2-羟基-二十六烷酸 | 14176-13-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-羟基-二十六烷酸
• 英文名称: 2-hydroxyhexacosanoic acid
• 英文别名: 2‐hydroxyhexacosanoic acid；alpha-hydroxyhexacosanoic acid；hydroxyhexacosanoic acid；α-hydroxyhexacosanoic acid
• CAS: 14176-13-7
• 化学式: C₂₆H₅₂O₃
• 分子量: 412.697
• InChiKey: IFYDZTDBJZWEPK-UHFFFAOYSA-N

物化性质

• 熔点：
  103-105 °C
• 沸点：
  532.7±23.0 °C(Predicted)
• 密度：
  0.916±0.06 g/cm3(Predicted)
• LogP：
  11.520 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  11.8
• 重原子数：
  29
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  zinc(II) nitrate 、 2-羟基-二十六烷酸 以 乙醇 为溶剂， 以>95的产率得到zinc(II) hydroxyhexacosanoate
  参考文献：
  名称：

  锌（II）促进了2-羟酸酯的水解。羧肽酶A模型

  摘要：

  天然存在的2-羟基酸的Zn（II）配合物已通过两种单独的方法制备：（1）2-羟基酸与Zn（II）的反应；（2）Zn（II）促进的2-羟基酸的酯的水解。例如，在温暖的95％乙醇中0-乙酰基2-羟基十八碳烯酸与Zn（II）的反应导致形成Zn（2-羟基十八碳酸酯）2。该一般反应应提供洞察力，以羧肽酶催化的酯水解中离去基团的金属离子活化的重要性。

  DOI：

  10.1016/0022-1902(80)80069-8

文献信息

• Cosmetic compositions
  申请人：The Procter & Gamble Company

  公开号：US20020018760A1

  公开（公告）日：2002-02-14

  The present invention relates to pigmented emulsion cosmetic compositions containing emulsifying silicone elastomers that provide a natural appearance to the skin upon application. In particular, these cosmetic compositions are formulated such that agglomeration of the pigment upon application to the skin is minimized.

  本发明涉及含有乳化硅弹性体的颜料乳液化妆品组合物，该组合物在涂抹后能为皮肤提供自然外观。特别是，这些化妆品组合物的配方使得在涂抹到皮肤上时颜料的团聚最小化。
• Personal care compositions comprising solid particles enterapped in a gel network
  申请人：——

  公开号：US20030190336A1

  公开（公告）日：2003-10-09

  The present invention relates to a personal care composition comprising a three dimensional gel polymeric network comprising: a. a polymer; b. one or more solid particles that are entrapped within said polymer during polymerization of said polymer; and c. a solvent in which said polymer is dispersed. Another embodiment further includes at least one second colorant that is substantially similar to an at least one first colorant which is a solid particle and wherein said second colorant is dispersed within said composition but is not entrapped in said polymer and is separate and distinct from said network. In contrast, a third embodiment allows for the at least one second colorant to be substantially different from the at least one first colorant.

  本发明涉及一种个人护理组合物，包括三维凝胶聚合网络，其中包括： a. 聚合物； b. 在聚合物聚合过程中被包埋在聚合物中的一个或多个固体颗粒；以及 c. 一种将聚合物分散其中的溶剂。 另一实施方式进一步包括至少一种第二颜料，其与至少一种第一颜料（固体颗粒）在本质上相似，其中第二颜料分散在该组合物中但未被包埋在聚合物中，并且与该网络分开且独立。相比之下，第三实施方式允许至少一种第二颜料与至少一种第一颜料大不相同。
• Anhydrous cosmetic compositions
  申请人：——

  公开号：US20020018791A1

  公开（公告）日：2002-02-14

  An anhydrous skin treatment composition is provided which includes a crosslinked emulsifying siloxane elastomer, at least 20% humectant and a volatile siloxane. Inclusion of the elastomer provides a non-traditional smooth/silky feel to the skin upon application with a non-draggy rub in.

  提供了一种无水皮肤护理组合物，包括交联乳化硅氧烷弹性体、至少20%保湿剂和挥发性硅氧烷。包含弹性体可在涂抹时为皮肤提供非传统的光滑/丝滑感觉，摩擦时不会有拖拉感。
• COMPOSITIONS COMPRISING POLYMERS PREPARED FROM 2-HYDROXYALKYL ACIDS
  申请人：Moeller Michael

  公开号：US20130131190A1

  公开（公告）日：2013-05-23

  Described herein are compositions comprising polymers prepared by melt polycondensation of 2-hydroxyalkyl acids. Methods of making and using the compositions are also disclosed.

  本文描述了由2-羟基烷基酸熔融缩聚制备的聚合物组成物。还公开了制备和使用该组成物的方法。
• Refrigerator oil composition
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0802254A1

  公开（公告）日：1997-10-22

  Disclosed is a refrigerator oil composition comprising at least one base oil selected from mineral oils and synthetic oils, and at least one hydroxy-fatty acid derivative selected from (A) hydroxy-fatty acids or their condensates, (B) metal salts or amine salts of hydroxy-fatty acids or their condensates, and (C) esters of hydroxy-fatty acids. The composition has an excellent lubricating property, while specifically improving the lubricity between aluminium materials and steel materials. This is effective for preventing such materials from being seized and worn, and is suitable as a lubricating oil in refrigerators using hydrogen-containing Flon refrigerants, such as R134a, that do not cause environmental pollution.

  本发明公开了一种冷冻机油组合物，该组合物包含至少一种选自矿物油和合成油的基础油，以及至少一种选自 (A) 羟基脂肪酸或其缩合物、(B) 羟基脂肪酸或其缩合物的金属盐或胺盐，以及 (C) 羟基脂肪酸酯的羟基脂肪酸衍生物。该组合物具有极佳的润滑性能，尤其能改善铝材料和钢材料之间的润滑性。这可有效防止此类材料卡死和磨损，适用于使用不会造成环境污染的含氢氟隆制冷剂（如 R134a）的冰箱的润滑油。