Primeverose-heptaacetat | 18431-63-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Primeverose-heptaacetat
• 英文别名: Hepta-O-acetyl-β-primverose；Xyl2Ac3Ac4Ac(b1-6)b-Glc1Ac2Ac3Ac4Ac；[(3R,4S,5R,6R)-4,5-diacetyloxy-6-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetraacetyloxyoxan-2-yl]methoxy]oxan-3-yl] acetate
• CAS: 18431-63-5
• 化学式: C₂₅H₃₄O₁₇
• 分子量: 606.535
• InChiKey: WRTUKZXRBLWQSG-HIYHGCMWSA-N

物化性质

• 熔点：
  216 °C
• 沸点：
  609.4±55.0 °C(Predicted)
• 密度：
  1.36±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  42
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  212
• 氢给体数：
  0
• 氢受体数：
  17

反应信息

• 作为产物：
  描述：

  tetra-O-acetyl-β-D-xylopyranose 在 N-碘代丁二酰亚胺 、 三氟甲磺酸 、 四氯化锡 作用下， 生成 Primeverose-heptaacetat
  参考文献：
  名称：

  Biological activities of synthetic triterpenoid and steroid β-d-xylopyranosyl-(1 → 6)-β-d-glucopyranosides

  摘要：

  Comparisons of the activities of diosgenyl, methyl glycyrrhetinate or digitoxigenyl 3-O-beta-D-xylopyranosyl-(1 --> 6)-beta-D-glucopyranoside with those of our previous glycosides supported our assumptions that both haemolytic and antifungal activities of steroid saponins are generally parallel to each other, while almost all haemolytic triterpenoid saponins show no antifungal activity, and that both antiviral and anti-ATPase activities of cardiac glycosides having a (1-->6) sugar linkage are much lower than those of the others. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0031-9422(96)00547-x

文献信息

• Helferich; Steinpreis, Chemische Berichte, 1958, vol. 91, p. 1794,1797
  作者：Helferich、Steinpreis

  DOI：——

  日期：——
• The Preparation of β-Primeverose Heptaacetate and β-Vicianose Heptaacetate
  作者：Chester M. McCloskey、George H. Coleman

  DOI：10.1021/ja01249a505

  日期：1943.9
• Biological activities of synthetic triterpenoid and steroid β-d-xylopyranosyl-(1 → 6)-β-d-glucopyranosides
  作者：Masayuki Takechi、Chikari Uno、Yasuo Tanaka

  DOI：10.1016/s0031-9422(96)00547-x

  日期：1997.1

  Comparisons of the activities of diosgenyl, methyl glycyrrhetinate or digitoxigenyl 3-O-beta-D-xylopyranosyl-(1 --> 6)-beta-D-glucopyranoside with those of our previous glycosides supported our assumptions that both haemolytic and antifungal activities of steroid saponins are generally parallel to each other, while almost all haemolytic triterpenoid saponins show no antifungal activity, and that both antiviral and anti-ATPase activities of cardiac glycosides having a (1-->6) sugar linkage are much lower than those of the others. Copyright (C) 1996 Elsevier Science Ltd