[2-(5-ethoxy-indol-3-yl)-ethyl]-dimethyl-amine | 855245-09-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: [2-(5-ethoxy-indol-3-yl)-ethyl]-dimethyl-amine
• 英文别名: [2-(5-Aethoxy-indol-3-yl)-aethyl]-dimethyl-amin；5-Ethoxy-DMT；2-(5-ethoxy-1H-indol-3-yl)-N,N-dimethylethanamine
• CAS: 855245-09-9
• 化学式: C₁₄H₂₀N₂O
• 分子量: 232.326
• InChiKey: OSUDCFCSUHGWJF-UHFFFAOYSA-N

物化性质

• 沸点：
  383.3±32.0 °C(Predicted)
• 密度：
  1.078±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  28.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  [2-(5-ethoxy-indol-3-yl)-ethyl]-dimethyl-amine 在 三氯化铝 、 苯 作用下， 生成 蟾毒色胺
  参考文献：
  名称：

  Hoshino; Shimodaira, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 19,26

  摘要：

  DOI：
• 作为产物：
  描述：

  (5-乙氧基-吲哚-3-基)-乙酸 在 盐酸 、 乙醚 、 乙醇 、 sodium 、 三溴化磷 作用下， 生成 [2-(5-ethoxy-indol-3-yl)-ethyl]-dimethyl-amine
  参考文献：
  名称：

  Hoshino; Shimodaira, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 19,26

  摘要：

  DOI：

文献信息

• [EN] NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER<br/>[FR] NOUVELLES COMPOSITIONS ET PROCÉDÉS POUR TRAITER LE CANCER
  申请人：UNIV TEXAS

  公开号：WO2013063492A1

  公开（公告）日：2013-05-02

  Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.

  本文提供了用于治疗疾病的方法和组合物，包括治疗过度增殖性疾病、偏头痛和抑郁症等。
• NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER
  申请人：Board of Regents, The University of Texas System

  公开号：US20130129812A1

  公开（公告）日：2013-05-23

  Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.

  本文提供了用于治疗疾病的方法和组合物，包括治疗增生性疾病、偏头痛和抑郁症的方法和组合物。
• Novel Compositions and Methods for Treating Cancer
  申请人：Board of Regents, The University of Texas System

  公开号：US20150306077A1

  公开（公告）日：2015-10-29

  Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.

  本文提供了治疗疾病的方法和组合物，包括治疗高增殖性疾病、偏头痛和抑郁症等疾病的方法和组合物。
• Kobayashi, Justus Liebigs Annalen der Chemie, 1938, vol. 536, p. 143,156
  作者：Kobayashi

  DOI：——

  日期：——
• Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness
  申请人：Dresdner, JR. Karl P.

  公开号：US20200345585A1

  公开（公告）日：2020-11-05

  The invention relates to processes for making pharmaceutical aqueous therapeutic particles (AQTP) having stable exterior water clustering with nanosized thickness less than 300 nanometers, wherein the AQTP has an improved bioavailability when administered to a mammal compared to conventional pharmaceutical drug particles administered to the mammal. The invention relates to an improved process apparatus which is computer controlled, capable of continuous operation with high efficiency so as to make a more consistently acceptable AQTP compared to an previous prototype process apparatus of the Inventors. The invention provides compositions comprising of AQTP which comprise a substance selected from the group consisting of a cannabinoid such as CBD, a cell membrane pore-forming peptide such as PNC-27, a psychoactive drug, a pharmaceutical, a nutraceuticals, a mineral, an anion, a cation, a protein, a peptide, an amino acid, a polymer, a vitamins, an antioxidants, a fertilizer, a chemical, a medical use product, a medical kit use product, a personal consumer use product, a manufacturing use product, a energy use product such as a battery, and any combination thereof.