2-Chloro-1-methylquinolin-1-ium | 45998-43-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-Chloro-1-methylquinolin-1-ium
• CAS: 45998-43-4
• 化学式: C10H9ClN+
• 分子量: 178.64
• InChiKey: BTGAPGLGVRNSDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Preparation of Mono-/Difluorinated Hydrocarbon Compounds
  申请人：Saint-Jalmes Laurent

  公开号：US20090234151A1

  公开（公告）日：2009-09-17

  Mono- or difluorinated hydrocarbon compounds are prepared from an alcohol or a carbonylated compound by reacting one of these with a fluorinating reagent, optionally in the presence of a base, the fluorinating agent comprising a pyridinium reactant having the following formula (F), wherein R 0 is an alkyl or cycloalkyl radical:

  从醇或羰基化合物中制备单氟或二氟烃化合物，通过将其中一种与氟化试剂反应制备，可选地在碱的存在下，氟化剂包括具有以下公式（F）的吡啶反应物，其中R0是烷基或环烷基基团。
• [EN] PYRIDINIUM, QUINOLINIUM, ACRIDINIUM, PYRYLIUM, CHROMENYLIUM OR XANTHYLIZUM REACTIVE DESORPTION AND/OR LASER ABLATION IONIZATION MATRICES AND USE THEREOF<br/>[FR] MATRICES D'IONISATION RÉACTIVES AVEC DÉSORPTION ET/OU ABLATION LASER ET LEUR UTILISATION
  申请人：ANDREN PER

  公开号：WO2019172830A1

  公开（公告）日：2019-09-12

  The present disclosure concerns use of compounds of formula I, or salts thereof, as reactive matrices for desorption and laser ablation ionization spectrometry. The disclosure further concerns compounds of formula II, or salts thereof, and use of compounds of formula II or III, or salts thereof.

  本公开涉及化合物I的使用，或其盐，作为脱附和激光解吸电离光谱的反应基质。本公开进一步涉及化合物II，或其盐，以及化合物II或III的使用，或其盐。
• METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES
  申请人：Toray Industries, Inc.

  公开号：EP3862431A1

  公开（公告）日：2021-08-11

  The present invention relates to a method for producing a hairpin single-stranded RNA molecule capable of inhibiting expression of a target gene, comprising the step of reacting a first single-stranded oligo-RNA molecule represented by the following formula (I) with a second single-stranded oligo-RNA molecule represented by the following formula (II) in a mixed solvent comprising a buffer solution and a hydrophilic organic solvent in the presence of a dehydration condensation agent: 5'-Xc-Lx1 ... (I) and Lx2-X-Y-Ly-Yc-3' ... (II), wherein the dehydration condensation agent is selected from the group consisting of a triazine-based dehydration condensation agent, a uronium-based dehydration condensation agent comprising an N-hydroxy nitrogen-containing aromatic ring structure, a carbodiimide-based dehydration condensation agent, a 2-halopyridinium-based dehydration condensation agent, and a formamidinium-based dehydration condensation agent.

  本发明涉及一种生产能够抑制靶基因表达的发夹型单链 RNA 分子的方法，包括以下步骤： 在由缓冲溶液和亲水性有机溶剂组成的混合溶剂中，在脱水缩合剂存在的情况下，由下式 (I) 表示的第一单链寡核苷酸分子与由下式 (II) 表示的第二单链寡核苷酸分子反应： 5'-Xc-Lx1 ...... (I) 和 Lx2-X-Y-Ly-Yc-3' ...... (II) ，其中脱水缩合剂选自由三嗪类脱水缩合剂、脲类脱水缩合剂、脲类脱水缩合剂和脲类脱水缩合剂组成的组。...(I)和 Lx2-X-Y-Ly-Yc-3' ...(II)，其中脱水缩合剂选自由三嗪基脱水缩合剂、包含 N-羟基含氮芳香环结构的脲基脱水缩合剂、碳二亚胺基脱水缩合剂、2-卤代吡啶鎓基脱水缩合剂和甲脒基脱水缩合剂组成的组。
• 1-benzopyrane-derivatives and colouring agents containing the salts thereof
  申请人：——

  公开号：US20030196281A1

  公开（公告）日：2003-10-23

  The present invention concerns an agent for coloring fibers that is obtained by mixing two components—if necessary with the addition of an alkalinizing agent or an acid—said agent being characterized in that one component (component A2) contains at least one electrophilic compound and the other component (component A1) contains at least one 1-benzopyran of formula (Ia)/(Ib) or a 1-benzopyrylium derivative of formula (I), 1 and a method for temporarily coloring keratin fibers whereby the hair is first colored with the aforesaid coloring agent and then, at any future time, is again decolorized with a reducing agent.

  本发明涉及一种纤维着色剂，该着色剂由两种组分混合而成，必要时加入碱化剂或酸，其特征在于其中一种组分（组分 A2）含有至少一种亲电化合物，另一种组分（组分 A1）含有至少一种式 (Ia)/(Ib) 的 1-苯并吡喃或式 (I) 的 1-苯并吡喃衍生物、 1 以及一种对角蛋白纤维进行临时着色的方法，首先用上述着色剂对头发进行着色，然后，在以后的任何时间，再用还原剂对头发进行脱色。
• SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS
  申请人：F. Hoffmann-La Roche AG

  公开号：EP1891001A1

  公开（公告）日：2008-02-27