D-threo-D-galacto-octitol | 106356-26-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: D-threo-D-galacto-octitol
• 英文别名: D-threo-D-galacto-octicol；(2S,3R,4R,5R,6S,7R)-octane-1,2,3,4,5,6,7,8-octol
• CAS: 106356-26-7
• 化学式: C₈H₁₈O₈
• 分子量: 242.226
• InChiKey: DRDSDQVQSRICML-WNBCZPBOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  162
• 氢给体数：
  8
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  6,7-anhydro-1,2:3,4-di-O-isopropylidene-α-L-erythro-D-galacto-octopyranose 在 sodium hydroxide 、 sodium tetrahydroborate 、 水 、 三氟乙酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 20.25h， 生成 D-threo-D-galacto-octitol
  参考文献：
  名称：

  Brimacombe, John S.; Kabir, Abul K. M. S.; Bennett, Frank, Journal of the Chemical Society. Perkin transactions I, 1986, p. 1677 - 1680

  摘要：

  DOI：

文献信息

• Cosmetic composition
  申请人：UNILEVER PLC

  公开号：EP0407089A2

  公开（公告）日：1991-01-09

  A water-in-silicone oil transparent emulsion is made from a volatile polydimethylsiloxane (1 to 50% by weight), a silicone surfactant (0.1 to 20% by weight), at least one polyhydric alcohol (1 to 50% by weight) and water. The silicone surfactant comprises a polymer of dimethyl polysiloxane with polyoxyethylene and/or polyoxypropylene side chains having a molecular weight of from 10,000 to 50,000 and having the structure: a having a value of from 9 to 115, b having a value of from 0 to 50, x having a value of from 133 to 673, y having a value of from 25 to 0.25.

  一种水包硅油透明乳液是由挥发性聚二甲基硅氧烷（1-50%（重量））、硅氧烷表面活性剂（0.1-20%（重量））、至少一种多元醇（1-50%（重量））和水制成。 硅氧烷表面活性剂包括二甲基聚硅氧烷与聚氧乙烯和/或聚氧丙烯侧链的聚合物，其分子量为 10,000 至 50,000 之间，结构如下： a 值为 9 至 115、 b 的值为 0 至 50、 x 的值为 133 至 673、 y 的值为 25 至 0.25。
• METHOD FOR INDUCING CELL DEATH IN PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS OTHER THAN CARDIAC MYOCYTES
  申请人：Daiichi Sankyo Company, Limited

  公开号：EP2415862A1

  公开（公告）日：2012-02-08

  The present invention has as its object developing a method that does not involve genomic modification and which yet is capable of inducing cell death in pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, as well as in differentiated cells other than cardiomyocytes derived from pluripotent stem cells, but not in cardiomyocytes. It has been revealed that by establishing a method capable of inducing cell death in cells other than cardiomyocytes in a very efficient manner by adding a substance having no recognized inherent toxicity or cell death inducing action to the culture conditions for pluripotent stem cells and non-cardiomyocytes, the stated problem can be solved without relying upon genomic modification.

  本发明的目的是开发一种不涉及基因组改造的方法，该方法能够诱导胚胎干细胞和诱导多能干细胞等多能干细胞以及由多能干细胞衍生的心肌细胞以外的分化细胞（但不是心肌细胞）中的细胞死亡。研究发现，通过在多能干细胞和非心肌细胞的培养条件中加入一种不具有公认的固有毒性或细胞死亡诱导作用的物质，建立一种能够以非常有效的方式诱导心肌细胞以外的细胞死亡的方法，可以解决上述问题，而无需依赖基因组改造。
• ORGANIC/INORGANIC HYBRID AND PROCESS FOR PRODUCING SAME
  申请人：National Institute for Materials Science

  公开号：EP2634137A1

  公开（公告）日：2013-09-04

  The invention has for its objects to provide an organic/inorganic hybrid that has high flame retardancy, flexibility, moldability and affinities for organic compounds, and is capable of including therein an organic compound having a large number of carbon atoms. The organic/inorganic hybrid comprises a layered hydroxide mineral 40 with sheet-like inorganic compound unit layers 11a, 11b, 11c and 11d and an organic compound 13 included between the inorganic compound unit layers 11a, 11b, 11c and 11d. The above objects are achievable by using as the hydroxide mineral 40 at least one hydroxide mineral selected from the group consisting of Mg(OH)2, Ca(OH)2, Al(OH)3, AlO(OH), Fe(OH)3 and FeO(OH), and as the organic compound 13 a saccharide having 4 to 40 carbon atoms.

  本发明的目的是提供一种有机/无机混合物，它具有高阻燃性、柔韧性、可模塑性和对有机化合物的亲和性，并且能够在其中包含具有大量碳原子的有机化合物。 有机/无机杂化物包括具有片状无机化合物单元层 11a、11b、11c 和 11d 的层状氢氧化物矿物 40，以及包含在无机化合物单元层 11a、11b、11c 和 11d 之间的有机化合物 13。通过使用至少一种选自 Mg(OH)2、Ca(OH)2、Al(OH)3、AlO(OH)、Fe(OH)3 和 FeO(OH)组成的组的氢氧化物矿物 40 作为氢氧化物矿物，以及使用具有 4 至 40 个碳原子的糖作为有机化合物 13，可实现上述目的。
• COMPOSITION FOR FORMING CONDUCTIVE FILM, AND CONDUCTIVE FILM MANUFACTURING METHOD USING SAME
  申请人：FUJIFILM Corporation

  公开号：EP2980169A1

  公开（公告）日：2016-02-03

  Provided is a composition for forming a conductive film, said composition containing: copper oxide particles (A) having an average particle size of 10-500 nm; copper particles (B) having an average particle size of 100-1000 nm; a polyol compound (C) which has two or more hydroxyl groups in the molecule; and at least one solvent (D) selected from the group consisting of water, and a water-soluble solvent. The ratio of the total mass (WA) of the copper oxide particles (A) to the total mass (WB) of the copper particles (B) is WA:WB=1:3-3:1, and the ratio of the sum total mass (WAB) of the copper oxide particles (A) and the copper particles (B) to the total mass (WC) of the polyol compound (C) is WAB:WC=20:1-2:1. The composition is capable of forming a conductive film which has high conductivity, and exhibits excellent adhesion to a substrate. Also provided is a conductive film manufacturing method using the composition.

  本发明提供了一种用于形成导电膜的组合物，所述组合物包含：平均粒径为 10-500 nm 的氧化铜颗粒（A）；平均粒径为 100-1000 nm 的铜颗粒（B）；分子中含有两个或两个以上羟基的多元醇化合物（C）；以及至少一种选自水和水溶性溶剂的溶剂（D）。氧化铜颗粒（A）的总质量（WA）与铜颗粒（B）的总质量（WB）之比为 WA:WB=1:3-3:1，氧化铜颗粒（A）和铜颗粒（B）的总质量之和（WAB）与多元醇化合物（C）的总质量（WC）之比为 WAB:WC=20:1-2:1。该组合物能够形成具有高导电性的导电膜，并且与基材具有良好的粘附性。此外，还提供了一种使用该组合物的导电膜制造方法。
• EMULSION COMPOSITION FOR PREVENTING OR AMELIORATING SNORING
  申请人：Nitto Pharmaceutical Industries, Ltd.

  公开号：EP3332794A1

  公开（公告）日：2018-06-13

  The present invention provides an emulsion composition containing (A) a vegetable oil, (B) a sugar alcohol having a carbon number of not less than 4 and (C) an emulsifier, or further, (D) a plant essential oil, which composition is superior in emulsion stability, suppresses separation and the like of the contained components during preservation, can be applied conveniently to a pharyngeal region without requiring a homogenizing operation at the time of application, and can be ingested or used continuously.

  本发明提供了一种乳液组合物，其中含有 (A) 植物油、(B) 碳原子数不小于 4 的糖醇和 (C) 乳化剂，或 (D) 植物精油，该组合物具有优异的乳液稳定性，在保存过程中可抑制所含成分的分离等现象，可方便地涂抹于咽部区域，而无需在涂抹时进行均质操作，并且可以连续摄入或使用。