one minute. The substrate can be provided in a composition which demonstrates unexpectedly long storage stability.
• US7247726B2
  申请人：——

  公开号：US7247726B2

  公开（公告）日：2007-07-24
• US7560556B2
  申请人：——

  公开号：US7560556B2

  公开（公告）日：2009-07-14