2-羟基-二十二烷酸甲酯 | 13980-17-1

• 物质功能分类: 分析化学 - 食品安全 - 脂肪酸、脂肪酸甲酯
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-羟基-二十二烷酸甲酯
• 英文名称: methyl 2-hydroxydocosanoate
• CAS: 13980-17-1
• 化学式: C₂₃H₄₆O₃
• mdl: MFCD00083372
• 分子量: 370.616
• InChiKey: KUHHQOLYDNMSJW-UHFFFAOYSA-N

物化性质

• 沸点：
  401.6±13.0 °C(Predicted)
• 密度：
  0.904±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  26
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.956
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• WGK Germany：
  3
• 海关编码：
  2918199090

反应信息

• 作为产物：
  描述：

  二十二烷酰胺,N-[1-[(b-D-吡喃葡萄糖氧基)甲基]-2,3-二羟基-5-十七碳烯基]-2-羟基-(9CI) 生成 2-羟基-二十二烷酸甲酯
  参考文献：
  名称：

  HIRSCH, S.;KASHMAN, Y., TETRAHEDRON, 45,(1989) N2, C. 3897-3906

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID ESTER
  申请人：Kaneka Corporation

  公开号：EP2067769A1

  公开（公告）日：2009-06-10

  It is an objective of the present invention to produce an anti-form of an optically active β-hydroxy-α-aminocarboxylic acid ester efficiently, simply and industrially advantageously. The objective can be accomplished by directly and selectively producing the anti-form of the optically active β-hydroxy-α-aminocarboxylic acid ester by asymmetric reduction of a β-keto-α-aminocarboxylic acid ester using an optically active amine complex as a catalyst. Further, the β-keto-α-aminocarboxylic acid ester as a raw material can be produced at a high yield by reacting a glycine derivative with a carboxylic acid derivative.

  本发明的目的是高效、简单、具有工业优势地生产光学活性β-羟基-α-氨基羧酸酯的反式形式。该目的可以通过使用光学活性胺络合物作为催化剂，通过不对称还原β-酮基-α-氨基羧酸酯直接和选择性地生产光学活性β-羟基-α-氨基羧酸酯的反式形式来实现。此外，将甘氨酸衍生物与羧酸衍生物反应可以高产率地生产β-酮基-α-氨基羧酸酯作为原料。
• Process for producing optically active beta-hydroxy-alpha-aminocarboxylic acid ester
  申请人：Honda Tatsuya

  公开号：US20100022795A1

  公开（公告）日：2010-01-28

  It is an objective of the present invention to produce an anti-form of an optically active β-hydroxy-α-aminocarboxylic acid ester efficiently, simply and industrially advantageously. The objective can be accomplished by directly and selectively producing the anti-form of the optically active β-hydroxy-α-aminocarboxylic acid ester by asymmetric reduction of a β-keto-α-aminocarboxylic acid ester using an optically active amine complex as a catalyst. Further, the β-keto-α-aminocarboxylic acid ester as a raw material can be produced at a high yield by reacting a glycine derivative with a carboxylic acid derivative.

  本发明的目的是高效、简单、工业上具有优势地生产一种光学活性的β-羟基-α-氨基羧酸酯的反式形式。该目标可以通过使用光学活性胺配合物作为催化剂，直接选择性地通过不对称还原β-酮基-α-氨基羧酸酯来生产光学活性β-羟基-α-氨基羧酸酯的反式形式来实现。此外，可以通过将甘氨酸衍生物与羧酸衍生物反应来高产地生产β-酮基-α-氨基羧酸酯原料。
• New glycosphingolipids from marine organisms
  作者：S. Hirsch、Y. Kashman

  DOI：10.1016/s0040-4020(01)89249-8

  日期：1989.1
• US8207370B2
  申请人：——

  公开号：US8207370B2

  公开（公告）日：2012-06-26
• [EN] THERAPEUTIC COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES ET LEURS UTILISATIONS
  申请人：MANUKA HEALTH NEW ZEALAND LTD

  公开号：WO2017164750A1

  公开（公告）日：2017-09-28

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-epithelial cancer compositions, containing glyceride compounds, and compositions comprising one or more of these compounds. Methods of preparing and using such compositions, in particular in the treatment or prevention of epithelial cancers, such as skin cancers, gastrointestinal cancers, and skin disorders, are also provided.